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We introduce the Stackelberg kidney exchange problem. In this problem, an agent (e.g. a hospital or a national organization) has control over a number of incompatible patient-donor pairs whose patients are in need of a transplant. The agent…

Computer Science and Game Theory · Computer Science 2020-07-08 Bart Smeulders , Danny Blom , Frits C. R. Spieksma

Chronic kidney disease (CKD) is a significant public health challenge, often progressing to end-stage renal disease (ESRD) if not detected and managed early. Early intervention, warranted by silent disease progression, can significantly…

Machine Learning · Computer Science 2024-11-19 Zachary Dana , Ahmed Ammar Naseer , Botros Toro , Sumanth Swaminathan

Network reliability is a well-studied problem that requires to measure the probability that a target node is reachable from a source node in a probabilistic (or uncertain) graph, i.e., a graph where every edge is assigned a probability of…

Social and Information Networks · Computer Science 2018-05-01 Arijit Khan , Francesco Bonchi , Francesco Gullo , Andreas Nufer

We consider the problem of learning the weighted edges of a balanced mixture of two undirected graphs from epidemic cascades. While mixture models are popular modeling tools, algorithmic development with rigorous guarantees has lagged.…

Social and Information Networks · Computer Science 2020-01-30 Jessica Hoffmann , Soumya Basu , Surbhi Goel , Constantine Caramanis

We study an elementary path problem which appears in the pricing step of a column generation scheme solving the kidney exchange problem. The latter aims at finding exchanges of donations in a pool of patients and donors of kidney…

Data Structures and Algorithms · Computer Science 2022-01-24 Lucie Pansart , Hadrien Cambazard , Nicolas Catusse

A large number of applications such as querying sensor networks, and analyzing protein-protein interaction (PPI) networks, rely on mining uncertain graph and hypergraph databases. In this work we study the following problem: given an…

Data Structures and Algorithms · Computer Science 2018-01-11 Charalampos E. Tsourakakis , Shreyas Sekar , Johnson Lam , Liu Yang

We develop a novel mathematical programming approximation framework to tackle the stochastic knapsack problem. In this problem, the decision maker considers items for which either weights or values, or both, are random. The aim is to select…

Optimization and Control · Mathematics 2025-12-18 Roberto Rossi , Steven D. Prestwich , S. Armagan Tarim

Chance-constrained problems involve stochastic components in the constraints which can be violated with a small probability. We investigate the impact of different types of chance constraints on the performance of iterative search…

Neural and Evolutionary Computing · Computer Science 2024-05-30 Saba Sadeghi Ahouei , Jacob de Nobel , Aneta Neumann , Thomas Bäck , Frank Neumann

In this paper, the dynamic constrained optimization problem of weights adaptation for heterogeneous epidemic spreading networks is investigated. Due to the powerful ability of searching global optimum, evolutionary algorithms are employed…

Neural and Evolutionary Computing · Computer Science 2024-12-20 Yun Feng , Bing-Chuan Wang

Cardiac rehabilitation constitutes a structured clinical process involving multiple interdependent phases, individualized medical decisions, and the coordinated participation of diverse healthcare professionals. This sequential and adaptive…

Machine Learning · Computer Science 2025-12-25 Alexandre Cabodevila , Pedro Gamallo-Fernandez , Juan C. Vidal , Manuel Lama

We revisit the problem of designing optimal, individually rational matching mechanisms (in a general sense, allowing for cycles in directed graphs), where each player --- who is associated with a subset of vertices --- matches as many of…

Data Structures and Algorithms · Computer Science 2016-09-15 Avrim Blum , Ioannis Caragiannis , Nika Haghtalab , Ariel D. Procaccia , Eviatar B. Procaccia , Rohit Vaish

To overcome incompatibility issues, kidney patients may swap their donors. In international kidney exchange programmes (IKEPs), countries merge their national patient-donor pools. We consider a recently introduced credit system. In each…

Computer Science and Game Theory · Computer Science 2023-02-24 Márton Benedek , Péter Biró , Daniël Paulusma , Xin Ye

We consider the {\em stochastic matching} problem. An edge-weighted general (i.e., not necessarily bipartite) graph $G(V, E)$ is given in the input, where each edge in $E$ is {\em realized} independently with probability $p$; the…

Data Structures and Algorithms · Computer Science 2018-05-24 Soheil Behnezhad , Nima Reyhani

In generalized regression models the effect of continuous covariates is commonly assumed to be linear. This assumption, however, may be too restrictive in applications and may lead to biased effect estimates and decreased predictive…

Methodology · Statistics 2023-11-01 Nikolai Spuck , Matthias Schmid , Moritz Berger

We study pattern matching problems on two major representations of uncertain sequences used in molecular biology: weighted sequences (also known as position weight matrices, PWM) and profiles (i.e., scoring matrices). In the simple version,…

Data Structures and Algorithms · Computer Science 2016-07-12 Tomasz Kociumaka , Solon P. Pissis , Jakub Radoszewski

Kidney donations from living donors form an attractive alternative to long waiting times on a list for a post-mortem donation. However, even if a living donor for a given patient is found, the donor's kidney might not meet the patient's…

Cryptography and Security · Computer Science 2020-11-11 Malte Breuer , Ulrike Meyer , Susanne Wetzel , Anja Mühlfeld

Matching on covariates is a well-established framework for estimating causal effects in observational studies. The principal challenge stems from the often high-dimensional structure of the problem. Many methods have been introduced to…

Methodology · Statistics 2022-07-12 Florian Gunsilius , Yuliang Xu

We study the problem of learning a directed acyclic graph from data generated according to an additive, non-linear structural equation model with Gaussian noise. We express each non-linear function through a basis expansion, and derive a…

Methodology · Statistics 2025-11-27 Xiaozhu Zhang , Nir Keret , Ali Shojaie , Armeen Taeb

In observational studies of treatment effects, matched samples are created so treated and control groups are similar in terms of observable covariates. Traditionally such matched samples consist of matched pairs. If a pair match fails to…

Methodology · Statistics 2014-10-22 Luke Keele , Sam Pimentel , Frank Yoon

We consider a bilevel continuous knapsack problem where the leader controls the capacity of the knapsack, while the follower chooses a feasible packing maximizing his own profit. The leader's aim is to optimize a linear objective function…

Data Structures and Algorithms · Computer Science 2022-07-19 Christoph Buchheim , Dorothee Henke , Jannik Irmai