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In Kidney Exchange Programs (KEPs), each participating patient is registered together with an incompatible donor. Donors without an incompatible patient can also register. Then, KEPs typically maximize overall patient benefit through donor…

Optimization and Control · Mathematics 2025-03-04 William St-Arnaud , Margarida Carvalho , Golnoosh Farnadi

This paper introduces a new learning-based approach for approximately solving the Kidney-Exchange Problem (KEP), an NP-hard problem on graphs. The problem consists of, given a pool of kidney donors and patients waiting for kidney donations,…

Machine Learning · Computer Science 2023-04-21 Pedro Foletto Pimenta , Pedro H. C. Avelar , Luis C. Lamb

The kidney paired donation (KPD) program provides an innovative solution to overcome incompatibility challenges in kidney transplants by matching incompatible donor-patient pairs and facilitating kidney exchanges. To address unequal access…

Methodology · Statistics 2026-01-21 Mingrui Zhang , Xiaowu Dai , Lexin Li

The efficient and fair allocation of limited resources is a classical problem in economics and computer science. In kidney exchanges, a central market maker allocates living kidney donors to patients in need of an organ. Patients and donors…

Artificial Intelligence · Computer Science 2020-05-21 Rachel Freedman , Jana Schaich Borg , Walter Sinnott-Armstrong , John P. Dickerson , Vincent Conitzer

AI algorithms increasingly make decisions that impact entire groups of humans. Since humans tend to hold varying and even conflicting preferences, AI algorithms responsible for making decisions on behalf of such groups encounter the problem…

Artificial Intelligence · Computer Science 2020-06-18 Rachel Freedman

Kidney exchange is a transplant modality that has provided new opportunities for living kidney donation in many countries around the world since 1991. It has been extensively studied from an Operational Research (OR) perspective since 2004.…

Data Structures and Algorithms · Computer Science 2025-09-03 Mathijs Barkel , Rachael Colley , Maxence Delorme , David Manlove , William Pettersson

Kidney transplants are sharply overdemanded in the United States. A recent innovation to address organ shortages is a kidney exchange, in which willing but medically incompatible patient-donor pairs swap donors so that two successful…

Computer Science and Game Theory · Computer Science 2019-12-24 Irena Gao

Kidney Exchange Programs (KEPs) promote access to living donor trans- plantation for patients suffering from end stage renal disease. The HLA compatibility between transplant recipients and donors plays an important role when solving the…

Optimization and Control · Mathematics 2025-10-17 Valentina Peralta Clarke , Hans de Ferrante , Francisco Perez Galarce , Joris van de Klundert

Current kidney exchange pools are of moderate size and thin, as they consist of many highly sensitized patients. Creating a thicker pool can be done by waiting for many pairs to arrive. We analyze a simple class of matching algorithms that…

Data Structures and Algorithms · Computer Science 2013-04-03 Itai Ashlagi , Patrick Jaillet , Vahideh H. Manshadi

Kidney exchange programs have substantially increased transplantation rates but also raise critical concerns about fairness in organ allocation. We propose a novel framework leveraging Data Envelopment Analysis (DEA) to evaluate multiple…

Computers and Society · Computer Science 2025-12-09 Ali Kaazempur-Mofrad , Xiaowu Dai

We study the problem of parameter estimation based on infection data from an epidemic outbreak on a graph. We assume that successive infections occur via contagion; i.e., transmissions can only spread across existing directed edges in the…

Statistics Theory · Mathematics 2018-06-15 Justin Khim , Po-Ling Loh

The feeder reconfiguration problem chooses the on/off status of the switches in a distribution network in order to minimize a certain cost such as power loss. It is a mixed integer nonlinear program and hence hard to solve. A popular…

Optimization and Control · Mathematics 2015-12-22 Qiuyu Peng , Steven H. Low

Kidney Exchange Programmes (KEPs) facilitate the exchange of kidneys, and larger pools of recipient-donor pairs tend to yield proportionally more transplants, leading to the proposal of international KEPs (IKEPs). However, as studied by…

Computer Science and Game Theory · Computer Science 2025-06-06 Rachael Colley , David Manlove , Daniel Paulusma , Mengxiao Zhang

We consider multi-item exchange markets in which agents want to receive one of their target bundles of resources. The model encompasses well-studied markets for kidney exchange, lung exchange, and multi-organ exchange. We identify a general…

Computer Science and Game Theory · Computer Science 2020-07-10 Haris Aziz

To this day, there are still some countries where the exchange of kidneys between multiple incompatible patient-donor pairs is restricted by law. Typically, legal regulations in this context are put in place to prohibit coercion and…

Cryptography and Security · Computer Science 2022-06-03 Malte Breuer , Ulrike Meyer , Susanne Wetzel

Balancing fairness and efficiency in resource allocation is a classical economic and computational problem. The price of fairness measures the worst-case loss of economic efficiency when using an inefficient but fair allocation rule; for…

Computer Science and Game Theory · Computer Science 2017-09-11 Duncan C. McElfresh , John P. Dickerson

Recently, an intriguing class of non-convex optimization problems has emerged in the context of learning directed acyclic graphs (DAGs). These problems involve minimizing a given loss or score function, subject to a non-convex continuous…

Machine Learning · Statistics 2023-05-30 Chang Deng , Kevin Bello , Bryon Aragam , Pradeep Ravikumar

Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can…

Machine Learning · Computer Science 2022-11-07 Zhipeng Huang , Kevin S. Xu

We consider the minimum spanning tree problem in a setting where the edge weights are stochastic from unknown distributions, and the only available information is a single sample of each edge's weight distribution. In this setting, we…

Data Structures and Algorithms · Computer Science 2024-09-25 Ruben Hoeksma , Gavin Speek , Marc Uetz

In the stochastic matching problem, we are given a general (not necessarily bipartite) graph $G(V,E)$, where each edge in $E$ is realized with some constant probability $p > 0$ and the goal is to compute a bounded-degree (bounded by a…

Data Structures and Algorithms · Computer Science 2017-05-08 Sepehr Assadi , Sanjeev Khanna , Yang Li