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Supervised causal learning has shown promise in causal discovery, yet it often struggles with generalization across diverse interventional settings, particularly when intervention targets are unknown. To address this, we propose TICL…

Machine Learning · Computer Science 2026-02-24 Wei Chen , Rui Ding , Bojun Huang , Yang Zhang , Qiang Fu , Yuxuan Liang , Han Shi , Dongmei Zhang

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Causal Bayesian networks have become a powerful technology for reasoning under uncertainty in areas that require transparency and explainability, by relying on causal assumptions that enable us to simulate hypothetical interventions. The…

Artificial Intelligence · Computer Science 2023-03-14 Anthony C. Constantinou , Zhigao Guo , Neville K. Kitson

Identifying causal relations is crucial for a variety of downstream tasks. In additional to observational data, background knowledge (BK), which could be attained from human expertise or experiments, is usually introduced for uncovering…

Artificial Intelligence · Computer Science 2024-07-23 Tian-Zuo Wang , Lue Tao , Zhi-Hua Zhou

Multiple chronic conditions (MCC) are one of the biggest challenges of modern times. The evolution of MCC follows a complex stochastic process that is influenced by a variety of risk factors, ranging from pre-existing conditions to…

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple…

Machine Learning · Computer Science 2025-03-17 Omar Costilla-Reyes , Morgan Talbot

We investigate whether temporal embedding models trained on longitudinal electronic health records can learn clinically meaningful representations without compromising predictive performance, and how architectural choices affect embedding…

Machine Learning · Computer Science 2026-04-17 Aditya Kumar , Mario A. Cypko , Oliver Amft

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Artificial Intelligence · Computer Science 2016-11-16 Pranjul Yadav , Lisiane Prunelli , Alexander Hoff , Michael Steinbach , Bonnie Westra , Vipin Kumar , Gyorgy Simon

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

Machine Learning · Computer Science 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

Chronic diseases are long-term, manageable, yet typically incurable conditions, highlighting the need for effective preventive strategies. Machine learning has been widely used to assess individual risk for chronic diseases. However, many…

Machine Learning · Computer Science 2025-06-24 Minh Le , Khoi Ton

Integrating expert knowledge, e.g. from large language models, into causal discovery algorithms can be challenging when the knowledge is not guaranteed to be correct. Expert recommendations may contradict data-driven results, and their…

Understanding causal dependencies in observational data is critical for informing decision-making. These relationships are often modeled as Bayesian Networks (BNs) and Directed Acyclic Graphs (DAGs). Existing methods, such as NOTEARS and…

Machine Learning · Computer Science 2026-04-03 Hao Zhu , Di Zhou , Donna Slonim

Causal discovery from observational data is pivotal for deciphering complex relationships. Causal Structure Learning (CSL), which focuses on deriving causal Directed Acyclic Graphs (DAGs) from data, faces challenges due to vast DAG spaces…

Artificial Intelligence · Computer Science 2023-11-21 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Huanhuan Chen

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Current grading systems based on imaging biomarkers only coarsely group disease stages into broad categories and are unable to predict future disease…

Modularity is a compelling solution to continual learning (CL), the problem of modeling sequences of related tasks. Learning and then composing modules to solve different tasks provides an abstraction to address the principal challenges of…

Machine Learning · Computer Science 2021-11-16 Oleksiy Ostapenko , Pau Rodriguez , Massimo Caccia , Laurent Charlin

Discovering the underlying Directed Acyclic Graph (DAG) from time series observational data is highly challenging due to the dynamic nature and complex nonlinear interactions between variables. Existing methods typically search for the…

Machine Learning · Computer Science 2025-03-21 Jiajun Zhang , Boyang Qiang , Xiaoyu Guo , Weiwei Xing , Yue Cheng , Witold Pedrycz

Motivation: Algorithms that discover variables which are causally related to a target may inform the design of experiments. With observational gene expression data, many methods discover causal variables by measuring each variable's degree…

Quantitative Methods · Quantitative Biology 2014-07-30 Eric V. Strobl , Shyam Visweswaran

Early prediction of mortality and length of stay(LOS) of a patient is vital for saving a patient's life and management of hospital resources. Availability of electronic health records(EHR) makes a huge impact on the healthcare domain and…

Machine Learning · Computer Science 2020-12-01 Batuhan Bardak , Mehmet Tan

LLMs suffer from critical reasoning issues such as unfaithfulness, bias, and inconsistency, since they lack robust causal underpinnings and may rely on superficial correlations rather than genuine understanding. Successive LRMs have emerged…

Artificial Intelligence · Computer Science 2025-09-23 Zhizhang FU , Guangsheng Bao , Hongbo Zhang , Chenkai Hu , Yue Zhang