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Limited DXA access hinders osteoporosis screening. This proof-of-concept study proposes using widely available knee X-rays for opportunistic Bone Mineral Density (BMD) estimation via deep learning, emphasizing robust uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Long Hui , Wai Lok Yeung

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

Tuberculosis (TB) remains a global health threat, ranking among the leading causes of mortality worldwide. In this context, machine learning (ML) has emerged as a transformative force, providing innovative solutions to the complexities…

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review…

Machine Learning · Computer Science 2023-05-29 Farida Mohsen , Hamada R. H. Al-Absi , Noha A. Yousri , Nady El Hajj , Zubair Shah

The prevalence of diabetic retinopathy (DR) has reached 34.6% worldwide and is a major cause of blindness among middle-aged diabetic patients. Regular DR screening using fundus photography helps detect its complications and prevent its…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Fahman Saeed , Muhammad Hussain , Hatim A Aboalsamh , Fadwa Al Adel , Adi Mohammed Al Owaifeer

Learning causal relationships solely from observational data often fails to reveal the underlying causal mechanisms due to the vast search space of possible causal graphs, which can grow exponentially, especially for greedy algorithms using…

Artificial Intelligence · Computer Science 2024-07-09 Uzma Hasan , Md Osman Gani

Chronic Kidney Disease (CKD) has infected almost 800 million people around the world. Around 1.7 million people die each year because of it. Detecting CKD in the initial stage is essential for saving millions of lives. Many researchers have…

Machine Learning · Computer Science 2022-03-04 Md. Taufiqul Haque Khan Tusar , Md. Touhidul Islam , Foyjul Islam Raju

Background: Automatic extraction of chemical-disease relations (CDR) from unstructured text is of essential importance for disease treatment and drug development. Meanwhile, biomedical experts have built many highly-structured knowledge…

Computation and Language · Computer Science 2019-12-24 Huiwei Zhou , Chengkun Lang , Zhuang Liu , Shixian Ning , Yingyu Lin , Lei Du

Causal discovery from time series is critical for many real-world applications, such as tracing the root causes of anomalies. Existing approaches typically rely on dataset-specific optimization, making it difficult to transfer their causal…

Machine Learning · Computer Science 2026-05-27 Biao Ouyang , Tengxue Zhang , Zhihao Zhuang , Yang Shu , Chenjuan Guo , Bin Yang

As language models (LMs) deliver increasing performance on a range of NLP tasks, probing classifiers have become an indispensable technique in the effort to better understand their inner workings. A typical setup involves (1) defining an…

Computation and Language · Computer Science 2024-08-01 Charles Jin , Martin Rinard

Cognitive Diagnosis Models (CDMs) are a special family of discrete latent variable models that are widely used in modern educational, psychological, social and biological sciences. A key component of CDMs is a binary $Q$-matrix…

Methodology · Statistics 2025-01-08 Chenchen Ma , Gongjun Xu

Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy, which, in turn, is the leading cause of end-stage chronic kidney disease. The early identification of individuals at heightened risk of such…

Quantitative Methods · Quantitative Biology 2024-09-24 Davide Dei Cas , Barbara Di Camillo , Gian Paolo Fadini , Giovanni Sparacino , Enrico Longato

Academic advances of AI models in high-precision domains, like healthcare, need to be made explainable in order to enhance real-world adoption. Our past studies and ongoing interactions indicate that medical experts can use AI systems with…

Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

Methodology · Statistics 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey

Chronic Kidney Disease (CKD) is one of the widespread Chronic diseases with no known ultimo cure and high morbidity. Research demonstrates that progressive Chronic Kidney Disease (CKD) is a heterogeneous disorder that significantly impacts…

Machine Learning · Computer Science 2025-01-28 K M Tawsik Jawad , Anusha Verma , Fathi Amsaad , Lamia Ashraf

Mainstream methods for Legal Judgment Prediction (LJP) based on Pre-trained Language Models (PLMs) heavily rely on the statistical correlation between case facts and judgment results. This paradigm lacks explicit modeling of legal…

Computation and Language · Computer Science 2026-03-13 Yuzhi Liang , Lixiang Ma , Xinrong Zhu

Causal machine learning (ML) recovers graphical structures that inform us about potential cause-and-effect relationships. Most progress has focused on cross-sectional data with no explicit time order, whereas recovering causal structures…

Machine Learning · Computer Science 2026-05-11 Bruno Petrungaro , Anthony C. Constantinou

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Coronary Artery Disease (CAD) results from plaque deposit in a coronary artery. Early diagnosis is imperative, so a non-invasive detection method is being developed to identify acoustic signals caused by partial occlusions in the artery.…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Bansi Mandalia , Steve Greenwald , Simon Shaw , Gregory Slabaugh

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo