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Background and objective: Diabetes is a chronic pathology which is affecting more and more people over the years. It gives rise to a large number of deaths each year. Furthermore, many people living with the disease do not realize the…

Despite the wide adoption of Large Language Models (LLM)s, clinical decision support systems face a critical challenge: achieving high predictive accuracy while generating explanations aligned with the predictions. Current approaches suffer…

Artificial Intelligence · Computer Science 2026-05-07 H M Quamran Hasan , Housam Khalifa Bashier , Jiayi Dai , Mi-Young Kim , Randy Goebel

Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

Personalized medicine based on medical images, including predicting future individualized clinical disease progression and treatment response, would have an enormous impact on healthcare and drug development, particularly for diseases (e.g.…

Artificial Intelligence · Computer Science 2024-06-19 Joshua Durso-Finley , Berardino Barile , Jean-Pierre Falet , Douglas L. Arnold , Nick Pawlowski , Tal Arbel

To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…

Machine Learning · Computer Science 2021-05-19 Jeremy Beauchamp , Razvan Bunescu , Cindy Marling , Zhongen Li , Chang Liu

Causal discovery is becoming a key part in medical AI research. These methods can enhance healthcare by identifying causal links between biomarkers, demographics, treatments and outcomes. They can aid medical professionals in choosing more…

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

Discovering causal structures among latent factors from observed data is a particularly challenging problem. Despite some efforts for this problem, existing methods focus on the single-domain data only. In this paper, we propose…

Machine Learning · Computer Science 2022-04-26 Yan Zeng , Shohei Shimizu , Ruichu Cai , Feng Xie , Michio Yamamoto , Zhifeng Hao

The safe deployment of large language models (LLMs) in high-stakes fields like biomedicine, requires them to be able to reason about cause and effect. We investigate this ability by testing 13 open-source LLMs on a fundamental task:…

Computation and Language · Computer Science 2026-03-13 Sydney Anuyah , Sneha Shajee-Mohan , Ankit-Singh Chauhan , Sunandan Chakraborty

With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we…

Computers and Society · Computer Science 2024-04-10 Tu Nguyen , Markus Rokicki

Diabetic Retinopathy (DR) is a serious and common complication of diabetes, caused by prolonged high blood sugar levels that damage the small retinal blood vessels. If left untreated, DR can progress to retinal vein occlusion and stimulate…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Mohammad Reza Yousefi , Ali Bakrani , Amin Dehghani

Long-term action recognition (LTAR) is challenging due to extended temporal spans with complex atomic action correlations and visual confounders. Although vision-language models (VLMs) have shown promise, they often rely on statistical…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Xu Shaowu , Jia Xibin , Gao Junyu , Sun Qianmei , Chang Jing , Fan Chao

Structural causal models (SCMs) provide a principled approach to identifying causation from observational and experimental data in disciplines ranging from economics to medicine. However, SCMs, which is typically represented as graphical…

Causal discovery (CD) plays a pivotal role in numerous scientific fields by clarifying the causal relationships that underlie phenomena observed in diverse disciplines. Despite significant advancements in CD algorithms that enhance bias and…

Machine Learning · Computer Science 2025-03-25 Khadija Zanna , Akane Sano

Latent variables pose a fundamental challenge to causal discovery and inference. Conventional local methods focus on direct neighbors but fail to provide macro level insights. Cluster level methods enable macro causal reasoning but either…

Machine Learning · Computer Science 2026-04-27 Zongyu Li

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

Machine Learning · Statistics 2017-10-31 Dustin Tran , David M. Blei

Most existing causal discovery methods rely on the assumption of no latent confounders, limiting their applicability in solving real-life problems. In this paper, we introduce a novel, versatile framework for causal discovery that…

Machine Learning · Computer Science 2023-12-19 Xinshuai Dong , Biwei Huang , Ignavier Ng , Xiangchen Song , Yujia Zheng , Songyao Jin , Roberto Legaspi , Peter Spirtes , Kun Zhang

The co-occurrence of multiple long-term conditions (MLTC), or multimorbidity, in an individual can reduce their lifespan and severely impact their quality of life. Exploring the longitudinal patterns, e.g. clusters, of disease accrual can…

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…