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The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

In this work, we devote ourselves to the challenging task of Unsupervised Multi-view Representation Learning (UMRL), which requires learning a unified feature representation from multiple views in an unsupervised manner. Existing UMRL…

Machine Learning · Computer Science 2023-03-09 Yiyang Zhou , Qinghai Zheng , Shunshun Bai , Jihua Zhu

Machine Learning (ML) is continuously permeating a growing amount of application domains. Generative AI such as Large Language Models (LLMs) also sees broad adoption to process multi-modal data such as text, images, audio, and video. While…

Machine Learning · Computer Science 2024-07-18 Pierre Lamart , Yinan Yu , Christian Berger

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

In this paper, we introduce ILLUME, a unified multimodal large language model (MLLM) that seamlessly integrates multimodal understanding and generation capabilities within a single large language model through a unified next-token…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chunwei Wang , Guansong Lu , Junwei Yang , Runhui Huang , Jianhua Han , Lu Hou , Wei Zhang , Hang Xu

Classification and identification of the materials lying over or beneath the Earth's surface have long been a fundamental but challenging research topic in geoscience and remote sensing (RS) and have garnered a growing concern owing to the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Danfeng Hong , Lianru Gao , Naoto Yokoya , Jing Yao , Jocelyn Chanussot , Qian Du , Bing Zhang

Composed Image Retrieval (CIR) is a complex task that aims to retrieve images based on a multimodal query. Typical training data consists of triplets containing a reference image, a textual description of desired modifications, and the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Chuong Huynh , Jinyu Yang , Ashish Tawari , Mubarak Shah , Son Tran , Raffay Hamid , Trishul Chilimbi , Abhinav Shrivastava

Large language models (LLMs) have substantially advanced machine learning research, including natural language processing, computer vision, data mining, etc., yet they still exhibit critical limitations in explainability, reliability,…

Machine Learning · Computer Science 2025-09-19 Xin Wang , Haoyang Li , Haibo Chen , Zeyang Zhang , Wenwu Zhu

Visual Similarity plays an important role in many computer vision applications. Deep metric learning (DML) is a powerful framework for learning such similarities which not only generalize from training data to identically distributed test…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Timo Milbich , Karsten Roth , Homanga Bharadhwaj , Samarth Sinha , Yoshua Bengio , Björn Ommer , Joseph Paul Cohen

Previous multimodal sentence representation learning methods have achieved impressive performance. However, most approaches focus on aligning images and text at a coarse level, facing two critical challenges:cross-modal misalignment bias…

Computation and Language · Computer Science 2025-07-02 Kang He , Yuzhe Ding , Haining Wang , Fei Li , Chong Teng , Donghong Ji

This paper proposes an introspective deep metric learning (IDML) framework for uncertainty-aware comparisons of images. Conventional deep metric learning methods produce confident semantic distances between images regardless of the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Wenzhao Zheng , Chengkun Wang , Jie Zhou , Jiwen Lu

Deep Metric Learning (DML) approaches learn to represent inputs to a lower-dimensional latent space such that the distance between representations in this space corresponds with a predefined notion of similarity. This paper investigates how…

Computer Vision and Pattern Recognition · Computer Science 2020-09-09 Niall O' Mahony , Sean Campbell , Anderson Carvalho , Lenka Krpalkova , Gustavo Velasco-Hernandez , Daniel Riordan , Joseph Walsh

Predicting patient features from single-cell data can help identify cellular states implicated in health and disease. Linear models and average cell type expressions are typically favored for this task for their efficiency and robustness,…

Machine Learning · Computer Science 2024-03-11 Jan P. Engelmann , Alessandro Palma , Jakub M. Tomczak , Fabian J. Theis , Francesco Paolo Casale

To address the challenge of utilizing patient data from other organ transplant centers (source cohorts) to improve survival time estimation and inference for a target center (target cohort) with limited samples and strict data-sharing…

Methodology · Statistics 2025-03-25 Hua Liu , Jiaqi Men , Shouxia Wang , Jinhong You , Jiguo Cao

Multi-modal data fusion has recently been shown promise in classification tasks in remote sensing. Optical data and radar data, two important yet intrinsically different data sources, are attracting more and more attention for potential…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Jingliang Hu , Danfeng Hong , Xiao Xiang Zhu

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

Machine Learning · Statistics 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Collaborative perception integrates multi-agent perspectives to enhance the sensing range and overcome occlusion issues. While existing multimodal approaches leverage complementary sensors to improve performance, they are highly prone to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Jiageng Wen , Shengjie Zhao , Bing Li , Jiafeng Huang , Kenan Ye , Hao Deng

Despite the recent success of Multimodal Foundation Models (FMs), their reliance on massive paired datasets limits their applicability in low-data and rare-scenario settings where aligned data is scarce and expensive. A key bottleneck is…

Machine Learning · Computer Science 2026-05-14 Truong Pham , Anay Majee , Rishabh Iyer

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Computer-assisted diagnostic and prognostic systems of the future should be capable of simultaneously processing multimodal data. Multimodal deep learning (MDL), which involves the integration of multiple sources of data, such as images and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Zhaoyi Sun , Mingquan Lin , Qingqing Zhu , Qianqian Xie , Fei Wang , Zhiyong Lu , Yifan Peng
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