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Estimating output changes by input changes is the main task in causal analysis. In previous work, input and output Self-Organizing Maps (SOMs) were associated for causal analysis of multivariate and nonlinear data. Based on the association,…

Computer Vision and Pattern Recognition · Computer Science 2017-03-28 Younjin Chung , Joachim Gudmundsson , Masahiro Takatsuka

Multivariate spatial data plays an important role in computational science and engineering simulations. The potential features and hidden relationships in multivariate data can assist scientists to gain an in-depth understanding of a…

Human-Computer Interaction · Computer Science 2019-08-30 Xiangyang He , Yubo Tao , Qirui Wang , Hai Lin

As an important application of spatial databases in pathology imaging analysis, cross-comparing the spatial boundaries of a huge amount of segmented micro-anatomic objects demands extremely data- and compute-intensive operations, requiring…

Databases · Computer Science 2012-08-02 Kaibo Wang , Yin Huai , Rubao Lee , Fusheng Wang , Xiaodong Zhang , Joel H. Saltz

We present a visual analytics system for exploring group differences in tensor fields with respect to all six degrees of freedom that are inherent in symmetric second-order tensors. Our framework closely integrates quantitative analysis,…

Live-cell imaging (LCI) technology enables the detailed spatio-temporal characterization of living cells at the single-cell level, which is critical for advancing research in the life sciences, from biomedical applications to bioprocessing.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Johannes Seiffarth , Keitaro Kasahara , Michelle Bund , Benita Lückel , Richard D. Paul , Matthias Pesch , Lennart Witting , Michael Bott , Dietrich Kohlheyer , Katharina Nöh

Manually investigating sheet music collections is challenging for music analysts due to the magnitude and complexity of underlying features, structures, and contextual information. However, applying sophisticated algorithmic methods would…

Human-Computer Interaction · Computer Science 2022-03-25 Matthias Miller , Julius Rauscher , Daniel A. Keim , Mennatallah El-Assady

Vision-based 3D occupancy prediction is significantly challenged by the inherent limitations of monocular vision in depth estimation. This paper introduces CVT-Occ, a novel approach that leverages temporal fusion through the geometric…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Zhangchen Ye , Tao Jiang , Chenfeng Xu , Yiming Li , Hang Zhao

The scalability of a particular visualization approach is limited by the ability for people to discern differences between plots made with different datasets. Ideally, when the data changes, the visualization changes in perceptible ways.…

Human-Computer Interaction · Computer Science 2019-07-29 Rafael Veras , Christopher Collins

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Optical flow, inspired by the mechanisms of biological visual systems, calculates spatial motion vectors within visual scenes that are necessary for enabling robotics to excel in complex and dynamic working environments. However, current…

The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics…

Quantitative Methods · Quantitative Biology 2024-07-15 James C. Kosmopoulos , Karthik Anantharaman

In several environmental applications data are functions of time, essentially con- tinuous, observed and recorded discretely, and spatially correlated. Most of the methods for analyzing such data are extensions of spatial statistical tools…

Methodology · Statistics 2011-06-28 Elvira Romano , Antonio Balzanella , Rosanna Verde

Combining clinical and omics data can improve both daily clinical routines and research to gain more insights into complex medical procedures. We present the results of our first phase in a multi-year collaboration with analysts and…

Human-Computer Interaction · Computer Science 2023-09-25 Markus Höhn , Hendrik Lücke-Tieke , Jan Burmeister , Jörn Kohlhammer

In order to find previously unknown subgroups in biomedical data and generate testable hypotheses, visually guided exploratory analysis can be of tremendous importance. In this paper we propose a new dissimilarity measure that can be used…

Applications · Statistics 2011-12-01 Charlotte Soneson , Magnus Fontes

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Although digital methods have significantly advanced morphology, practitioners are still challenged to understand and process tomographic specimen data. As automated processing of fossil data remains insufficient, morphologists still engage…

Human-Computer Interaction · Computer Science 2024-09-27 Lucas Siqueira Rodrigues , Thomas Kosch , John Nyakatura , Stefan Zachow , Johann Habakuk Israel

Recent advances in single cell sequencing and multi-omics techniques have significantly improved our understanding of biological phenomena and our capacity to model them. Despite combined capture of data modalities showing similar progress,…

Molecular Networks · Quantitative Biology 2025-03-13 Marcello Barylli , Joyaditya Saha , Tineke E. Buffart , Jan Koster , Kristiaan J. Lenos , Louis Vermeulen , Vivek M. Sheraton

State space models (SSMs) have recently emerged as an alternative to transformers due to their unique ability of modeling global relationships in text with linear complexity. However, their success in vision tasks has been limited due to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Kunal Mahatha , Ali Bahri , Pierre Marza , Sahar Dastani , Maria Vakalopoulou , Stergios Christodoulidis , Jose Dolz , Christian Desrosiers

Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

Mass spectrometry (MS) based single-cell proteomics (SCP) explores cellular heterogeneity by focusing on the functional effectors of the cells - proteins. However, extracting meaningful biological information from MS data is far from…

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