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One major bottleneck in the ongoing COVID-19 pandemic is the limited number of critical care beds. Due to the dynamic development of infections and the time lag between when patients are infected and when a proportion of them enters an…

Populations and Evolution · Quantitative Biology 2020-07-28 Matthias Ritter , Derek V. M. Ott , Friedemann Paul , John-Dylan Haynes , Kerstin Ritter

We examine the age-structured SIR model, a variant of the classical Susceptible-Infected-Recovered (SIR) model of epidemic propagation, in the context of COVID-19. In doing so, we provide a theoretical basis for the model, perform an…

Optimization and Control · Mathematics 2022-03-11 Rohit Parasnis , Ryosuke Kato , Amol Sakhale , Massimo Franceschetti , Behrouz Touri

Over the past two decades there has been a number of global outbreaks of viral diseases. This has accelerated the efforts to model and forecast the disease spreading, in order to find ways to confine the spreading regionally and between…

Physics and Society · Physics 2020-07-22 Rafael A. Barrio , Kimmo K. Kaski , Gudmundur G. Haraldsson , Thor Aspelund , Tzipe Govezensky

A reasonable prediction of infectious diseases transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized…

Populations and Evolution · Quantitative Biology 2021-02-23 Yuxuan Zhang , Chen Gong , Dawei Li , Zhi-Wei Wang , Shengda D Pu , Alex W Robertson , Hong Yu , John Parrington

We have established a novel mathematical model that considers various aspects of the spreading of the virus, including, the transmission based on being in the latent period, environment to human transmission, governmental decisions, and…

Quantitative Methods · Quantitative Biology 2020-08-31 Kamran Soltani , Ghader Rezazadeh

While image analysis of chest computed tomography (CT) for COVID-19 diagnosis has been intensively studied, little work has been performed for image-based patient outcome prediction. Management of high-risk patients with early intervention…

In this study, we construct a series of evolving epidemic networks by measuring the correlations of daily COVID-19 cases time series among 3,105 counties in the United States. Remarkably, through quantitative analysis of the spatial…

Physics and Society · Physics 2024-01-24 Jiarui Dong , Guanghao Ran

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

Methodology · Statistics 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

COVID-19--a viral infectious disease--has quickly emerged as a global pandemic infecting millions of people with a significant number of deaths across the globe. The symptoms of this disease vary widely. Depending on the symptoms an…

Populations and Evolution · Quantitative Biology 2020-07-23 Madhab Barman , Snigdhashree Nayak , Manoj K. Yadav , Soumyendu Raha , Nachiketa Mishra

The ongoing novel coronavirus epidemic has been announced a pandemic by the World Health Organization on March 11, 2020, and the Govt. of India has declared a nationwide lockdown from March 25, 2020, to prevent community transmission of…

Populations and Evolution · Quantitative Biology 2020-08-26 Subhas Khajanchi , Kankan Sarkar

For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

Populations and Evolution · Quantitative Biology 2020-04-15 Günter Bärwolff

The study of infectious disease epidemiology for multi-type disease pathogens requires modelling techniques that account for the complex interactions existing between strains across geography and time. In this paper, we propose a novel…

Methodology · Statistics 2026-05-06 Matthew Adeoye , Simon E. F. Spencer , Xavier Didelot

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

We propose an epidemiological model using an adaptive dynamic three compartment (with four states) SIR(D) model. Our approach is similar to non-parametric curve fitting in spirit and automatically adapts to key external factors, such as…

Applications · Statistics 2020-09-14 Madhuchhanda Bhattacharjee , Arup Bose

The 2019 Novel Corona virus infection (COVID 19) is an ongoing public health emergency of international focus. Significant gaps persist in our knowledge of COVID 19 epidemiology, transmission dynamics, investigation tools and management,…

Physics and Society · Physics 2020-12-01 Anca Radulescu , Cassandra Williams , Kieran Cavanagh

The severe acute respiratory syndrome COVID-19 has been in the center of the ongoing global health crisis in 2020. The high prevalence of mild cases facilitates sub-notification outside hospital environments and the number of those who are…

Populations and Evolution · Quantitative Biology 2021-05-26 Gilberto Nakamura , Basil Grammaticos , Christophe Deroulers , Mathilde Badoual

A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric,…

Methodology · Statistics 2024-02-01 Maria Pedrosa-Laza , Ana López-Cheda , Ricardo Cao

We develop a novel hybrid epidemiological model and a specific methodology for its calibration to distinguish and assess the impact of mobility restrictions (given by Apple's mobility trends data) from other complementary non-pharmaceutical…

Populations and Evolution · Quantitative Biology 2020-09-30 Victor Hugo Grisales Diaz , Oscar Andres Prado-Rubio , Mark J. Willis