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Assessing uncertainty is an important step towards ensuring the safety and reliability of machine learning systems. Existing uncertainty estimation techniques may fail when their modeling assumptions are not met, e.g. when the data…

Machine Learning · Computer Science 2017-01-24 Volodymyr Kuleshov , Stefano Ermon

Accurate segmentation of pediatric brain tumors in multi-parametric magnetic resonance imaging (mpMRI) is critical for diagnosis, treatment planning, and monitoring, yet faces unique challenges due to limited data, high anatomical…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Xiaolong Li , Zhi-Qin John Xu , Yan Ren , Tianming Qiu , Xiaowen Wang

The uncertainty quantifications of theoretical results are of great importance to make meaningful comparisons of those results with experimental data and to make predictions in experimentally unknown regions. By quantifying uncertainties,…

Nuclear Theory · Physics 2018-12-10 Sota Yoshida , Noritaka Shimizu , Tomoaki Togashi , Takaharu Otsuka

Medical image segmentation, particularly in the context of ultrasound data, is a crucial aspect of computer vision and medical imaging. This paper delves into the complexities of uncertainty in the segmentation process, focusing on fetal…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Shuge Lei

We propose an optimized U-Net architecture for a brain tumor segmentation task in the BraTS21 challenge. To find the optimal model architecture and the learning schedule, we have run an extensive ablation study to test: deep supervision…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Michał Futrega , Alexandre Milesi , Michal Marcinkiewicz , Pablo Ribalta

A myriad of algorithms for the automatic analysis of brain MR images is available to support clinicians in their decision-making. For brain tumor patients, the image acquisition time series typically starts with an already pathological…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Florian Kofler , Felix Meissen , Felix Steinbauer , Robert Graf , Stefan K Ehrlich , Annika Reinke , Eva Oswald , Diana Waldmannstetter , Florian Hoelzl , Izabela Horvath , Oezguen Turgut , Suprosanna Shit , Christina Bukas , Kaiyuan Yang , Johannes C. Paetzold , Ezequiel de da Rosa , Isra Mekki , Shankeeth Vinayahalingam , Hasan Kassem , Juexin Zhang , Ke Chen , Ying Weng , Alicia Durrer , Philippe C. Cattin , Julia Wolleb , M. S. Sadique , M. M. Rahman , W. Farzana , A. Temtam , K. M. Iftekharuddin , Maruf Adewole , Syed Muhammad Anwar , Ujjwal Baid , Anastasia Janas , Anahita Fathi Kazerooni , Dominic LaBella , Hongwei Bran Li , Ahmed W Moawad , Gian-Marco Conte , Keyvan Farahani , James Eddy , Micah Sheller , Sarthak Pati , Alexandros Karagyris , Alejandro Aristizabal , Timothy Bergquist , Verena Chung , Russell Takeshi Shinohara , Farouk Dako , Walter Wiggins , Zachary Reitman , Chunhao Wang , Xinyang Liu , Zhifan Jiang , Elaine Johanson , Zeke Meier , Ariana Familiar , Christos Davatzikos , John Freymann , Justin Kirby , Michel Bilello , Hassan M Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Rivka R Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-André Weber , Abhishek Mahajan , Suyash Mohan , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , Errol Colak , Priscila Crivellaro , Andras Jakab , Abiodun Fatade , Olubukola Omidiji , Rachel Akinola Lagos , O O Olatunji , Goldey Khanna , John Kirkpatrick , Michelle Alonso-Basanta , Arif Rashid , Miriam Bornhorst , Ali Nabavizadeh , Natasha Lepore , Joshua Palmer , Antonio Porras , Jake Albrecht , Udunna Anazodo , Mariam Aboian , Evan Calabrese , Jeffrey David Rudie , Marius George Linguraru , Juan Eugenio Iglesias , Koen Van Leemput , Spyridon Bakas , Benedikt Wiestler , Ivan Ezhov , Marie Piraud , Bjoern H Menze

Measurement of uncertainty of predictions from machine learning methods is important across scientific domains and applications. We present, to our knowledge, the first such technique that quantifies the uncertainty of predictions from a…

Machine Learning · Statistics 2022-04-04 Alex Hagen , Karl Pazdernik , Nicole LaHaye , Marjolein Oostrom

Brain tumor imaging has been part of the clinical routine for many years to perform non-invasive detection and grading of tumors. Tumor segmentation is a crucial step for managing primary brain tumors because it allows a volumetric analysis…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Masoomeh Rahimpour , Ahmed Radwan , Henri Vandermeulen , Stefan Sunaert , Karolien Goffin , Michel Koole

Recent advances in deep learning have significantly improved brain tumour segmentation techniques; however, the results still lack confidence and robustness as they solely consider image data without biophysical priors or pathological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Lipei Zhang , Yanqi Cheng , Lihao Liu , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Computer vision leveraging deep learning has achieved significant success in the last decade. Despite the promising performance of the existing deep models in the recent literature, the extent of models' reliability remains unknown.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-13 Seyed Omid Sajedi , Xiao Liang

Regression tasks, notably in safety-critical domains, require proper uncertainty quantification, yet the literature remains largely classification-focused. In this light, we introduce a family of measures for total, aleatoric, and epistemic…

Machine Learning · Computer Science 2025-10-30 Christopher Bülte , Yusuf Sale , Gitta Kutyniok , Eyke Hüllermeier

Segmentation of brain tumors is a critical step in treatment planning, yet manual segmentation is both time-consuming and subjective, relying heavily on the expertise of radiologists. In Sub-Saharan Africa, this challenge is magnified by…

Introducing accelerated reconstruction algorithms into clinical settings requires measures of uncertainty quantification that accurately assess the relevant uncertainty introduced by the reconstruction algorithm. Many currently deployed…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Luca L. C. Trautmann , Peter A. Wijeratne , Itamar Ronen , Ivor J. A. Simpson

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Qifei Cui , Xinyu Lu

Though deep learning has achieved advanced performance recently, it remains a challenging task in the field of medical imaging, as obtaining reliable labeled training data is time-consuming and expensive. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Yixin Wang , Yao Zhang , Jiang Tian , Cheng Zhong , Zhongchao Shi , Yang Zhang , Zhiqiang He

It is difficult to accurately label ambiguous and complex shaped targets manually by binary masks. The weakness of binary mask under-expression is highlighted in medical image segmentation, where blurring is prevalent. In the case of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Lin Wang , Lie Ju , Xin Wang , Wanji He , Donghao Zhang , Yelin Huang , Zhiwen Yang , Xuan Yao , Xin Zhao , Xiufen Ye , Zongyuan Ge

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Effective quantification of uncertainty is an essential and still missing step towards a greater adoption of deep-learning approaches in different applications, including mission-critical ones. In particular, investigations on the…

Machine Learning · Computer Science 2023-04-14 Marco Forgione , Dario Piga

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah