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Language Models (LMs) have shown promising performance in natural language generation. However, as LMs often generate incorrect or hallucinated responses, it is crucial to correctly quantify their uncertainty in responding to given inputs.…

Computation and Language · Computer Science 2024-09-17 Xinmeng Huang , Shuo Li , Mengxin Yu , Matteo Sesia , Hamed Hassani , Insup Lee , Osbert Bastani , Edgar Dobriban

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

The uncontrolled and unstructured growth of brain cells is known as brain tumor, which has one of the highest mortality rates among diseases from all types of cancers. Due to limited diagnostic and treatment capabilities, they pose…

Machine Learning · Computer Science 2024-04-02 PoTsang B. Huang , Muhammad Rizwan , Mehboob Ali

A U-Net based deep learning architecture is designed to segment brain tumors as they appear on various MRI modalities. Special emphasis is lent to the non-enhancing tumor compartment. The latter has not been considered anymore in recent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 T. Schaffer , A. Brawanski , S. Wein , A. M. Tomé , E. W. Lang

Brain Tumor Segmentation (BraTS) plays a critical role in clinical diagnosis, treatment planning, and monitoring the progression of brain tumors. However, due to the variability in tumor appearance, size, and intensity across different MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Hongjun Zhu , Jiaohang Huang , Kuo Chen , Xuehui Ying , Ying Qian

Clinical decision requires reasoning in the presence of imperfect data. DTs are a well-known decision support tool, owing to their interpretability, fundamental in safety-critical contexts such as medical diagnosis. However, learning DTs…

Purpose: In this paper, we investigate a framework for interactive brain tumor segmentation which, at its core, treats the problem of interactive brain tumor segmentation as a machine learning problem. Methods: This method has an advantage…

Computer Vision and Pattern Recognition · Computer Science 2016-05-20 Mohammad Havaei , Hugo Larochelle , Philippe Poulin , Pierre-Marc Jodoin

A brain tumor is a medical disorder faced by individuals of all demographics. Medically, it is described as the spread of non-essential cells close to or throughout the brain. Symptoms of this ailment include headaches, seizures, and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Adwaitt Pandya , Ozioma C. Oguine , Harita Bhargava , Shrikant Zade

In imaging inverse problems, one seeks to recover an image from missing/corrupted measurements. Because such problems are ill-posed, there is great motivation to quantify the uncertainty induced by the measurement-and-recovery process.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Jeffrey Wen , Rizwan Ahmad , Philip Schniter

Reliable uncertainty quantification is crucial for trustworthy decision-making and the deployment of AI models in medical imaging. While prior work has explored the ability of neural networks to quantify predictive, epistemic, and aleatoric…

Machine Learning · Statistics 2025-08-07 Simon Baur , Wojciech Samek , Jackie Ma

Identifying key pathological features in brain MRIs is crucial for the long-term survival of glioma patients. However, manual segmentation is time-consuming, requiring expert intervention and is susceptible to human error. Therefore,…

Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable image…

Explainability of black-box machine learning models is crucial, in particular when deployed in critical applications such as medicine or autonomous cars. Existing approaches produce explanations for the predictions of models, however, how…

Machine Learning · Computer Science 2021-11-18 Jonas Schulz , Rafael Poyiadzi , Raul Santos-Rodriguez

Accurately estimating uncertainties in neural network predictions is of great importance in building trusted DNNs-based models, and there is an increasing interest in providing accurate uncertainty estimation on many tasks, such as security…

Machine Learning · Computer Science 2020-07-14 Yukun Ding , Jinglan Liu , Jinjun Xiong , Yiyu Shi

Brain cancer can be very fatal, but chances of survival increase through early detection and treatment. Doctors use Magnetic Resonance Imaging (MRI) to detect and locate tumors in the brain, and very carefully analyze scans to segment brain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Ryan Sherman

Deep Learning is the state-of-the-art technology for segmenting brain tumours. However, this requires a lot of high-quality data, which is difficult to obtain, especially in the medical field. Therefore, our solutions address this problem…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 André Ferreira , Naida Solak , Jianning Li , Philipp Dammann , Jens Kleesiek , Victor Alves , Jan Egger

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

Accurate delineation of the Clinical Target Volume (CTV) is essential for radiotherapy planning, yet remains time-consuming and difficult to assess, especially for complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI).…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ricardo Coimbra Brioso , Lorenzo Mondo , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

Uncertainty quantification is a key pillar of trustworthy machine learning. It enables safe reactions under unsafe inputs, like predicting only when the machine learning model detects sufficient evidence, discarding anomalous data, or…

Machine Learning · Computer Science 2024-08-27 Michael Kirchhof

TodevelopanovelUncertaintyQuantification (UQ) framework to estimate the uncertainty of patient survival models in the absence of ground truth, we developed and evaluated our approach based on a dataset of 1383 patients treated with…

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