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Chemical reaction systems are dynamical systems that arise in chemical engineering and systems biology. In this work, we consider the question of whether the minimal (in a precise sense) multistationary chemical reaction networks, which we…
Analog-to-digital converters (ADCs) allow physical signals to be processed using digital hardware. Their conversion consists of two stages: Sampling, which maps a continuous-time signal into discrete-time, and quantization, i.e.,…
The transport of macromolecules, such as DNA, through the cytoskeleton is critical to wide-ranging cellular processes from cytoplasmic streaming to transcription. The rigidity and steric hindrances imparted by the network of filaments…
As computational chemistry methods evolve, dynamic effects have been increasingly recognized to govern chemical reaction pathways in both organic and inorganic systems. Here, we introduce a committor-based workflow that integrates a…
Incorporating cells within active biomaterial scaffolds is a promising strategy to develop forefront materials that can autonomously sense, respond, and alter the scaffold in response to environmental cues or internal cell circuitry. Using…
The formation and regulation of macromolecular complexes provides the backbone of most cellular processes, including gene regulation and signal transduction. The inherent complexity of assembling macromolecular structures makes current…
Ratchet effects can arise for single or collectively interacting Brownian particles on an asymmetric substrate when a net dc transport is produced by an externally applied ac driving force or by periodically flashing the substrate.…
Cache-enabled Device-to-Device (D2D) communication is widely recognized as one of the key components of the emerging fifth generation (5G) cellular network architecture. However, conventional half-duplex (HD) transmission may not be…
Hybrid circuit and packet switching for data center networking (DCN) has received considerable research attention recently. A hybrid-switched DCN employs a much faster circuit switch that is reconfigurable with a nontrivial cost, and a much…
A mechanism of double strand breaking (DSB) in DNA due to the action of two electrons is considered. These are the electrons produced in the vicinity of DNA molecules due to ionization of water molecules with a consecutive emission of two…
Most binary superlattices created using DNA functionalization or other approaches rely on particle size differences to achieve compositional order and structural diversity. Here we study two-dimensional (2D) assembly of DNA-functionalized…
An easily implementable path solution algorithm for 2D spatial problems, based on excitable/programmable characteristics of a specific cellular nonlinear network (CNN) model is presented and numerically investigated. The network is a single…
A key challenge for AI is to build embodied systems that operate in dynamically changing environments. Such systems must adapt to changing task contexts and learn continuously. Although standard deep learning systems achieve state of the…
We show that discrete distributions on the $d$-dimensional non-negative integer lattice can be approximated arbitrarily well via the marginals of stationary distributions for various classes of stochastic chemical reaction networks. We…
Time-dependent multiphysics interactions that drive the energy transfer in electromechanical systems are poorly understood. We probe dielectric barrier discharge (DBD) with an external DC-augmented (DCA) field to reveal new mechanistic…
The construction of synthetic biochemical circuits is an essential step for developing quantitative understanding of information processing in natural organisms. Here, we report construction and analysis of an in vitro circuit with positive…
When dealing with deep neural network (DNN) applications on edge devices, continuously updating the model is important. Although updating a model with real incoming data is ideal, using all of them is not always feasible due to limits, such…
Renaturation of complementary single strands of DNA is one of the important processes that requires better understanding in the view of molecular biology and biological physics. Here we develop a stochastic dynamical model on the DNA…
Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing the network topologies that can…
In biochemical networks, complex dynamical features such as superlinear growth and oscillations are classically considered a consequence of autocatalysis. For the large class of parameter-rich kinetic models, which includes Generalized Mass…