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Motor-proteins are responsible for transport inside cells. Harnessing their activity is key towards developing new nano-technologies, or functional biomaterials. Cytoskeleton-like networks, recently tailored in vitro, result from the…

Soft Condensed Matter · Physics 2016-06-21 Pau Guillamat , Jordi Ignés-Mullol , Francesc Sagués

Active matter systems evade the constraints of thermal equilibrium, leading to the emergence of intriguing collective behavior. A paradigmatic example is given by motor-filament mixtures, where the motion of motor proteins drives alignment…

Soft Condensed Matter · Physics 2024-09-11 Filippo De Luca , Ivan Maryshev , Erwin Frey

The cytoskeleton protein actin assembles into large bundles when supporting stresses in the cell, but grows into a fine branched network to induce cell motion. Such self-organization processes are studied in artificial networks of…

Soft Condensed Matter · Physics 2018-06-13 Adar Sonn-Segev , Anne Bernheim-Groswasser , Yael Roichman

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

We explore the rheology predicted by a recently proposed constitutive model for jammed suspensions of soft elastic particles derived from particle-level dynamics [Cuny et al., Phys. Rev. Lett. 127, 218003 (2021)]. Our model predicts that…

Soft Condensed Matter · Physics 2022-01-06 Nicolas Cuny , Éric Bertin , Romain Mari

One of the most interesting phenomena in the soft-matter realm consists in the spontaneous formation of super-molecular structures (microphases) in condition of thermodynamic equilibrium. A simple mechanism responsible for this…

Soft Condensed Matter · Physics 2017-08-23 A. Imperio , D. Pini , L. Reatto

The process of polarization determines the head and tail of single cells. A mechanism of this kind frequently precedes the subsequent cell locomotion and it determines the direction of motion. The process of polarization has frequently been…

Biological Physics · Physics 2021-12-30 Eduardo Moreno , Sergio Alonso

Using novel micro-printing techniques, we develop a versatile experimental setup that allows us to study how lateral confinement tames the active flows and defect properties of the microtubule/kinesin active nematic system. We demonstrate…

Bundles of filaments and motors are central to contractility in cells. The classic example is striated muscle, where actomyosin contractility is mediated by highly organized sarcomeres which act as fundamental contractile units. However,…

Biological Physics · Physics 2012-06-12 Martin Lenz , Todd Thoresen , Margaret L. Gardel , Aaron R. Dinner

Molecular-motor generated active stresses drive the cytoskeleton away from equilibrium, endowing it with tunable mechanical properties that are essential for diverse functions such as cell division and motility[1-5]. Designing analogous…

We report structure formation in submonolayers of magnetic microparticles subjected to periodic electrostatic and magnetic excitations. Depending on the excitation parameters, we observe the formation of a rich variety of structures:…

Pattern Formation and Solitons · Physics 2009-11-10 A. Snezhko , I. S. Aranson , W. -K. Kwok

Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…

Soft Condensed Matter · Physics 2018-04-25 Silke Henkes , M. Cristina Marchetti , Rastko Sknepnek

Morphogenesis emerges from dynamic feedback among geometry, mechanics, and chemistry; however, disentangling these contributions in living systems remains challenging. Here, we focus on the interplay between geometry and mechanics by…

Motivated by the observation of highly unstable flowing states in suspensions of microtubules and kinesin, we analyze a model of mutually-propelled filaments suspended in a solvent. The system undergoes a mean-field isotropic-nematic…

Soft Condensed Matter · Physics 2015-05-30 L. Giomi , L. Mahadevan , B. Chakraborty , M. F. Hagan

While cell crawling on a solid surface is relatively well understood, and relies on substrate adhesion, some cells can also swim in the bulk, through mechanisms that are still largely unclear. Here, we propose a minimal model for in-bulk…

Soft Condensed Matter · Physics 2017-12-11 Thomas Le Goff , Benno Liebchen , Davide Marenduzzo

We present a model for the spontaneous formation of a striated pattern in polymerizing microtubule solutions. It describes the buckling of a single microtubule (MT) bundle within an elastic network formed by other similarly aligned and…

Biological Physics · Physics 2007-06-13 Yongxing Guo , Yifeng Liu , Jay X. Tang , James M. Valles

Important cellular processes, such as cell motility and cell division, are coordinated by cell polarity, which is determined by the non-uniform distribution of certain proteins. Such protein patterns form via an interplay of protein…

Biological Physics · Physics 2020-05-20 Manon C Wigbers , Fridtjof Brauns , Ching Yee Leung , Erwin Frey

The actin and microtubule cytoskeletons are vital structures for cell growth and development across all species. While individual molecular mechanisms underpinning actin and microtubule dynamics have been intensively studied, principles…

Active stresses in biological cells and tissues drive many developmental processes. However, increasing experimental evidence suggests that additional mechanical interactions with surrounding material can play a crucial role in guiding…

Soft Condensed Matter · Physics 2026-03-10 Douglas MacMyn Brown , Alexander Mietke

The paper addresses the underlying source of two forms of induced anisotropy in granular materials: contact orientation anisotropy and contact force anisotropy. A rational, mathematical structure is reviewed for the manner in which fabric…

Soft Condensed Matter · Physics 2019-01-23 Matthew R. Kuhn