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The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Monte Carlo simulation, experiment and continuum theory are used to examine the anchoring exhibited by a nematic liquid crystal at a patterned substrate comprising a periodic array of rectangles that, respectively, promote vertical and…

Soft Condensed Matter · Physics 2013-08-09 Candy Anquetil-Deck , Douglas J. Cleaver , Jonathan P. Bramble , Timothy J. Atherton

We develop a minimal hydrodynamic model, without an orientational order parameter, for assemblies of contractile swimmers encapsulated in a droplet of a binary-fluid emulsion. Our model uses two coupled scalar order parameters, $\phi$ and…

Soft Condensed Matter · Physics 2022-09-13 Nadia Bihari Padhan , Rahul Pandit

The cooperative binding of molecular agents onto a substrate is pervasive in living systems. To study whether a system shows cooperativity, one can rely on a fluctuation analysis of quantities such as the number of substrate-bound units and…

We review theoretical models of individual motility as well as collective dynamics and pattern formation of active particles. We focus on simple models of active dynamics with a particular emphasis on nonlinear and stochastic dynamics of…

Other Condensed Matter · Physics 2015-06-04 Pawel Romanczuk , Markus Bär , Werner Ebeling , Benjamin Lindner , Lutz Schimansky-Geier

We study the formation of spot patterns seen in a variety of bacterial species when the bacteria are subjected to oxidative stress due to hazardous byproducts of respiration. Our approach consists of coupling the cell density field to a…

Traditional top-down robotic design often lacks the adaptability needed to handle real-world complexities, prompting the need for more flexible approaches. Therefore, this study introduces a novel cellular plasticity model tailored for…

Robotics · Computer Science 2024-08-13 Trevor R. Smith , Thomas J. Smith , Nicholas S. Szczecinski , Sergiy Yakovenko , Yu Gu

A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…

Soft Condensed Matter · Physics 2026-03-17 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering process, such as active contraction of a network, from this…

Biological Physics · Physics 2024-08-22 Soichi Hirokawa , Heun Jin Lee , Rachel A Banks , Ana I Duarte , Bibi Najma , Matt Thomson , Rob Phillips

This work introduces a new theoretical model for active matter ("complementary-spins" or c-spins), exploring the interplay of positional and orientational order in mobile agents with rotational freedom, divided into two populations with…

Soft Condensed Matter · Physics 2025-11-20 Alessandro Scirè

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

The persistent motion of bacteria produces clusters with a stationary cluster size distribution (CSD). Here we develop a minimal model for bacteria in a narrow channel to assess the relative importance of motility diversity (i.e.…

Soft Condensed Matter · Physics 2020-11-19 Pablo de Castro , Saulo Diles , Rodrigo Soto , Peter Sollich

Cell crawling requires the generation of intracellular forces by the cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecules. Crawling cells show many features of excitable systems, such as…

Biological Physics · Physics 2020-06-02 Pierre Sens

We investigate the hydrodynamic stability and the formation of patterns in a continuum model of epithelial layers, able to account for the interplay between mechanical activity, lateral adhesion and the $6-$fold orientational order…

Soft Condensed Matter · Physics 2025-02-19 Josep-Maria Armengol-Collado , Leonardo Puggioni , Livio N. Carenza , Luca Giomi

The interaction of the actin cytoskeleton with cell-substrate adhesions is necessary for cell migration. While the trajectories of motile cells have a stochastic character, investigations of cell motility mechanisms rarely elaborate on the…

Quantitative Methods · Quantitative Biology 2019-03-21 Aydar Uatay

Dynamic instability in the cytoskeleton underlies a great many vital cellular processes. In neurons, it is thought to play a role in information processing and the establishment of synaptic connections. It is from this interneuronal…

Medical Physics · Physics 2019-12-19 Gweneth Andersen

We use a two-fluid model to study a confined mixture of an active nematic fluid and a passive isotropic fluid. We find that an extensile active fluid preferentially accumulates at a boundary if the anchoring is planar, whereas its boundary…

Soft Condensed Matter · Physics 2025-09-03 Saraswat Bhattacharyya , Julia M. Yeomans

Cluster formation of microscopic swimmers is key to the formation of biofilms and colonies, efficient motion and nutrient uptake, but, in the absence of other interactions, requires high swimmer concentrations to occur. Here we…

Soft Condensed Matter · Physics 2023-08-22 Solenn Riedel , Ludwig A. Hoffmann , Luca Giomi , Daniela J. Kraft

Several experiments have demonstrated the existence of an electro-mechanical effect in many biological tissues and hydrogels, and its actual influence on growth, migration, and pattern formation. Here, to model these interactions and…

Soft Condensed Matter · Physics 2020-07-07 Yangkun Du , Yipin Su , Chaofeng Lu , Weiqiu Chen , Michel Destrade