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We study the steady state of an assembly of microtubules in a confined volume, analogous to the situation inside a cell where the cell boundary forms a natural barrier to growth. We show that the dynamical equations for growing and…

Subcellular Processes · Quantitative Biology 2012-08-27 Bindu S. Govindan , William. B. Spillman,

Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

Soft Condensed Matter · Physics 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

Intracellular components explore the cytoplasm via active motor-driven transport in conjunction with passive diffusion. We model the motion of organelles in narrow tubular cells using analytical techniques and numerical simulations to study…

Biological Physics · Physics 2018-04-11 Saurabh Mogre , Elena F. Koslover

We consider two minimal models of active fluid droplets that exhibit complex dynamics including steady motion, deformation, rotation and oscillating motion. First we consider a droplet with a concentration of active contractile matter…

Soft Condensed Matter · Physics 2016-12-20 Carl A. Whitfield , Rhoda J. Hawkins

We study a minimal model of a crawling eukaryotic cell with a chemical polarity controlled by a reaction-diffusion mechanism describing Rho GTPase dynamics. The size, shape, and speed of the cell emerge from the combination of the chemical…

Biological Physics · Physics 2017-01-11 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel

Recent whole-brain calcium imaging recordings of the nematode C. elegans have demonstrated that neural activity is dominated by dynamics on a low-dimensional manifold that can be clustered according to behavioral states. Despite progress in…

Neurons and Cognition · Quantitative Biology 2020-02-05 Megan Morrison , Charles Fieseler , J. Nathan Kutz

Cellular patterns formed by self-organization of dislocations are a most conspicuous feature of dislocation microstructure evolution during plastic deformation. To elucidate the physical mechanisms underlying dislocation cell structure…

Materials Science · Physics 2020-07-20 Ronghai Wu , Michael Zaiser

We consider the influence of quenched disorder on the relaxational critical dynamics of a system characterized by a non-conserved order parameter coupled to the diffusive dynamics of a conserved scalar density (model C). Disorder leads to…

Disordered Systems and Neural Networks · Physics 2009-11-11 M. Dudka , R. Folk , Yu. Holovatch , G. Moser

Active nematics are microscopically driven liquid crystals that exhibit dynamical steady states characterized by the creation and annihilation of topological defects. Motivated by experimental realizations of such systems made of biopolymer…

Soft Condensed Matter · Physics 2018-09-05 Abhijeet Joshi , Elias Putzig , Aparna Baskaran , Michael Hagan

Turing instabilities for a two species reaction-diffusion systems is studied under anisotropic diffusion. More specifically, the diffusion constants which characterize the ability of the species to relocate in space are direction sensitive.…

Statistical Mechanics · Physics 2015-09-30 Daniel M. Busiello , Gwendoline Planchon , Malbor Asllani , Timoteo Carletti , Duccio Fanelli

We study a minimal cognitive flocking model, which assumes that the moving entities navigate using exclusively the available instantaneous visual information. The model consists of active particles, with no memory, that interact by a…

Biological Physics · Physics 2019-12-18 Lucas Barberis , Fernando Peruani

Collective behaviors such as swarming, chemical signaling, and clustering are fundamental to biological microorganisms, enabling hierarchical colony formation, coordinated motion, and enhanced nutrient accessibility crucial for their…

Soft Condensed Matter · Physics 2025-02-12 Sobiya Ashraf , Pawan Kumar , Prateek Dwivedi , Frédéric Blanc , Dipin Pillai , Rahul Mangal

Motivated by the formation of ring-like filament structures in the cortex of plant and animal cells, we study the dynamics of a two-dimensional layer of cytoskeletal filaments and motor proteins near a surface by a general continuum theory.…

Subcellular Processes · Quantitative Biology 2009-11-11 Alexander Zumdieck , Marco Cosentino Lagomarsino , Catalin Tanase , Karsten Kruse , Bela Mulder , Marileen Dogterom , Frank J"ulicher

Macromolecules can gain special properties by adopting knotted conformations, but engineering knotted macromolecules is a challenging task. Here we surprisingly observed that knotting can be very effectively produced in active polymers.…

Soft Condensed Matter · Physics 2024-12-10 Jia-Xiang Li , Song Wu , Li-Li Hao , Qun-Li Lei , Yu-Qiang Ma

Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends of neuronal MTs switch between growth and shrinking phases,…

Biological Physics · Physics 2025-07-11 Anna C. Nelson , Scott A. McKinley , Melissa M. Rolls , Maria-Veronica Ciocanel

Active tissues exhibit tension fluctuations that are correlated in space and time. We study a minimal overdamped surface model in which such fluctuations enter as a zero-mean, multiplicative modulation of the local surface tension. Although…

Soft Condensed Matter · Physics 2026-03-02 Matteo Ciarchi , Andriy Goychuk , Erwin Frey

Motivated by experimental results on the interplay between molecular motors and tau proteins, we extend lattice-based models of intracellular transport to include a second species of particle which locally influences the motor-filament…

Subcellular Processes · Quantitative Biology 2010-04-27 H. Grzeschik , R. J. Harris , L. Santen

Understanding physical rules underlying collective motions requires perturbation of controllable parameters in self-propelled particles. However, controlling parameters in animals is generally not easy, which makes collective behaviours of…

Biological Physics · Physics 2019-01-31 Takuma Sugi , Hiroshi Ito , Masaki Nishimura , Ken H. Nagai

An aster of microtubules is a set of flexible polar filaments with dynamic plus-ends, which irradiate from a common location at which the minus ends of the filaments are found. Processive soluble oligomeric motor complexes can bind…

Soft Condensed Matter · Physics 2007-05-23 Francois Nedelec

Active matter consists of self-propelled elements exhibits fascinating collective motions ranging from biological to artificial systems. Among wide varieties of active matter systems, reconstituted bio-filaments moving on molecular motor…

Soft Condensed Matter · Physics 2020-03-25 Sakurako Tanida , Ken'ya Furuta , Kaori Nishikawa , Tetsuya Hiraiwa , Hiroaki Kojima , Kazuhiro Oiwa , Masaki Sano
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