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Making decisions freely presupposes that there is some indeterminacy in the environment and in the decision making engine. The former is reflected on the behavioral changes due to communicating: few changes indicate rigid environments;…

Artificial Intelligence · Computer Science 2020-09-23 Luis A. Pineda

We consider a coupled linear system describing a thermoviscoelastic plate with hereditary effects. The system consists of a hyperbolic integrodifferential equation, governing the temperature, which is linearly coupled with the partial…

Analysis of PDEs · Mathematics 2008-10-10 Maurizio Grasselli , Jaime E. Munoz Rivera , Marco Squassina

Adaptive humoral immunity, from the physical perspective, can be regarded as the self-organization of the binding energy landscape of antibodies. In biological terms, the humoral immune system evolves and adapts its repertoire of antigen…

Other Quantitative Biology · Quantitative Biology 2025-09-15 Jozsef Prechl

Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs). This principle allows us to focus on the…

Numerical Analysis · Mathematics 2016-11-03 Guo-Wei Wei , Y. C. Zhou

This paper presents the computational methods of information cohomology applied to genetic expression in and in the companion paper and proposes its interpretations in terms of statistical physics and machine learning. In order to further…

Neurons and Cognition · Quantitative Biology 2019-07-16 Pierre Baudot

Three different approaches to derive mutual information via thermodynamics are presented where the temperature-dependent energy is given by: (a) $\beta \mathcal{E} = -\ln[P(X,Y)]$, (b) $\beta \mathcal{E} =-\ln[P(Y|X)]$ or (c) $\beta…

Statistical Mechanics · Physics 2010-03-24 Yitzhak Peleg , Hadar Efraim , Ori Shental , Ido Kanter

The neural networks of the brain are capable of learning statistical input regularities on the basis of synaptic learning, functional integration into increasingly larger, interconnected neural assemblies, and self organization. This self…

Robotics · Computer Science 2022-06-10 Birgitta Dresp-Langley

We consider the problem of defining free energy and other thermodynamic functions when the entropy is given as a general function of the probablity distribution, including that for non extensive forms. We find that the free energy, which is…

Statistical Mechanics · Physics 2007-11-07 Fariel Shafee

Configurational states that are to be associated, according to Goldstein, with the basins in the potential energy landscape cannot be characterized by any particular basin identifier such as the basin minima, the lowest barrier, the most…

Statistical Mechanics · Physics 2016-08-31 P. D. Gujrati , F. Semerianov

What is it about human brains that allows us to reason symbolically whereas most other animals cannot? There is evidence that dynamic binding, the ability to combine neurons into groups on the fly, is necessary for symbolic thought, but…

Neural and Evolutionary Computing · Computer Science 2025-08-22 John E. Hummel , Rachel F. Heaton

Human interactions are influenced by emotions, temperament, and affection, often conflicting with individuals' underlying preferences. Without explicit knowledge of those preferences, judging whether behaviour is appropriate becomes…

Computer Science and Game Theory · Computer Science 2025-11-05 Victor Villin , Christos Dimitrakakis

Estimating the free energy in molecular simulation requires, implicitly or explicitly, counting how many times the system is observed in a finite region. If the simulation is biased by an external potential, the weight of the configurations…

Chemical Physics · Physics 2021-12-22 Matteo Carli , Alessandro Laio

Cells are able to generate phenotypic diversity both during development and in response to stressful and changing environments, aiding survival. The biologically and medically vital process of a cell assuming a functionally important fate…

Cell Behavior · Quantitative Biology 2019-12-16 Ryan Kerr , Sara Jabbari , Iain G. Johnston

Biological molecular machines are bifunctional enzymes that catalyze two processes: one donating free energy and the other accepting it. Recent studies show that most protein enzymes have rich stochastic dynamics of transitions between the…

Biological Physics · Physics 2023-02-02 Michal Kurzynski , Przemyslaw Chelminiak

A time-dependent multiconfigurational self-consistent field theory is presented to describe the many-body dynamics of a gas of identical bosonic atoms confined to an external trapping potential at zero temperature from first principles. A…

Other Condensed Matter · Physics 2007-10-16 David J. Masiello , William P. Reinhardt

State-of-the-art neurosymbolic learning systems use probabilistic reasoning to guide neural networks towards predictions that conform to logical constraints over symbols. Many such systems assume that the probabilities of the considered…

Machine Learning · Statistics 2024-06-10 Emile van Krieken , Pasquale Minervini , Edoardo M. Ponti , Antonio Vergari

We introduce a constructive framework for assigning thermodynamic structure to an arbitrary data system from its measured microstates. Starting from an empirical distribution over configurations, we first infer a data-driven energy function…

Statistical Mechanics · Physics 2026-04-29 George-Rafael Domenikos , Lock Yue Chew , Victoria Leong

Recent experiments appear to have revealed the possibility of quantum entanglement between spatially separated human subjects. In addition, a similar condition might exist between basins containing human neurons adhering to printed circuit…

General Physics · Physics 2007-05-23 Fred H. Thaheld

We study learning problems in which the conditional distribution of the output given the input varies as a function of additional task variables. In varying-coefficient models with Gaussian process priors, a Gaussian process generates the…

Machine Learning · Computer Science 2015-10-15 Matthias Bussas , Christoph Sawade , Tobias Scheffer , Niels Landwehr

This work combines the free energy principle from cognitive neuroscience and the ensuing active inference dynamics with recent advances in variational inference in deep generative models, and evolution strategies to introduce the "deep…

Neurons and Cognition · Quantitative Biology 2018-10-24 Kai Ueltzhöffer