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Lymph node metastasis is one of the most significant diagnostic indicators in breast cancer, which is traditionally observed under the microscope by pathologists. In recent years, computerized histology diagnosis has become one of the most…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Huangjing Lin , Hao Chen , Qi Dou , Liansheng Wang , Jing Qin , Pheng-Ann Heng

Purpose: The goal is to develop a new architecture for computed tomography (CT) which is at an ultra-low-dose for developing countries, especially in rural areas. Methods: The proposed scheme is inspired by the recently developed…

Medical Physics · Physics 2013-12-23 Fenglin Liu , Hengyong Yu , Wenxiang Cong , Ge Wang

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-small cell lung cancer (NSCLC). While [$^{18}$F]FDG PET/CT is a standard tool for the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Fatih Aksu , Laura Ciuffetti , Francesco Di Feola , Filippo Ruffini , Giulia Romoli , Fabrizia Gelardi , Arturo Chiti , Valerio Guarrasi , Paolo Soda

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Obaidullah Rahman , Singanallur V. Venkatakrishnan , Luke Scime , Paul Brackman , Curtis Frederick , Ryan Dehoff , Vincent Paquit , Amirkoushyar Ziabari

Scanning transmission X-ray microscopy (STXM) is a nanoscale imaging technique that can utilize several powerful contrast mechanisms for the quantitative mapping of chemical and physical materials properties. Spatial resolutions down to…

Instrumentation and Detectors · Physics 2026-05-27 Simone Finizio , Benjamin Watts , Benedikt Rösner , Tim A. Butcher , Sebastian Wintz , Markus Weigand , Jörg Raabe

In the fields of nanoscience and nanotechnology, it is important to be able to functionalize surfaces chemically for a wide variety of applications. Scanning tunneling microscopes (STMs) are important instruments in this area used to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-25 Bui Kevin , Fauman Jacob , Kes David , Torres Mandiola Leticia , Ciomaga Adina , Salazar Ricardo , Bertozzi L. Andrea , Gilles Jerome , Guttentag I. Andrew , Weiss S. Paul

As Micro-CT technology continues to refine its characterization of material microstructures, industrial CT ultra-precision inspection is generating increasingly large datasets, necessitating solutions to the trade-off between accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Yipeng Yin , Rao Yao , Qingying Li , Dazhong Wang , Hong Zhou , Zhijun Fang , Jianing Chen , Longjie Qian , Mingyue Wu

This work presents a high-resolution X-ray microtomography system that uses commercial off-the-shelf (COTS) CMOS image sensors as direct detectors, relying on the sensor s intrinsic resolution to achieve tomographic reconstructions without…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Damian L. Corzi , Jose Lipovetzky , Fabricio Alcalde Bessia , German Mato , Andres Cicuttin , Maria L. Crespo , Martin Perez , Mariano Gomez Berisso

Microvascular anatomy is known to be involved in various neurological disorders. However, understanding these disorders is hindered by the lack of imaging modalities capable of capturing the comprehensive three-dimensional vascular network…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Etienne Chollet , Yaël Balbastre , Chiara Mauri , Caroline Magnain , Bruce Fischl , Hui Wang

Medical imaging modalities have revolutionized health-care approaches by offering a better understanding of the human anatomy. Discovery of x-rays allowed the exploiting of the micro-scaled information of human anatomy. Computed tomography…

Medical Physics · Physics 2018-09-18 Sanam Assili

The diagnostic quality of computed tomography (CT) scans is usually restricted by the induced patient dose, scan speed, and image quality. Sparse-angle tomographic scans reduce radiation exposure and accelerate data acquisition, but suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Fabian Wagner , Mareike Thies , Noah Maul , Laura Pfaff , Oliver Aust , Sabrina Pechmann , Christopher Syben , Andreas Maier

Scanning transmission electron microscopy is a common tool used to study the atomic structure of materials. It is an inherently multimodal tool allowing for the simultaneous acquisition of multiple information channels. Despite its…

Histopathology plays a pivotal role in medical diagnostics. In contrast to preparing permanent sections for histopathology, a time-consuming process, preparing frozen sections is significantly faster and can be performed during surgery,…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Elad Yoshai , Gil Goldinger , Miki Haifler , Natan T. Shaked

Texture-space shading (TSS) methods decouple shading and rasterization, allowing shading to be performed at a different framerate and spatial resolution than rasterization. TSS has many potential applications, including streaming shading…

Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Le Hou , Ayush Agarwal , Dimitris Samaras , Tahsin M. Kurc , Rajarsi R. Gupta , Joel H. Saltz

A radiograph visualizes the internal anatomy of a patient through the use of X-ray, which projects 3D information onto a 2D plane. Hence, radiograph analysis naturally requires physicians to relate the prior about 3D human anatomy to 2D…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Cheng Peng , Haofu Liao , Gina Wong , Jiebo Luo , Shaohua Kevin Zhou , Rama Chellappa

A sparse modeling approach is proposed for analyzing scanning tunneling microscopy topography data, which contains numerous peaks corresponding to surface atoms. The method, based on the relevance vector machine with $\mathrm{L}_1$…

Data Analysis, Statistics and Probability · Physics 2018-03-13 Masamichi J. Miyama , Koji Hukushima

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Small intestinal capsule endoscopy is the mainstream method for inspecting small intestinal lesions,but a single small intestinal capsule endoscopy will produce 60,000 - 120,000 images, the majority of which are similar and have no…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Rui Nie , Huan Yang , Hejuan Peng , Wenbin Luo , Weiya Fan , Jie Zhang , Jing Liao , Fang Huang , Yufeng Xiao

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…