Related papers: Monte Carlo simulation of SARS-CoV-2 radiation-ind…
Since the epidemic began in November 2019, no viable medicine against SARS-CoV-2 has been discovered. The typical medication discovery strategy requires several years of rigorous research and development as well as a significant financial…
Drug repurposing can accelerate the identification of effective compounds for clinical use against SARS-CoV-2, with the advantage of pre-existing clinical safety data and an established supply chain. RNA viruses such as SARS-CoV-2…
The SARS-CoV-2 RNA pseudoknot is a promising target for antiviral intervention, as it regulates the efficiency of $-$1 programmed ribosomal frameshifting ($-$1 PRF), a mechanism that is essential for viral protein synthesis. The pseudoknot…
We study the acceleration of heavy nuclei at SNR shocks taking into account the process of ionization. In the interstellar medium atoms heavier then hydrogen which start the diffusive shock acceleration (DSA) are never fully ionized at the…
Sequential Monte Carlo (SMC) methods are widely used to draw samples from intractable target distributions. Particle degeneracy can hinder the use of SMC when the target distribution is highly constrained or multimodal. As a motivating…
Despite the availability of effective vaccines, the persistence of SARS-CoV-2 suggests that co-circulation with other pathogens and resulting multi-epidemics may become increasingly frequent. To better forecast and control the risk of such…
Comptonization is the process in which photon spectrum changes due to multiple Compton scatterings in the electronic plasma. It plays an important role in the spectral formation of astrophysical X-ray and gamma-ray sources. There are…
Published survival data for V79 cells irradiated by monoenergetic protons, helium-3, carbon, and oxygen ions and for CHO cells irradiated by carbon ions have been analyzed using the probabilistic two-stage model of cell inactivation. Three…
The Distributed Electronic Cosmic-ray Observatory (DECO) is a cell phone app that uses a cell phone camera image sensor to detect cosmic-ray particles and particles from radioactive decay. Images recorded by DECO are classified by a…
Monte Carlo simulations are performed to study structure and dynamics of a protein CoVE in random media generated by a random distribution of barriers at concentration c with a coarse-grained model in its native (low temperature) and…
To overcome the problem of inefficient computing time and unreliable results in MCNP5 calculation, a two-step method is adopted to calculate the energy deposition of prompt gamma-rays in detectors for depleted uranium spherical shells under…
We introduce a computationally efficient and general approach for utilizing multiple, possibly interval-censored, data streams to study complex biomedical endpoints using multistate semi-Markov models. Our motivating application is the…
A new coronavirus identified as SARS-CoV-2 virus has brought the world to a state of crisis, causing a major pandemic, claiming more than 433,000 lives and instigating major financial damage to the global economy. Despite current efforts,…
Airborne particles are the medium for SARS-CoV-2 to invade the human body. Light also reflects through suspended particles in the air, allowing people to see a colorful world. Impressionism is the most prominent art school that explores the…
We apply the Monte Carlo Wave Packet (MCWP) approach to investigate the kinetic energy release (KER) spectra of the protons following double ionization in H$_{2}$ when interacting with laser pulses with central wavelengths ranging from the…
We develop a kinetic reaction model for cells having irradiated DNA molecules due to ionizing radiation exposure. Our theory simultaneously accounts for the time-dependent reactions of the DNA damage, the DNA mutation, the DNA repair, and…
The measurement of the beta asymmetry parameter in nuclear beta decay is a potentially very sensitive tool to search for non V-A components in the charge-changing weak interaction. To reach the required precision (percent level) all effects…
COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in…
Radiation mediated shocks (RMS) play a key role in shaping the early emission observed in many transients. In most cases, e.g., shock breakout in supernovae, llGRBs and neutron star mergers, the upstream plasma is devoid of radiation, and…
The world has witnessed unprecedented human and economic loss from the COVID-19 disease, caused by the novel coronavirus SARS-CoV-2. Extensive research is being conducted across the globe to identify therapeutic agents against the…