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Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

A three-dimensional Monte Carlo code for modelling radiation transport in Type Ia supernovae is described. In addition to tracking Monte Carlo quanta to follow the emission, scattering and deposition of radiative energy, a scheme involving…

Astrophysics · Physics 2008-11-26 S. A. Sim

A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dynamics to provide…

Populations and Evolution · Quantitative Biology 2025-11-25 Andrea Bondesan , Antonio Piralla , Elena Ballante , Antonino Maria Guglielmo Pitrolo , Silvia Figini , Fausto Baldanti , Mattia Zanella

While facial coverings over the nose and mouth reduce the spread of the virus SARS-CoV-2 by filtration, masks capable of viral inactivation by heating could provide a complementary method to limit viral transmission. In this work, we…

The development of highly sensitive and rapid biosensing tools targeted to the highly contagious virus SARS-CoV-2 is critical to tackling the COVID-19 pandemic. Quantum sensors can play an important role, thanks to their superior…

Quantum Physics · Physics 2022-01-25 Changhao Li , Rouhollah Soleyman , Mohammad Kohandel , Paola Cappellaro

The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December…

Genomics · Quantitative Biology 2020-03-25 Changchuan Yin

We propose a novel numerical method able to determine efficiently and effectively the relationship of complementarity between portions of proteins surfaces. This innovative and general procedure, based on the representation of the molecular…

Comprehensive studies with the MARS15(2016) Monte-Carlo code are described on evaluation of prompt and residual radiation levels induced by nominal and accidental beam losses in the 5-MW, 2-GeV European Spallation Source (ESS) Linac. These…

Accelerator Physics · Physics 2017-05-08 N. V. Mokhov , Yu. I. Eidelman , I. L. Rakhno , L. Tchelidze , I. S. Tropin

The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body,…

Biological Physics · Physics 2021-02-11 Yue-wen Yin , Yan-jing Sheng , Min Wang , Song-di Ni , Hong-ming Ding , Yu-qiang Ma

Recent developments have renewed the demand for solar cells with increased tolerance to radiation damage. To investigate the specific irradiation damage of 1 MeV electron irradiation in GaInAsP lattice matched to InP for varying In and P…

Applied Physics · Physics 2020-04-09 R. Lang , J. Schön , J. Lefèvre , B. Boizot , F. Dimroth , D. Lackner

A physical model based on a Monte-Carlo approach is proposed to calculate the ionization dynam- ics of warm dense matters (WDM) within particle-in-cell simulations, and where the impact (col- lision) ionization (CI), electron-ion…

Plasma Physics · Physics 2017-03-08 D. Wu , X. T. He , W. Yu , S. Fritzsche

Modelling of massive stars and supernovae (SNe) plays a crucial role in understanding galaxies. From this modelling we can derive fundamental constraints on stellar evolution, mass-loss processes, mixing, and the products of…

Atomic Physics · Physics 2016-09-07 N. B. Tyndall , C. A. Ramsbottom , C. P. Ballance , A. Hibbert

B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to…

Quantitative Methods · Quantitative Biology 2021-03-23 Bhargab Ghoshal , Biraja Ghoshal , Stephen Swift , Allan Tucker

The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…

Machine Learning · Computer Science 2021-10-20 Zahra Tayebi , Sarwan Ali , Murray Patterson

A molecule of dimension 125nm has caused around 479 Million human infections (80M for the USA) & 6.1 Million human deaths (977,000 for the USA) worldwide and slashed the global economy by US$ 8.5 Trillion over two years. The only other…

Biomolecules · Quantitative Biology 2022-06-29 Jatin Kashyap , Dibakar Datta

The ion production in an ECRIS is modelled using a particle-in-cell Monte-Carlo collision code in a three-dimensional geometry. Only the heavy particles (ions and atoms) are tracked, with the electron density determined from the requirement…

Atomic Physics · Physics 2009-07-29 V. Mironov , J. P. M. Beijers

Oncolytic virotherapy - the use of viruses that specifically kill tumor cells - is an innovative and highly promising route for treating cancer. However, its therapeutic outcomes are mainly impaired by the host immune response to the viral…

Tissues and Organs · Quantitative Biology 2015-06-15 Leticia R Paiva , Hallan S Silva , Silvio C Ferreira , Marcelo L Martins

SARS-CoV-2 has characteristics of wide contagion and quick propagation velocity. To analyse the visual information of it, we build a SARS-CoV-2 Microscopic Image Dataset (SC2-MID) with 48 electron microscopic images and also prepare their…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Chen Li , Jiawei Zhang , Frank Kulwa , Shouliang Qi , Ziyu Qi

Development of new drugs is an expensive and time-consuming process. Due to the world-wide SARS-CoV-2 outbreak, it is essential that new drugs for SARS-CoV-2 are developed as soon as possible. Drug repurposing techniques can reduce the time…

Machine Learning · Computer Science 2022-01-19 Shrimon Mukherjee , Madhusudan Ghosh , Partha Basuchowdhuri

The outbreak of COVID-19 caused millions of deaths worldwide, and the number of total infections is still rising. It is necessary to identify some potentially effective drugs that can be used to prevent the development of severe symptoms or…

Molecular Networks · Quantitative Biology 2022-09-07 Fan Hu , Jiaxin Jiang , Peng Yin