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Related papers: Monte Carlo simulation of SARS-CoV-2 radiation-ind…

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Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much of…

Genomics · Quantitative Biology 2020-04-30 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Purpose: To present a closed formalism calculating charged particle radiation damage induced in DNA. The formalism is valid for all types of charged particles and due to its closed nature is suited to provide fast conversion of dose to…

Medical Physics · Physics 2016-04-13 Frank Van den Heuvel

Due to its high lethality amongst the elderly, the safety of nursing homes has been of central importance during the COVID-19 pandemic. With test procedures becoming available at scale, such as antigen or RT-LAMP tests, and increasing…

Model of biological effects of ionizing particles, especially of protons and other ions, is proposed. The model is based on distinguishing the single-particle and collective effects of the underlying radiobiological mechanism. The…

Biological Physics · Physics 2016-08-16 Pavel Kundrát , Miloš Lokajíček , Hana Hromčíková

The objective of this paper is to provide a mathematical model to construct a barrier that may be useful to prevent the penetration of different viruses (Eg. SARS-COV-2) as well as charged aerosols through the concept of electrostatic…

Medical Physics · Physics 2020-06-19 Kausik Rakshit , Sudip Chatterjee , Durjoy Bandyopadhyay , Somsekhar Sarkar

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

Medical Physics · Physics 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

Quantitative Methods · Quantitative Biology 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

The present work introduces a rigorous stochastic model, named Generalized Stochastic Microdosimetric Model (GSM2), to describe biological damage induced by ionizing radiation. Starting from microdosimetric spectra of energy deposition in…

Biological Physics · Physics 2021-01-27 F. Cordoni , M. Missiaggia , A. Attili , S. M. Welford , E. Scifoni , C. La Tessa

The current pandemic of SARS-CoV-2 has caused extensive damage to society. The characterization of SARS-CoV-2 profiles has been addressed by researchers globally with the aim of resolving this disruptive crisis. This investigation process…

Molecular Networks · Quantitative Biology 2020-08-24 Yoshihisa Tanaka , Kako Higashihara , Mai Adachi Nakazawa , Fumiyoshi Yamashita , Yoshinori Tamada , Yasushi Okuno

Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. Here, based on the assumption of a weak and delayed response…

Populations and Evolution · Quantitative Biology 2021-01-13 Zhengqing Zhou , Zhiheng Zhao , Shuyu Shi , Jianghua Wu , Dianjie Li , Jianwei Li , Jingpeng Zhang , Ke Gui , Yu Zhang , Heng Mei , Yu Hu , Qi Ouyang , Fangting Li

Objective: This work presents a data-driven importance sampling-based variance reduction (VR) scheme inspired by active learning. The method is applied to the estimation of an optimal impact-parameter distribution in the calculation of…

Medical Physics · Physics 2025-11-04 Leo Thomas , Miriam Schwarze , Hans Rabus

The COVID-19 pandemic has stimulated the scientific world to intensify virus-related studies, aimed at the development of quick and safe ways of detecting viruses in human body, studying the virus-antibody and virus-cell interactions, and…

Monte Carlo techniques based on indivisible energy packets are described for computing light curves and spectra for 3-D supernovae. The radiative transfer is time-dependent and includes all effects of O(v/c). Monte Carlo quantization is…

Astrophysics · Physics 2009-11-10 L. B. Lucy

The deadly coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gone out of control globally. Despite much effort by scientists, medical experts, and society in general, the…

Biomolecules · Quantitative Biology 2021-02-02 Kaifu Gao , Rui Wang , Jiahui Chen , Limei Cheng , Jaclyn Frishcosy , Yuta Huzumi , Yuchi Qiu , Tom Schluckbier , Guo-Wei Wei

Structure-based Deep Fusion models were recently shown to outperform several physics- and machine learning-based protein-ligand binding affinity prediction methods. As part of a multi-institutional COVID-19 pandemic response, over 500…

We estimate the reduction in transmission of SARS-CoV-2 achievable by surveillance testing of a susceptible population at different frequencies, comparing the cases of both the original Wuhan strain and the Delta variant. We estimate the…

Physics and Society · Physics 2021-10-04 Ahmed Elbanna , Nigel Goldenfeld

A Monte Carlo model has been developed to study the degradation of <1000 eV electrons in an atmosphere of CO2, which is one of the most abundant species in Mars' and Venus' atmospheres. The e-CO2 cross sections are presented in an assembled…

Earth and Planetary Astrophysics · Physics 2010-11-22 Anil Bhardwaj , Sonal Kumar Jain

The spike protein (SP) of SARS-CoV-2 is the major molecular target for making diagnostic tests, vaccines, and therapeutic development. We used a combination of transmission electron microscopy (TEM) and surface enhanced Raman microscopy…

Biological Physics · Physics 2025-01-30 Monika Ghalawat , Virendra Kumar Meena , Sharda Prasad , Pankaj Poddar , Atanu Basu

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global medical systems and economies, and rules our daily living life. Controlling the outbreak of SARS-CoV-2 has become one of the most important…

Medical Physics · Physics 2020-10-09 Jing Zhong , Enja Laureen Roesch , Thilo Viereck , Meinhard Schilling , Frank Ludwig

Proteins can exhibit dynamic structural flexibility as they carry out their functions, especially in binding regions that interact with other molecules. For the key SARS-CoV-2 spike protein that facilitates COVID-19 infection, studies have…

Applications · Statistics 2022-02-08 Samuel W. K. Wong