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Single-cell RNA sequencing (scRNA-seq) technology has profiled hundreds of millions of human cells across organs, diseases, development and perturbations to date. However, the high-dimensional sparsity, batch effect noise, category…
Many approaches to transform classification problems from non-linear to linear by feature transformation have been recently presented in the literature. These notably include sparse coding methods and deep neural networks. However, many of…
In many modern machine learning applications, the outcome is expensive or time-consuming to collect while the predictor information is easy to obtain. Semi-supervised learning (SSL) aims at utilizing large amounts of `unlabeled' data along…
Single-cell RNA-seq data are challenging because of the sparseness of the read counts, the tiny expression of many relevant genes, and the variability in the efficiency of RNA extraction for different cells. We consider a simple…
Single-cell RNA sequencing provides tremendous insights to understand biological systems. However, the noise from dropout can corrupt the downstream biological analysis. Hence, it is desirable to impute the dropouts accurately. In this…
In this paper, we present a deep neural network (DNN) training approach called the "DeepMimic" training method. Enormous amounts of data are available nowadays for training usage. Yet, only a tiny portion of these data is manually labeled,…
Semi-supervised multi-organ medical image segmentation aids physicians in improving disease diagnosis and treatment planning and reduces the time and effort required for organ annotation.Existing state-of-the-art methods train the labeled…
The popular methods for semi-supervised semantic segmentation mostly adopt a unitary network model using convolutional neural networks (CNNs) and enforce consistency of the model's predictions over perturbations applied to the inputs or…
Semi-Supervised Learning (SSL) is a framework that utilizes both labeled and unlabeled data to enhance model performance. Conventional SSL methods operate under the assumption that labeled and unlabeled data share the same label space.…
Semi-supervised learning (SSL) aims to train a machine learning model using both labelled and unlabelled data. While the unlabelled data have been used in various ways to improve the prediction accuracy, the reason why unlabelled data could…
Recent studies have shown that the benefits provided by self-supervised pre-training and self-training (pseudo-labeling) are complementary. Semi-supervised fine-tuning strategies under the pre-training framework, however, remain…
We have gained access to vast amounts of multi-omics data thanks to Next Generation Sequencing. However, it is challenging to analyse this data due to its high dimensionality and much of it not being annotated. Lack of annotated data is a…
Classes, as fundamental elements of Computer Vision, have been extensively studied within incremental learning frameworks. In contrast, tokens, which play essential roles in many research fields, exhibit similar characteristics of growth,…
Long non-coding RNAs (lncRNAs) are important regulators to modulate gene expression and cell proliferation in the developing human brain. Previous methods mainly use bulk lncRNA and mRNA expression data to study lncRNA regulation. However,…
Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…
Deep learning based image segmentation has achieved the state-of-the-art performance in many medical applications such as lesion quantification, organ detection, etc. However, most of the methods rely on supervised learning, which require a…
Semi-supervised 3D medical image segmentation aims to achieve accurate segmentation using few labelled data and numerous unlabelled data. The main challenge in the design of semi-supervised learning methods consists in the effective use of…
In this paper, we propose a semi-supervised deep learning method for detecting the specific types of reads that impede the de novo genome assembly process. Instead of dealing directly with sequenced reads, we analyze their coverage graphs…
Single-cell RNA sequencing technologies have revolutionized our understanding of cellular heterogeneity, yet computational methods often struggle to balance performance with biological interpretability. Embedded topic models have been…
This paper studies semi-supervised graph classification, a crucial task with a wide range of applications in social network analysis and bioinformatics. Recent works typically adopt graph neural networks to learn graph-level representations…