Related papers: A sharp-front moving boundary model for malignant …
In this paper, we study a cancer invasion model both theoretically and numerically. The model is a nonstationary, nonlinear system of three coupled partial differential equations modeling the motion of cancer cells, degradation of the…
We investigate a model of solid propellant combustion involving surface pyrolysis coupled to finite activation energy gas phase combustion. Existence and uniqueness of a travelling wave solution are established by extending dynamical system…
We study two systems of reaction diffusion equations with monostable or bistable type of nonlinearity and with free boundaries. These systems are used as multi-species competitive model. For two-species models, we prove the existence of a…
We introduce a two-dimensional Hele-Shaw type free boundary model for motility of eukaryotic cells on substrates. The key ingredients of this model are the Darcy law for overdamped motion of the cytoskeleton gel (active gel) coupled with…
Travelling wave solutions of reaction-diffusion equations are widely used to model the spatial spread of populations and other phenomena in biology and physics. In this article, we reinterpret the classical variational principle approach…
Phase-field models have recently had great success in describing the dynamic morphologies and motility of eukaryotic cells. In this work we investigate the minimal phase-field model introduced in [Berlyand, Potomkin, Rybalko (2017)].…
We are interested in the invasion phase for stochastic processes with interactions when a single mutant with positive fitness arrives in a resident population at equilibrium. By a now classic approach, the first stage of the invasion is…
We consider a time-continuous Markov branching process of proliferating cells with a countable collection of types. Among-type transitions are inspired by the Tug-of-War process introduced in McFarland et al. as a mathematical model for…
One of the most crucial and lethal characteristics of solid tumors is represented by the increased ability of cancer cells to migrate and invade other organs during the so-called metastatic spread. This is allowed thanks to the production…
An analysis of traveling wave solutions of partial differential equation (PDE) systems with cross-diffusion is presented. The systems under study fall in a general class of the classical Keller-Segel models to describe chemotaxis. The…
Interstitial fluid flow is a feature of many solid tumours. In vitro Experiments have shown that such fluid flow can direct tumour cell movement upstream or downstream depending on the balance between the competing mechanisms of tensotaxis…
Reaction-diffusion waves in multiple spatial dimensions advance at a rate that strongly depends on the curvature of the wave fronts. These waves have important applications in many physical, ecological, and biological systems. In this work,…
The spatio-temporal aspects of the transition to turbulence are considered in the case of a boundary layer flow developing above a flat plate exposed to free-stream turbulence. Combining results on the receptivity to free-stream turbulence…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…
We obtain exact travelling wave solutions for three families of stochastic one-dimensional nonequilibrium lattice models with open boundaries. These solutions describe the diffusive motion and microscopic structure of (i) of shocks in the…
Analysis of the speed of propagation in parabolic operators is frequently carried out considering the minimal speed at which its traveling waves move. This value depends on the solution concept being considered. We analyze an extensive…
Cancer cell invasion is recognised as one of the hallmarks of cancer and involves several inner-related multiscale processes that ultimately contribute to its spread into the surrounding tissue. In order to gain a deeper understanding of…
In this paper we study a nonlinear free boundary problem on the radial growth of a two-layer solid tumor with a quiescent core. The tumor surface and its inner interface separating the proliferating cells and the quiescent cells are both…
The emergent dynamics in phase-separated mixtures of isometric active and passive Brownian particles is studied numerically in two dimensions. A novel steady-state of well-defined traveling fronts is observed, where the interface between…
We perform the analysis of a hyperbolic model which is the analog of the Fisher-KPP equation. This model accounts for particles that move at maximal speed $\epsilon^{-1}$ ($\epsilon\textgreater{}0$), and proliferate according to a reaction…