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We prove the existence of a family of travelling wave solutions in a variant of the $\textit{Zeldovich-Frank-Kamenetskii (ZFK) equation}$, a reaction-diffusion equation which models the propagation of planar laminar premixed flames in…
We consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. The model is derived by taking the incompressible limit of porous medium type equations, and the boundary instability of this model was recently studied…
We study a family of reaction-diffusion equations that present a doubly nonlinear character given by a combination of the $p$-Laplacian and the porous medium operators. We consider the so-called slow diffusion regime, corresponding to a…
Self-activation coupled to a transport mechanism results in traveling waves that describe polymerization reactions, forest fires, tumor growth, and even the spread of epidemics. Diffusion is a simple and commonly used model of particle…
We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…
A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…
This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…
The Stefan problem is a classical free-boundary problem that models phase-change processes and poses computational challenges due to its moving interface and nonlinear temperature-phase coupling. In this work, we develop a physics-informed…
We investigate a recently proposed cross-diffusion system modelling the growth of gliobastoma taking into account size exclusion both in the migration and proliferation process. In addition to degenerate nonlinear cross-diffusion the model…
We propose a two-component reaction-transport model for the migration-proliferation dichotomy in the spreading of tumor cells. By using a continuous time random walk (CTRW) we formulate a system of the balance equations for the cancer cells…
Tumour invasion is an essential stage of cancer progression. Its main drivers are diffusion and taxis, a directed movement along the gradient of a stimulus. Here we review models with flux limited diffusion and/or taxis which have…
Invasiveness, one of the hallmarks of tumor progression, represents the tumor's ability to expand into the host tissue by means of several complex biochemical and biomechanical processes. Since certain aspects of the problem present a…
We prove the existence and uniqueness of a traveling front and of its speed for the homogeneous heat equation in the half-plane with a Neumann boundary reaction term of non-balanced bistable type or of combustion type. We also establish the…
The proliferation and migration dichotomy of the tumor cell invasion is examined within a two-component continuous time random walk (CTRW) model. The balance equations for the cancer cells of two phenotypes with random switching between…
Cellular populations such as avascular tumors and microbial biofilms may "invade" or grow into surrounding populations. The invading population is often comprised of a heterogeneous mixture of cells with varying growth rates. The population…
Predicting evolution of expanding populations is critical to control biological threats such as invasive species and cancer metastasis. Expansion is primarily driven by reproduction and dispersal, but nature abounds with examples of…
We study the invasion of an unstable state by a propagating front in a peculiar but generic situation where the invasion process exhibits a remnant instability. Here, remnant instability refers to the fact that the spatially constant…
The understanding of cross-field transport is crucial in order to optimize the properties of magnetic confinement in modern fusion devices. In this work, a two-dimensional, simplified model is used to study the turbulent dynamics in the…
We consider a reaction-diffusion system of densities of two types of particles, introduced by Edouard Hannezo et al. in the context of branching morphogenesis. It is a simple model for a growth process: active, branching particles form the…
Morphological instabilities of growing tissues that impinge on passive materials are typical of invasive cancers. To explain these instabilities in experiments on breast epithelial spheroids in an extracellular matrix, we develop a…