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Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

Methodology · Statistics 2020-08-26 Arjun Kodialam

The issue of COVID-19, increasing with a massive mortality rate. This led to the WHO declaring it as a pandemic. In this situation, it is crucial to perform efficient and fast diagnosis. The reverse transcript polymerase chain reaction…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Lalith Bharadwaj B , Rohit Boddeda , Sai Vardhan K , Madhu G

The COVID-19 pandemic poses challenges for continuing economic activity while reducing health risks. While these challenges can be mitigated through testing, testing budget is often limited. Here we study how institutions, such as nursing…

Physics and Society · Physics 2021-01-05 Janni Yuval , Mor Nitzan , Neta Ravid Tannenbaum , Boaz Barak

We estimate the reduction in transmission of SARS-CoV-2 achievable by surveillance testing of a susceptible population at different frequencies, comparing the cases of both the original Wuhan strain and the Delta variant. We estimate the…

Physics and Society · Physics 2021-10-04 Ahmed Elbanna , Nigel Goldenfeld

The recent COVID-19 pandemic underscores the significance of early-stage non-pharmacological intervention strategies. The widespread use of masks and the systematic implementation of contact tracing strategies provide a potentially equally…

Populations and Evolution · Quantitative Biology 2024-09-02 A. P. Muntoni , F. Mazza , A. Braunstein , G. Catania , L. Dall'Asta

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

Testing individuals for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen causing the coronavirus disease 2019 (COVID-19), is crucial for curtailing transmission chains. Moreover, rapidly testing…

Applications · Statistics 2021-03-08 Yair Daon , Amit Huppert , Uri Obolski

We propose a mathematical model with five compartments for the SARS-CoV-2 transmission: susceptible $S$, undetected infected asymptomatic $A$, undetected infected symptomatic $I$, confirmed positive and isolated $L$, and recovered $ R$, for…

Optimization and Control · Mathematics 2020-09-29 Gabriela Marinoschi

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

Major advances in public health have resulted from disease prevention. However, prevention of a new infectious disease by vaccination or pharmaceuticals is made difficult by the slow process of vaccine and drug development. We propose an…

Populations and Evolution · Quantitative Biology 2021-04-15 Jussi Taipale , Ioannis Kontoyiannis , Sten Linnarsson

There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

Applications · Statistics 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

The experience of Singapur and South Korea makes it clear that under certain circumstances massive testing is an effective way for containing the advance of the COVID-19. In this paper, we propose a modified SEIR model which takes into…

Applications · Statistics 2020-12-24 José Luis Sainz-Pardo , José Valero

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

The outbreak of the global COVID-19 pandemic results in unprecedented demand for fast and efficient testing of large numbers of patients for the presence of SARS-CoV-2 coronavirus. Beside technical improvements of the cost and speed of…

Methodology · Statistics 2020-12-16 Andrzej Jaszkiewicz

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

Using recent data from voluntary mass testing, I provide credible bounds on prevalence of SARS-CoV-2 for Austrian counties in early December 2020. When estimating prevalence, a natural missing data problem arises: no test results are…

General Economics · Economics 2020-12-23 Gabriel Ziegler

Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…

Social and Information Networks · Computer Science 2020-11-16 Gianluca Manzo , Arnout van de Rijt

In February 2020 the first human infection with SARS-CoV-2 was reported in Germany. Since then the local public health offices have been responsible to monitor and react to the dynamics of the pandemic. One of their major tasks is to…

Applications · Statistics 2021-07-02 Sonja Jäckle , Elias Röger , Volker Dicken , Benjamin Geisler , Jakob Schumacher , Max Westphal

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

Quantitative Methods · Quantitative Biology 2022-08-31 Amit Solomon , Alejandro Cohen , Nir Shlezinger , Yonina C. Eldar , Muriel Médard

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli