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We construct an SIR-type model for COVID-19, incorporating as a parameter the susceptible individuals' cautiousness level. We determine the model's basic reproduction number, study the stability of the equilibria analytically, and perform a…

Dynamical Systems · Mathematics 2022-04-06 Benny Yong , Livia Owen , Jonathan Hoseana

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

Physics and Society · Physics 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

In the context of a pandemic like COVID-19, and until most people are vaccinated, proactive testing and interventions have been proved to be the only means to contain the disease spread. Recent academic work has offered significant evidence…

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

Optimization and Control · Mathematics 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

We are currently facing a highly critical case of a world-wide pandemic. The novel coronavirus (SARS-CoV-2, a.k.a. COVID-19) has proved to be extremely contagious and the original outbreak from Asia has now spread to all continents. This…

Physics and Society · Physics 2020-06-26 Priyanka , Vicky Verma

Containment measures implemented by some countries to suppress the spread of COVID-19 have resulted in a slowdown of the epidemic characterized by time series of daily infections plateauing over extended periods of time. We prove that such…

Physics and Society · Physics 2020-11-17 Filippo Radicchi , Ginestra Bianconi

A model of reactive social distancing in epidemics is proposed, in which the infection rate changes with the number infected. The final-size equation for the total number that the epidemic will infect can be derived analytically, as can the…

Populations and Evolution · Quantitative Biology 2020-03-19 Rose Baker

This paper considers a stochastic SIR (susceptible$\to$infective$\to$removed) epidemic model in which individuals may make infectious contacts in two ways, both within `households' (which for ease of exposition are assumed to have equal…

Probability · Mathematics 2015-03-13 Frank Ball , David Sirl , Pieter Trapman

In this work, the SIR epidemiological model is reformulated so to highlight the important {\em effective reproduction number}, as well as to account for the {\em generation time}, inverse of the {\em incidence rate}, and the {\em infectious…

Populations and Evolution · Quantitative Biology 2021-07-27 Ignazio Lazzizzera

Testing for infection with SARS-CoV-2 is an important intervention in reducing onwards transmission of COVID-19, particularly when combined with the isolation and contact-tracing of positive cases. Many countries with the capacity to do so…

Populations and Evolution · Quantitative Biology 2022-07-19 Miguel E. P. Silva , Martyn Fyles , Li Pi , Jasmina Panovska-Griffiths , Caroline Jay , Thomas House , Elizabeth Fearon

Motivated with various responses of world governments to COVID-19, here we develop a toy model of the dependence epidemics spreading on the availability of tests for disease. Our model, that we call SUDR+K, is based on usual SIR model, but…

Populations and Evolution · Quantitative Biology 2020-12-01 Vinko Zlatić , Irena Barjašić , Andrea Kadović , Hrvoje Štefančić , Andrea Gabrielli

We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…

Populations and Evolution · Quantitative Biology 2021-02-22 Sara Pasquali , Antonio Pievatolo , Antonella Bodini , Fabrizio Ruggeri

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Tarun Jain , Bijendra Nath Jain

A stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a social network is analysed. The underlying social network is described by an Erd\H{o}s-R\'{e}nyi random graph but, during the course of the epidemic,…

Probability · Mathematics 2020-08-17 Frank Ball , Tom Britton

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

Physics and Society · Physics 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

We study a dynamic infection spread model, inspired by the discrete time SIR model, where infections are spread via non-isolated infected individuals. While infection keeps spreading over time, a limited capacity testing is performed at…

Methodology · Statistics 2022-01-25 Batuhan Arasli , Sennur Ulukus

Given maximal social distancing duration and intensity, how can one minimize the epidemic final size, or equivalently the total number of individuals infected during the outbreak? A complete answer to this question is provided and…

Optimization and Control · Mathematics 2020-10-01 Pierre-Alexandre Bliman , Michel Duprez