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Infection spread among individuals is modelled with a continuous time Markov chain, in which subject interactions depend on their distance in space. The well known SIR model and non local variants of the latter are then obtained as large…

Probability · Mathematics 2023-09-27 Franco Flandoli , Francesco Grotto , Andrea Papini , Cristiano Ricci

We consider a simple deterministic model which describes an asymmetric competition between an immune system with a specific and powerful response, and a virus with a broad toxicity and fast mutations. Interest in this model relies on the…

Quantitative Methods · Quantitative Biology 2011-01-17 Thierry Gobron , Mario Santoro , Livio Triolo

The purpose of this paper is to analyze the mechanism for the interplay of deterministic and stochastic models for contagious diseases. Deterministic models for contagious diseases are prone to predict global stability. Small natural birth…

Populations and Evolution · Quantitative Biology 2022-06-17 Torsten Lindström

Background. Several studies have used phylogenetics to investigate Human Immunodeficiency Virus (HIV) transmission among Men who have Sex with Men (MSMs) in Montreal, Quebec, Canada, revealing many transmission clusters. The Quebec HIV…

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

Populations and Evolution · Quantitative Biology 2021-12-07 Nicholas Landry

In dynamic models of infectious disease transmission, typically various mixing patterns are imposed on the so-called Who-Acquires-Infection-From-Whom matrix (WAIFW). These imposed mixing patterns are based on prior knowledge of age-related…

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

We investigate SIR models with vital dynamics, reinfection, and randomness at the transmission coefficient and recruitment rate. Initially, we conduct an extensive analysis of the autonomous scenario, covering aspects such as local and…

Dynamical Systems · Mathematics 2024-04-22 Javier López-de-la-Cruz , Alexandre N. Oliveira-Sousa

This paper considers a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and varying total population. The interaction of the susceptible and infected people is describe by the…

Analysis of PDEs · Mathematics 2024-12-13 Rui Peng , Rachidi B. Salako , Yixiang Wu

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

We study a discrete Susceptible-Infected-Recovered (SIR) model for the spread of infectious disease on a homogeneous tree and the limit behavior of the model in the case when the tree vertex degree tends to infinity. We obtain the…

Probability · Mathematics 2022-07-08 Alexander Gairat , Vadim Shcherbakov

Key populations at high risk of HIV infection are critical for understanding and monitoring HIV epidemics, but global estimation is hampered by sparse, uneven data. We analyze data from 199 countries for female sex workers (FSW), men who…

Applications · Statistics 2025-09-16 Jiahao Zhang , Keith Sabin , Le Bao

To better describe the spread of a disease, we extend a discrete time stochastic SIR-type epidemic model of Tuckwell and Williams. We assume the dependence on time of the number of daily encounters and include a parameter to represent a…

Populations and Evolution · Quantitative Biology 2022-09-30 Mireia Besalú , Giulia Binotto

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

We apply the cavity master equation (CME) approach to epidemics models. We explore mostly the susceptible-infectious-susceptible (SIS) model, which can be readily treated with the CME as a two-state. We show that this approach is more…

Physics and Society · Physics 2021-03-02 Ernesto Ortega , David Machado , Alejandro Lage-Castellanos

Pandemics can cause immense disruption and damage to communities and societies. Thus far, modeling of pandemics has focused on either large-scale difference equation models like the SIR and the SEIR models, or detailed micro-level…

Multiagent Systems · Computer Science 2010-07-27 Teruhiko Yoneyama , Sanmay Das , Mukkai Krishnamoorthy

Contact patterns in populations fundamentally influence the spread of infectious diseases. Current mathematical methods for epidemiological forecasting on networks largely assume that contacts between individuals are fixed, at least for the…

Populations and Evolution · Quantitative Biology 2007-05-23 Erik Volz , Lauren Ancel Meyers

In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape from multiple CTL responses. Under this model, we describe two…

Populations and Evolution · Quantitative Biology 2012-08-16 Sivan Leviyang

We perform a bifurcation analysis on an SIR model involving two pathogens that influences each other. Partial cross-immunity is assumed and coinfection is thought to be less transmittable then each of the diseases alone. The susceptible…

Dynamical Systems · Mathematics 2022-09-09 J. Andersson , V. Kozlov , V. G. Tkachev , U. Wennergren

In this paper we elaborate on homogeneous and heterogeneous SIR-type epidemiological models. We find an unexpected correspondence between the epidemic trajectory of a transmissible disease in a homogeneous SIR-type model and radial null…

Populations and Evolution · Quantitative Biology 2023-08-04 Silke Klemm , Lucrezia Ravera