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A novel approach to expedite design optimization of nonlinear beam dynamics in storage rings is proposed and demonstrated in this study. At each iteration, a neural network surrogate model is used to suggest new trial solutions in a…
With the explosive growth of mobile data, the demand of high-speed railway (HSR) passengers for broadband wireless access services urgently needs the support of ultra-highspeed scenario broadband wireless communication. Millimeterwave…
In this study, we propose an analytic statistical mechanics approach to solve a fundamental problem in biological physics called protein design. Protein design is an inverse problem of protein structure prediction, and its solution is the…
RNA secondary structure prediction is widely used to understand RNA function. Recently, there has been a shift away from the classical minimum free energy (MFE) methods to partition function-based methods that account for folding ensembles…
Shor's algorithm is one of the most prominent quantum algorithms, yet finding efficient implementations remains an active research challenge. While many approaches focus on low-level modular arithmetic optimizations, a broader perspective…
Large Reasoning Models (LRMs) demonstrate strong performance on complex tasks but often suffer from excessive verbosity, known as "overthinking." Existing solutions via reinforcement learning (RL) typically penalize generated tokens to…
A promising direction towards improving the performance of wave energy converter (WEC) farms is to leverage a system-level integrated approach known as control co-design (CCD). A WEC farm CCD problem may entail decision variables associated…
RNA co-transcriptionality, where RNA is spliced or folded during transcription from DNA templates, offers promising potential for molecular programming. It enables programmable folding of nano-scale RNA structures and has recently been…
Spiking neural networks (SNNs) exhibit superior energy efficiency but suffer from limited performance. In this paper, we consider SNNs as ensembles of temporal subnetworks that share architectures and weights, and highlight a crucial issue…
Monotonicity is a simple yet significant qualitative characteristic. We consider the problem of segmenting an array in up to K segments. We want segments to be as monotonic as possible and to alternate signs. We propose a quality metric for…
Antibody therapeutics and vaccines are among our last resort to end the raging COVID-19 pandemic. They, however, are prone to over 5,000 mutations on the spike (S) protein uncovered by a Mutation Tracker based on over 200,000 genome…
Spiking neural networks (SNNs), a brain-inspired computing paradigm, are emerging for their inference performance, particularly in terms of energy efficiency and latency attributed to the plasticity in signal processing. To deploy SNNs in…
This paper studies a fundamental problem in convex optimization, which is to solve semidefinite programming (SDP) with high accuracy. This paper follows from the existing robust SDP-based interior point method analysis due to [Huang, Jiang,…
Memristive crossbars have become a popular means for realizing unsupervised and supervised learning techniques. In previous neuromorphic architectures with leaky integrate-and-fire neurons, the crossbar itself has been separated from the…
In this paper, we revisit the problem of finding the longest systematic-length $k$ for a linear minimum storage regenerating (MSR) code with optimal repair of only systematic part, for a given per-node storage capacity $l$ and an arbitrary…
Alignment of structural RNAs is an important problem with a wide range of applications. Since function is often determined by molecular structure, RNA alignment programs should take into account both sequence and base-pairing information…
The past decade has demonstrated increasing interests in using optimal control based methods within coherent quantum controllable systems. The versatility of such methods has been demonstrated with particular elegance within nuclear…
The optimal fault-tolerance achievable by any protocol has been characterized in a wide range of settings. For example, for state machine replication (SMR) protocols operating in the partially synchronous setting, it is possible to…
Consider a multiuser downlink beamforming optimization problem for the non-orthogonal multiple access (NOMA) transmission in a multiple-input single-output (MISO) system. The total transmission power minimization problem is formulated…
Distribution matching (DM) transforms independent and Bernoulli(1/2) distributed bits into a sequence of output symbols with a desired distribution. A fixed-to-fixed length, invertible DM architecture based on shell mapping is presented. It…