Related papers: Tau affects P53 function and cell fate during the …
The next-to-next-to-leading order perturbative QCD corrections to R_tau and the higher moments of the invariant mass distribution in the hadronic tau decays are considered. The renormalization scheme dependence of these corrections is…
Topology affects physical and biological properties of DNA and impacts fundamental cellular processes, such as gene expression, genome replication, chromosome structure and segregation. In all organisms DNA topology is carefully modulated…
The loss of neuronal cells in the central nervous system may happen in numerous neurodegenerative illnesses. Alzheimer's Disease (AD) is an intricate, irreversible, dynamic neurodegenerative sickness. It is the main source of age-related…
In this Note we study a mathematical model for the progression of Alzheimer's Disease in the human brain. The novelty of our approach consists in the representation of the brain as two superposed graphs where toxic proteins diffuse, the…
The neutrino interaction length scales with energy, and becomes comparable to Earth's diameter above 10's of TeV energies. Over terrestrial distances, the tau's short lifetime leads to an energetic regenerated tau neutrino flux, tau…
A class of nucleosome remodeling motors translocate nucleosomes, to which they are attached, toward the middle of DNA chain in the presence of ATP during in vitro experiments. Such a biological activity is likely based on a physical…
We investigate rare decays of tau leptons that occur via exchange of heavy on-shell neutrinos $N_j$ ($j=1,2$). These neutrinos can be either Dirac or Majorana, and are considered to be almost degenerate in mass. The decays can thus be…
We report on a theoretical study of point mutations effects on charge transfer properties in the DNA sequence of the tumor-suppressor p53 gene. On the basis of effective single-strand or double-strand tight-binding models which simulate…
When evolution algorithms are used to unfold the neutron energy spectrum, fitness function design is an important fundamental work for evaluating the quality of the solution, but it has not attracted much attention. In this work, we…
We systematically investigate the possible complex transition origin of electronic excitations of giant molecular systems by using the recently proposed QNTO analysis [J.-H. Li, J.-D. Chai, G. Y. Guo and M. Hayashi, Chem. Phys. Lett., 2011,…
The model for cAMP-dependent synaptic plasticity relates the characterization of a noradrenaline-stimulated adenylyl cyclase with DNA unzipping. Specific proteins condition cAMP insertion in specific sites of the DNA structure to direct…
Currently, many studies of Alzheimer's disease (AD) are investigating the neurobiological factors behind the acquisition of beta-amyloid (A), pathologic tau (T), and neurodegeneration ([N]) biomarkers from neuroimages. However, a…
Status of tau lepton decay Monte Carlo generator TAUOLA is reviewed. Recent efforts on development of new hadronic currents are presented. Multitude new channels for anomalous tau decay modes and parametrization based on defaults used by…
Mismatch repair is a critical step in DNA replication that occurs after base selection and proofreading, significantly increasing fidelity. However, the mechanism of mismatch recognition has not been established for any repair enzyme.…
We show that QCD Minkowski observables such as the $e^{+}e^{-}$ R-ratio and the hadronic tau decay $R_{\tau}$ are completely determined by the effective charge (EC) beta-function, $\rho(x)$, corresponding to the Euclidean QCD vacuum…
We characterize in details the aging properties of the ferroelectric phase of K Ta_{1-x} Nb_x O_3 (KTN), where both rejuvenation and (partial) memory are observed. In particular, we carefully examine the frequency dependence of several…
This paper proposes that eukaryotic cells, under severe genotoxic stress, can commit genoautotomy (genome 'self-injury') that involves cutting and releasing single-stranded DNA (ssDNA) fragments from double-stranded DNA and leaving ssDNA…
By use of complex network dynamics and graph-based machine learning, we identified critical determinants of lineage-specific plasticity across the single-cell transcriptomics of pediatric high-grade glioma (pHGGs) subtypes: IDHWT…
In tumoral cells, gene regulation mechanisms are severely altered, and these modifications in the regulations may be characteristic of different subtypes of cancer. However, these alterations do not necessarily induce differential…
Protein-DNA complexes with loops play a fundamental role in a wide variety of cellular processes, ranging from the regulation of DNA transcription to telomere maintenance. As ubiquitous as they are, their precise in vivo properties and…