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Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…

Optics · Physics 2020-07-15 Ivan Zorin , Rong Su , Bettina Heise , Bernhard Lendl , Markus Brandstetter

Quantitative phase imaging (QPI) is important in many applications such as microscopy and crystallography. To quantitatively reveal phase information, people could either employ interference to map phase distribution into intensity fringes,…

Optics · Physics 2020-11-11 Xianye Li , Yafei sun , Yikang He , Xun Li , Baoqing Sun

Speckle noise has long been an extensively studied problem in medical imaging. In recent years, there have been significant advances in leveraging deep learning methods for noise reduction. Nevertheless, adaptation of supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Deborah Pereg

We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with axial resolution of 5.9 $\mu$m at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT…

Single photon detectors are indispensable tools in optics, from fundamental measurements to quantum information processing. The ability of superconducting nanowire single photon detectors to detect single photons with unprecedented…

We demonstrate optical coherence tomography based on an SU(1,1) nonlinear interferometer with high-gain parametric down-conversion. For imaging and sensing applications, this scheme promises to outperform previous experiments working at low…

Quantum Physics · Physics 2020-08-31 Gerard J. Machado , Gaetano Frascella , Juan P. Torres , Maria V. Chekhova

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

A neural-network (NN)-based method for high-speed, high-definition dynamic optical coherence tomography (DOCT) using full-field swept-source optical coherence microscopy (FF-SS-OCM) is demonstrated. FF-SS-OCM provides high-definition OCT…

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Photon statistics of an optical field can be used for quantum optical sensing in low light level scenarios free of bulky optical components. However, photon-number-resolving detection to unravel the photon statistics is challenging. Here,…

Quantum Physics · Physics 2023-07-31 F. Bao , L. Bauer , A. E. Rubio Lopez , Z. Jacob

We demonstrate a different scheme to perform optical sectioning of a sample based on the concept of induced coherence [Zou et al., Phys. Rev. Lett. 67, 318 (1991)]. This can be viewed as a different type of optical coherence tomography…

Quantum Physics · Physics 2018-02-19 Adam Vallés , Gerard Jiménez , Luis José Salazar-Serrano , Juan P. Torres

The integrated optical circuit is a promising architecture for the realization of complex quantum optical states and information networks. One element that is required for many of these applications is a high-efficiency photon detector…

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

Optics · Physics 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

In this paper, we present a novel concept for a multi-channel swept source optical coherence tomography (OCT) system based on photonic integrated circuits (PICs). At the core of this concept is a low-loss polarization dependent path routing…

Recording of transient absorption microscopy images requires fast detection of minute optical density changes, which is typically achieved with high-repetition-rate laser sources and lock-in detection. Here, we present a highly flexible and…

Many optical measurement techniques, such as light scattering from wavelength-scale particles or detecting motion from a surface with an optical lever, encode information in a complex radiation pattern. Extracting all available information…

Quantum Physics · Physics 2025-12-22 Youssef Tawfik , Shan Hao , Thomas P. Purdy

Coherence-domain imaging systems can be operated in a single-photon counting mode, offering low detector noise; this in turn leads to increased sensitivity for weak light sources and weakly reflecting samples. We have demonstrated that…