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All optical detectors to date annihilate photons upon detection, thus excluding repeated measurements. Here, we demonstrate a robust photon detection scheme which does not rely on absorption. Instead, an incoming photon is reflected off an…

Quantum Physics · Physics 2013-12-16 Andreas Reiserer , Stephan Ritter , Gerhard Rempe

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

Non-contact measurement of the refractive index and thickness of multilayer biological tissues is of great significance for biomedical applications and can greatly improve medical diagnosis and treatment. In this work, we introduce a…

Optics · Physics 2024-04-19 Yu-Lin Ku , Yao-Gen Shu

Ultra-sensitive short-wave infrared (SWIR) photon detection is a crucial aspect of ongoing research in quantum technology. However, developing such detectors on a CMOS-compatible silicon technological platform has been challenging due to…

Applied Physics · Physics 2024-11-15 P. Sudha , S. Miyagawa , A. Samanta , D. Moraru

The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here…

A new theoretical technique for understanding, analyzing and developing optical systems is presented. The approach is statistical in nature, where information about an object under investigation is discovered, by examining deviations from a…

Optics · Physics 2016-09-20 Damien P. Kelly

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

An ultrafast single-pixel optical 2D imaging system using a single multimode fiber (MF) is proposed. The MF acted as the all-optical random pattern generator. Light with different wavelengths pass through a single MF will generator…

Optical coherence tomography (OCT) has become a favorable device in the Dermatology discipline due to its moderate resolution and penetration depth. OCT images however contain a grainy pattern, called speckle, due to the use of a broadband…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Elaheh Rashedi , Saba Adabi , Darius Mehregan , Silvia Conforto , Xue-wen Chen

Quantum-optical coherence tomography (QOCT) is an optical sectioning modality based on the quantum interference of photon pairs, obtained from a spontaneous parametric downconversion (SPDC) source. The promise of QOCT derives from two…

We propose a novel approach to the important fundamental problem of detecting weak optical fields at the few photon level. The ability to detect with high efficiency (>99%), and to distinguish the number of photons in a given time interval…

Quantum Physics · Physics 2009-11-07 Daniel James , Paul Kwiat

Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

Medical Physics · Physics 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

Retinal Optical Coherence Tomography (OCT) segmentation is essential for diagnosing pathology. Traditional methods focus on either spatial or spectral domains, overlooking their combined dependencies. We propose a triple-encoder network…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Kristin Qi , Xinhan Di

Spectral Domain Optical Coherence Tomography (SD-OCT) is a well-known imaging modality which allows for \textit{in-vivo} visualization of the morphology of different biological tissues at cellular level resolutions. The overall SD-OCT…

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

Improved measurement techniques are central to technological development and foundational scientific exploration. Quantum optics relies upon detectors sensitive to non-classical features of light, enabling precise tests of physical laws and…

Quantum Physics · Physics 2014-07-18 Merlin Cooper , Michal Karpinski , Brian J. Smith

Wedemonstratedeep-learningneuralnetwork(NN)-baseddynamicopticalcoherence tomography (DOCT), which generates high-quality logarithmic-intensity-variance (LIV) DOCT images from only four OCT frames. The NN model is trained for tumor spheroid…

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

By projecting onto complex optical mode profiles, it is possible to estimate arbitrarily small separations between objects with quantum-limited precision, free of uncertainty arising from overlapping intensity profiles. Here we extend these…