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The drug development pipeline for a new compound can last 10-20 years and cost over 10 billion. Drug repurposing offers a more time- and cost-effective alternative. Computational approaches based on biomedical knowledge graph…
Nanoplastics are emerging contaminants that have now transformed into a worldwide environmental concern. It is a lesser-known fact that several emerging contaminants, such as bisphenol and perfluoro alkylates adsorbing on micro and…
We investigate the effect of high temperature treatments followed by only high-pressure water rinse (HPR) of superconducting radio frequency (SRF) niobium cavities. The objective is to provide a cost effective alternative to the typical…
Medical devices with matrix metalloproteinase (MMP) modulating functionality are highly desirable to restore tissue homeostasis in critical inflammation states, such as chronic wounds, rotator cuff tears and cancer. The introduction of…
Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved with the design of 3D implants, which combine the merits of…
Background showers triggered by hadrons represent over 99.9% of all particles arriving at ground-based gamma-ray observatories. An important stage in the data analysis of these observatories, therefore, is the removal of hadron-triggered…
We report herein, the potential of raw pinecone powder (PCP) and pinecone biochar (PCBC) as alternatives to activated carbon used in Permeable Adsorptive Barriers (PABs) for the in situ remediation of polluted groundwater. A constructed…
Nanoporous carbon composite membranes, comprising a layer of porous carbon fiber structures with an average channel width of 30-60 nm grown on a porous ceramic substrate, are found to exhibit robust desalination effect with high freshwater…
Objective: Ficus exasperata Vahl (Sandpaper tree) is extensively used in Nigeria to treat diseases, but a dearth of documentation about its toxicity exists. This information is crucial because pollutants can contaminate medicinal plants.…
Photodynamically active fibres (PAFs) are a novel class of stimulus-sensitive systems capable of triggering antibiotic-free antibacterial effect on-demand when exposed to light. Despite their relevance in infection control, however, the…
Global rice production systems face two opposing challenges: the need to increase production to accommodate the world's growing population while simultaneously reducing greenhouse gas (GHG) emissions. Adaptations to drainage regimes are one…
Monoclonal antibodies constitute one of the most important strategies to treat patients suffering from cancers such as hematological malignancies and solid tumors. In order to guarantee the quality of those preparations prepared at…
Micro-sized cold atmospheric plasma (uCAP) has been developed to expand the applications of CAP in cancer therapy. In this paper, uCAP devices with different nozzle lengths were applied to investigate effects on both brain (glioblastoma…
Retrieval systems are increasingly used in biomedical and clinical natural language processing applications, yet practical guidance for researchers building such systems is limited. In this work, we provide such guidance through an…
The aim of this work is to develop dual-functional scaffolds for bone tissue regeneration and local antibiotic delivery applications. In this respect, bioresorbable bredigite (Ca7MgSi4O16) porous scaffolds were fabricated by a foam replica…
A development effort to improve the performance of superconducting radio-frequency half-wave resonators (SRF HWRs) is underway at the Facility for Rare Isotope Beams (FRIB), where 220 such resonators are in operation. Our goal was to…
Plasma medicine is an emerging and innovative interdisciplinary research field combining biology, chemistry, physics, engineering, and medicine. However, the safe clinical application of cold atmospheric plasma (CAP) technology is still a…
The freshwater crisis is a growing concern and a pressing problem for the world because of the increasing population, civilization, and rapid industrial growth. The water treatment facilities are able to supply less than 1% of the total…
This article investigates a bi-objective redundancy allocation problem (RAP) for repairable systems, defined as cost minimization and availability maximization. Binary decisions jointly select the number of components and the standby…
Hydrothermal liquefaction could potentially utilize mixed plastic wastes for sustainable biocrude production, however the fate of plastics under HTL is largely unexplored for the same reaction conditions. In this study, we evaluate how…