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We consider inference for a collection of partially observed, stochastic, interacting, nonlinear dynamic processes. Each process is identified with a label called its unit, and our primary motivation arises in biological metapopulation…

Methodology · Statistics 2022-12-20 Edward L. Ionides , Ning Ning , Jesse Wheeler

In particle-in-cell simulations, excessive or even unfeasible computational demands can be caused by the growth of the number of particles in the course of prolific ionization or cascaded pair production due to the effects of quantum…

Computational Physics · Physics 2021-01-25 A. Muraviev , A. Bashinov , E. Efimenko , V. Volokitin , I. Meyerov , A. Gonoskov

Modeling the immune system so that its essential functionalities stand out without the need for every molecular or cellular interaction to be taken into account has been challenging for many decades. Two competing approaches have been the…

Cellular Automata and Lattice Gases · Physics 2017-11-13 Kátia K. Cassiano , Valmir C. Barbosa

A major problem in evolutionary biology is how species learn and adapt under the constraint of environmental conditions and competition of other species. Models of cyclic dominance provide simplified settings in which such questions can be…

Statistical Mechanics · Physics 2025-04-09 Honghao Yu , Robert L. Jack

Many events in the vertebrate immune system are influenced by some element of chance. The objective of the present work is to describe affinity maturation of B lymphocytes (in which random events are perhaps the most characteristic), and to…

Molecular Networks · Quantitative Biology 2015-05-05 Tamás Szabados , Gábor Tusnády , László Varga , Tibor Bakács

Implementing Bayesian inference is often computationally challenging in applications involving complex models, and sometimes calculating the likelihood itself is difficult. Synthetic likelihood is one approach for carrying out inference…

Computation · Statistics 2021-03-15 David T. Frazier , David J. Nott , Christopher Drovandi , Robert Kohn

We address the problem of Bayesian reinforcement learning using efficient model-based online planning. We propose an optimism-free Bayes-adaptive algorithm to induce deeper and sparser exploration with a theoretical bound on its performance…

Machine Learning · Computer Science 2020-06-30 Divya Grover , Debabrota Basu , Christos Dimitrakakis

Particle swarm optimization is a popular method for solving difficult optimization problems. There have been attempts to formulate the method in formal probabilistic or stochastic terms (e.g. bare bones particle swarm) with the aim to…

Neural and Evolutionary Computing · Computer Science 2012-11-19 Peter Andras

Particle filtering is a popular method for inferring latent states in stochastic dynamical systems, whose theoretical properties have been well studied in machine learning and statistics communities. In many control problems, e.g.,…

Machine Learning · Computer Science 2021-07-12 Simon S. Du , Wei Hu , Zhiyuan Li , Ruoqi Shen , Zhao Song , Jiajun Wu

Quantifying the outcomes of cells collisions is a crucial step in building the foundations of a kinetic theory of living matter. Here, we develop a mechanical theory of such collisions by first representing individual cells as extended…

Biological Physics · Physics 2019-12-11 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

Bayesian filtering approximates the true underlying behavior of a time-varying system by inverting an explicit generative model to convert noisy measurements into state estimates. This process typically requires either storage, inversion,…

Machine Learning · Computer Science 2023-11-20 Gianluca M. Bencomo , Jake C. Snell , Thomas L. Griffiths

Approximate Bayes Computations (ABC) are used for parameter inference when the likelihood function of the model is expensive to evaluate but relatively cheap to sample from. In particle ABC, an ensemble of particles in the product space of…

Computation · Statistics 2016-04-15 Carlo Albert , Hans R. Kuensch , Andreas Scheidegger

Many organisms and cell types, from bacteria to cancer cells, exhibit a remarkable ability to adapt to fluctuating environments. Additionally, cells can leverage a memory of past environments to better survive previously-encountered…

Machine Learning · Computer Science 2025-01-29 Josiah C. Kratz , Jacob Adamczyk

Membrane systems are a biologically-inspired computational model based on the structure of biological cells and the way chemicals interact and traverse their membranes. Although their dynamics are described by rules, encoding membrane…

Logic in Computer Science · Computer Science 2024-01-17 Rubén Rubio , Narciso Martí-Oliet , Isabel Pita , Alberto Verdejo

We propose the use of Bayesian networks, which provide both a mean value and an uncertainty estimate as output, to enhance the safety of learned control policies under circumstances in which a test-time input differs significantly from the…

Machine Learning · Computer Science 2019-02-18 Keuntaek Lee , Kamil Saigol , Evangelos A. Theodorou

Recursive Bayesian inference, in which posterior beliefs are updated in light of accumulating data, is a tool for implementing Bayesian models in applications with streaming and/or very large data sets. As the posterior of one iteration…

Methodology · Statistics 2025-08-05 Henry R. Scharf

In this paper, we study feedback dynamical systems with memoryless controllers under imperfect information. We develop an algorithm that searches for "adversarial scenarios", which can be thought of as the strategy for the adversary…

Systems and Control · Electrical Eng. & Systems 2021-08-10 Liren Yang , Necmiye Ozay

Smart active particles can acquire some limited knowledge of the fluid environment from simple mechanical cues and exert a control on their preferred steering direction. Their goal is to learn the best way to navigate by exploiting the…

Fluid Dynamics · Physics 2018-05-02 Simona Colabrese , Kristian Gustavsson , Antonio Celani , Luca Biferale

Bayesian filtering deals with computing the posterior distribution of the state of a stochastic dynamic system given noisy observations. In this paper, motivated by applications in counter-adversarial systems, we consider the following…

Systems and Control · Electrical Eng. & Systems 2020-10-28 Robert Mattila , Cristian R. Rojas , Vikram Krishnamurthy , Bo Wahlberg

Security attacks present unique challenges to self-adaptive system design due to the adversarial nature of the environment. However, modeling the system as a single player, as done in prior works in security domain, is insufficient for the…

Artificial Intelligence · Computer Science 2021-03-17 Mingyue Zhang