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Bayesian Filtering for plan and activity recognition is challenging for scenarios that contain many observation equivalent entities (i.e. entities that produce the same observations). This is due to the combinatorial explosion in the number…

Artificial Intelligence · Computer Science 2017-08-15 Max Schröder , Stefan Lüdtke , Sebastian Bader , Frank Krüger , Thomas Kirste

Learning about the causal structure of the world is a fundamental problem for human cognition. Causal models and especially causal learning have proved to be difficult for large pretrained models using standard techniques of deep learning.…

Artificial Intelligence · Computer Science 2026-04-16 Eunice Yiu , Kelsey Allen , Shiry Ginosar , Alison Gopnik

We consider the mutual interactions, via cytokine exchanges, among helper lymphocytes, B lymphocytes and killer lymphocytes, and we model them as a unique system by means of a tripartite network. Each part includes all the different clones…

Biological Physics · Physics 2015-03-19 Elena Agliari , Adriano Barra , Francesco Guerra , Francesco Moauro

Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

All biological and artificial agents must learn and make decisions given limits on their ability to process information. As such, a general theory of adaptive behavior should be able to account for the complex interactions between an…

Machine Learning · Computer Science 2023-05-08 Dilip Arumugam , Mark K. Ho , Noah D. Goodman , Benjamin Van Roy

The similarity between neural and immune networks has been known for decades, but so far we did not understand the mechanism that allows the immune system, unlike associative neural networks, to recall and execute a large number of…

Disordered Systems and Neural Networks · Physics 2017-03-20 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

Simulation is a useful tool in situations where training data for machine learning models is costly to annotate or even hard to acquire. In this work, we propose a reinforcement learning-based method for automatically adjusting the…

Machine Learning · Computer Science 2019-05-15 Nataniel Ruiz , Samuel Schulter , Manmohan Chandraker

Simple memorizing tasks have been chosen such as a binary code on a matrix. After the establishment of an appropriate protocol, the codified matrices were individually presented to 150 university students who had to memorize them. A…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexandra C. Tsallis , Constantino Tsallis , Aglae C. N. de Magalhaes , Francisco A. Tamarit

Strategies for sustaining cooperation and preventing exploitation by selfish agents in repeated games have mostly been restricted to Markovian strategies where the response of an agent depends on the actions in the previous round. Such…

Populations and Evolution · Quantitative Biology 2023-10-30 Arunava Patra , Supratim Sengupta , Ayan Paul , Sagar Chakraborty

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Within the germinal center in follicles, B-cells proliferate, mutate and differentiate, while being submitted to a powerful selection~: a micro-evolutionary mechanism at the heart of adaptive immunity. A new foreign pathogen is confronted…

Probability · Mathematics 2016-02-12 Irene Balelli , Vuk Milisic , Gilles Wainrib

A central goal of synthetic biology is to design sophisticated synthetic cellular circuits that can perform complex computations and information processing tasks in response to specific inputs. The tremendous advances in our ability to…

Molecular Networks · Quantitative Biology 2016-02-17 Pankaj Mehta , Alex H. Lang , David J. Schwab

System identification of complex and nonlinear systems is a central problem for model predictive control and model-based reinforcement learning. Despite their complexity, such systems can often be approximated well by a set of linear…

Machine Learning · Statistics 2019-05-30 Philip Becker-Ehmck , Jan Peters , Patrick van der Smagt

Innovation in synthetic biology often still depends on large-scale experimental trial-and-error, domain expertise, and ingenuity. The application of rational design engineering methods promise to make this more efficient, faster, cheaper…

Molecular Networks · Quantitative Biology 2021-08-18 Robyn P. Araujo , Sean T. Vittadello , Michael P. H. Stumpf

We study \emph{partial-information} two-player turn-based games on graphs with omega-regular objectives, when the partial-information player has \emph{limited memory}. Such games are a natural formalization for reactive synthesis when the…

Formal Languages and Automata Theory · Computer Science 2020-02-19 Dhananjay Raju , Rüdiger Ehlers , Ufuk Topcu

In the game-theoretic approach to controller synthesis, we model the interaction between a system to be controlled and its environment as a game between these entities, and we seek an appropriate (e.g., winning or optimal) strategy for the…

Logic in Computer Science · Computer Science 2025-09-05 Mickael Randour

Particle and ensemble filters are increasingly utilized for inference, optimization, and forecast; however, both filtering methods use discrete distributions to simulate continuous state space, a drawback that can lead to degraded…

Methodology · Statistics 2014-03-27 Wan Yang , Jeffrey Shaman

When subjected to automated decision-making, decision subjects may strategically modify their observable features in ways they believe will maximize their chances of receiving a favorable decision. In many practical situations, the…

Computer Science and Game Theory · Computer Science 2022-10-10 Keegan Harris , Valerie Chen , Joon Sik Kim , Ameet Talwalkar , Hoda Heidari , Zhiwei Steven Wu

Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not…

Quantitative Methods · Quantitative Biology 2010-01-20 Tina Toni , Michael P. H. Stumpf

Cells process external and internal signals through chemical interactions. Cells that constitute the immune system (e.g., antigen presenting cell, T-cell, B-cell, mast cell) can have different functions (e.g., adaptive memory, inflammatory…

Molecular Networks · Quantitative Biology 2017-09-21 John A. P. Sekar , James R. Faeder