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Null hypothesis significance tests and p values are widely used despite very strong arguments against their use in many contexts. Confidence intervals are often recommended as an alternative, but these do not achieve the objective of…

Methodology · Statistics 2014-02-12 Michael Wood

We are concerned with testing replicability hypotheses for many endpoints simultaneously. This constitutes a multiple test problem with composite null hypotheses. Traditional $p$-values, which are computed under least favourable parameter…

Methodology · Statistics 2020-02-26 Anh-Tuan Hoang , Thorsten Dickhaus

In many common situations, a Bayesian credible interval will be, given the same data, very similar to a frequentist confidence interval, and researchers will interpret these intervals in a similar fashion. However, no predictable similarity…

Statistics Theory · Mathematics 2023-04-25 Harlan Campbell , Paul Gustafson

Increased availability of data and accessibility of computational tools in recent years have created unprecedented opportunities for scientific research driven by statistical analysis. Inherent limitations of statistics impose constrains on…

Genomics · Quantitative Biology 2016-09-13 Olga A. Vsevolozhskaya , Gabriel Ruiz , Dmitri V. Zaykin

It is well known that there is no direct one-to-one relation between $p$-values and likelihood ratios or Bayes factors, since their relation crucially involves the sample size $n$. We investigate their (asymptotic) relation in a…

Statistics Theory · Mathematics 2026-03-23 Wouter Kager , Ronald Meester

This article addresses issues of model criticism and model comparison in Bayesian contexts, and focusses on the use of the so-called posterior predictive p-values (ppp values). These involve a general discrepancy or conflict measure and…

Methodology · Statistics 2026-05-26 Nils Lid Hjort , Fredrik A. Dahl , Gunnhildur Högnadóttir Steinbakk

I proposed (8, 1, 3) that p values should be supplemented by an estimate of the false positive risk (FPR). FPR was defined as the probability that, if you claim that there is a real effect on the basis of p value from a single unbiased…

Other Statistics · Statistics 2020-08-10 David Colquhoun

When researchers carry out a null hypothesis significance test, it is tempting to assume that a statistically significant result lowers Prob(H0), the probability of the null hypothesis being true. Technically, such a statement is…

Applications · Statistics 2022-04-19 Daniel J. Schad , Shravan Vasishth

For situations where we are trying to decide which of two hypotheses $H_{0}$ and $H_{1}$ provides a better description of some data, we discuss the usefulness of plots of $p_{0}$ versus $p_{1}$, where $p_{i}$ is the $p$-value for testing…

Methodology · Statistics 2014-08-27 Luc Demortier , Louis Lyons

Two-sided statistical tests and p-values are well defined only when the test statistic in question has a symmetric distribution. A new two-sided p-value called conditional p-value $P_C$ is introduced here. It is closely related to the…

Statistics Theory · Mathematics 2008-10-14 Elena Kulinskaya

Since its debut in the 18th century, the P-value has been an important part of hypothesis testing-based scientific discoveries. As the statistical engine accelerates, questions are beginning to be raised, asking to what extent scientific…

In many hypothesis testing applications, we have mixed priors, with well-motivated informative priors for some parameters but not for others. The Bayesian methodology uses the Bayes factor and is helpful for the informative priors, as it…

Data Analysis, Statistics and Probability · Physics 2022-10-05 Jakob Robnik , Uroš Seljak

We consider the problem of comparing two Poisson parameters from the Bayesian perspective. Kawasaki and Miyaoka (2012b) proposed the Bayesian index $P(\lambda_1 < \lambda_2 | X_1,X_2)$ and expressed it using the hypergeometric series. In…

Methodology · Statistics 2016-06-07 Masaaki Doi

Correlated proportions arise in longitudinal (panel) studies. A typical example is the ``opinion swing'' problem: ``Has the proportion of people favoring a politician changed after his recent speech to the nation on TV?''. Since the same…

Statistics Theory · Mathematics 2007-07-27 Guido Consonni , Luca La Rocca

A new computation method of frequentist $p$-values and Bayesian posterior probabilities based on the bootstrap probability is discussed for the multivariate normal model with unknown expectation parameter vector. The null hypothesis is…

Methodology · Statistics 2013-12-24 Hidetoshi Shimodaira

Null hypothesis statistical significance testing (NHST) is the dominant approach for evaluating results from randomized controlled trials. Whereas NHST comes with long-run error rate guarantees, its main inferential tool -- the $p$-value --…

Methodology · Statistics 2022-06-10 František Bartoš , Samuel Pawel , Eric-Jan Wagenmakers

The null hypothesis test (NHT) is widely used for validating scientific hypotheses but is actually highly criticized. Although Bayesian tests overcome several criticisms, some limits remain. We propose a Bayesian two-interval test (2IT) in…

Methodology · Statistics 2021-07-06 Nicolas Meyer , Erik-André Sauleau

The randomized $p$-value, (nonrandomized) mid-$p$-value and abstract randomized $p$-value have all been recommended for testing a null hypothesis whenever the test statistic has a discrete distribution. This paper provides a unifying…

Computation · Statistics 2014-12-02 Joshua D Habiger

The American Statistical Association (ASA) statement on statistical significance and P-values \cite{wasserstein2016asa} cautioned statisticians against making scientific decisions solely on the basis of traditional P-values. The statement…

Methodology · Statistics 2024-02-22 Abhisek Chakraborty , Megan H. Murray , Ilya Lipkovich , Yu Du

Bayesian and frequentist criteria fundamentally differ, but often posterior and sampling distributions agree asymptotically (e.g., Gaussian with same covariance). For the corresponding single-draw experiment, we characterize the frequentist…

Statistics Theory · Mathematics 2024-07-04 David M. Kaplan , Longhao Zhuo