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Biochemical oscillations are ubiquitous in nature and allow organisms to properly time their biological functions. In this paper, we consider minimal Markov state models of nonequilibrium biochemical networks that support oscillations. We…

Statistical Mechanics · Physics 2020-02-04 Clara del Junco , Suriyanarayanan Vaikuntanathan

We employ an equivalent-circuit model of a multi-cell cavity to explore its time-dependent behavior in order to understand differences between the multi-cell model and the commonly-used model of a single-cell resonator. Furthermore, we…

Accelerator Physics · Physics 2026-02-27 Volker Ziemann

Bosonic encoding is an approach for quantum information processing, promising lower hardware overhead by encoding in the many levels of a harmonic oscillator mode. Scaling to multiple modes requires weak interaction for independent control,…

Quantum Physics · Physics 2024-04-04 Asaf A. Diringer , Eliya Blumenthal , Avishay Grinberg , Liang Jiang , Shay Hacohen-Gourgy

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

Cell Behavior · Quantitative Biology 2019-07-08 Shou-Wen Wang , Lei-Han Tang

This paper generalizes recent results by the authors on noninvasive model-reference adaptive control designs for control-based continuation of periodic orbits in periodically excited linear systems with matched uncertainties to a larger…

Optimization and Control · Mathematics 2023-01-02 Yang Li , Harry Dankowicz

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

Biological Physics · Physics 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

Systems with the coexistence of different stable attractors are widely exploited in systems biology in order to suitably model the differentiating processes arising in living cells. In order to describe genetic regulatory networks several…

Dynamical Systems · Mathematics 2010-07-16 V. Lanza , L. Ponta , M. Bonnin , F. Corinto

We investigate a driven, one-dimensional system of colloidal particles in a periodically currogated narrow channel subject to a time-delayed feedback control. Our goal is to identify conditions under which the control induces oscillatory,…

Soft Condensed Matter · Physics 2015-06-11 Ken Lichtner , Andrey Pototsky , Sabine H. L. Klapp

Oscillatory gene circuits are ubiquitous to biology and are involved in fundamental processes of cell cycle, circadian rhythms and developmental systems. The synthesis of small, non-natural oscillatory genetic circuits have been…

Molecular Networks · Quantitative Biology 2020-02-05 Yash Joshi , Yash Kiran Jawale , Chaitanya Anil Athale

A composite, exponential relaxation function, modulated by a periodic component, was used to fit to an experimental time series of blood glucose levels. The 11 parameters function that allows for the detection of a possible rhythm…

Quantitative Methods · Quantitative Biology 2008-01-30 Baruch Vainas

The main objective of quantum simulation is an in-depth understanding of many-body physics. It is important for fundamental issues (quantum phase transitions, transport, . . . ) and for the development of innovative materials. Analytic…

Transport of ions and small molecules across the cell membrane against electrochemical gradients is catalyzed by integral membrane proteins that use a source of free energy to drive the energetically uphill flux of the transported…

Biomolecules · Quantitative Biology 2022-03-25 Oliver Beckstein , Fiona Naughton

Reservoir computing is a machine learning framework that uses artificial or physical dissipative dynamics to predict time-series data using nonlinearity and memory properties of dynamical systems. Quantum systems are considered as promising…

We propose a new dynamical method to connect equilibrium quantum phase transitions and quantum coherence using out-of-time-order correlations (OTOCs). Adopting the iconic Lipkin-Meshkov-Glick and transverse-field Ising models as…

Quantum Physics · Physics 2020-12-21 Robert J. Lewis-Swan , Sean R. Muleady , Ana Maria Rey

We have studied theoretically the basic operation of a quantum feedback loop designed to maintain the desired phase of quantum coherent oscillations in a two-level system. Such feedback can suppress the dephasing of oscillations due to…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Rusko Ruskov , Alexander N. Korotkov

We analyse the effect of intrinsic fluctuations on the properties of bistable stochastic systems with time scale separation operating under1 quasi-steady state conditions. We first formulate a stochastic generalisation of the quasi-steady…

Biological Physics · Physics 2016-03-02 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Classically integrable approximants are here constructed for a family of predominantly chaotic periodic systems by means of the Baker-Hausdorff-Campbell formula. We compare the evolving wave density for the corresponding exact quantum…

Chaotic Dynamics · Physics 2020-05-26 Gabriel M. Lando , Alfredo M. Ozorio de Almeida

In genomic applications, there is often interest in identifying genes whose time-course expression trajectories exhibit periodic oscillations with a period of approximately 24 hours. Such genes are usually referred to as circadian, and…

Methodology · Statistics 2024-02-28 Silvia Montagna , Irina Irincheeva , Surya T. Tokdar

Post-transductional modifications tune the functions of proteins and regulate the collective dynamics of biochemical networks that determine how cells respond to environmental signals. For example, protein phosphorylation and nitrosylation…

Cell Behavior · Quantitative Biology 2009-11-13 Roberto Chignola , Chiara Dalla Pellegrina , Alessio Del Fabbro , Edoardo Milotti

Finite systems of bosons and/or fermions described by the Hubbard model can be realized using ultracold atoms confined in optical lattices. The ground states of these systems often exhibit a coexistence of compressible superfluid and…

Quantum Gases · Physics 2015-07-24 Sunil Yeshwanth , Marcos Rigol , Stephan Haas , Lorenzo Campos Venuti