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This reply is in response to commentaries by Barnett, Barrett, and Seth (arXiv:1708.08001) and Faes, Stramaglia, and Marinazzo (arXiv:1708.06990) on our paper entitled "A study of problems encountered in Granger causality analysis from a…

Methodology · Statistics 2017-10-02 Patrick A. Stokes , Patrick L. Purdon

Granger causal inference is a contentious but widespread method used in fields ranging from economics to neuroscience. The original definition addresses the notion of causality in time series by establishing functional dependence…

Methodology · Statistics 2023-09-19 Noah D. Gade , Jordan Rodu

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

Neurons and Cognition · Quantitative Biology 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

We consider the problem of inferring the directed, causal graph from observational data, assuming no hidden confounders. We take an information theoretic approach, and make three main contributions. First, we show how through algorithmic…

Machine Learning · Statistics 2018-09-07 Alexander Marx , Jilles Vreeken

Understanding the dynamic nature of brain connectivity is critical for elucidating neural processing, behavior, and brain disorders. Traditional approaches such as sliding-window correlation (SWC) characterize time-varying undirected…

Neurons and Cognition · Quantitative Biology 2026-02-19 Nan Xu , Xiaodi Zhang , Wen-Ju Pan , Jeremy L. Smith , Eric H. Schumacher , Jason W. Allen , Vince D. Calhoun , Shella D. Keilholz

Time-series forecasting and causal discovery are central in neuroscience, as predicting brain activity and identifying causal relationships between neural populations and circuits can shed light on the mechanisms underlying cognition and…

Machine Learning · Computer Science 2025-09-18 Alessandro Crimi , Andrea Brovelli

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Granger causality is well established within the neurosciences for inference of directed functional connectivity from neurophysiological data. These data usually consist of time series which subsample a continuous-time biophysiological…

Applications · Statistics 2016-09-08 Lionel Barnett , Anil K. Seth

Human Activity Recognition using wearable inertial sensors is foundational to healthcare monitoring, fitness analytics, and context-aware computing, yet its deployment is hindered by cross-user variability arising from heterogeneous…

Machine Learning · Computer Science 2026-03-18 Xiaozhou Ye , Feng Jiang , Zihan Wang , Xiulai Wang , Yutao Zhang , Kevin I-Kai Wang

Federated Graph Learning (FGL) has emerged as a powerful paradigm for decentralized training of graph neural networks while preserving data privacy. However, existing FGL methods are predominantly designed for static graphs and rely on…

Machine Learning · Computer Science 2026-04-01 Yuxuan Liu , Wenchao Xu , Haozhao Wang , Zhiming He , Zhaofeng Shi , Chongyang Xu , Peichao Wang , Boyuan Zhang

Granger causality recovers directed interactions from time-series data, but in many distributed systems, the data are vertically partitioned across clients, with each client observing only the variables of its own subsystem. Federated…

Machine Learning · Computer Science 2026-05-13 Ayush Mohanty , Nazal Mohamed , Nagi Gebraeel

Recently, there has been a revived interest in system neuroscience causation models due to their unique capability to unravel complex relationships in multi-scale brain networks. In this paper, our goal is to verify the feasibility and…

Machine Learning · Computer Science 2024-09-30 Dachuan Song , Li Shen , Duy Duong-Tran , Xuan Wang

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

Causality has the potential to truly transform the way we solve a large number of real-world problems. Yet, so far, its potential largely remains to be unlocked as causality often requires crucial assumptions which cannot be tested in…

Machine Learning · Computer Science 2024-02-15 Jeroen Berrevoets , Krzysztof Kacprzyk , Zhaozhi Qian , Mihaela van der Schaar

While probabilistic models describe the dependence structure between observed variables, causal models go one step further: they predict, for example, how cognitive functions are affected by external interventions that perturb neuronal…

Neurons and Cognition · Quantitative Biology 2021-04-12 Sebastian Weichwald , Jonas Peters

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Modern brain imaging technologies have enabled the detailed reconstruction of human brain connectomes, capturing structural connectivity (SC) from diffusion MRI and functional connectivity (FC) from functional MRI. Understanding the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Yee-Fan Tan , Jun Lin Liow , Pei-Sze Tan , Fuad Noman , Raphael C. -W. Phan , Hernando Ombao , Chee-Ming Ting

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett
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