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While correlation measures are used to discern statistical relationships between observed variables in almost all branches of data-driven scientific inquiry, what we are really interested in is the existence of causal dependence. Designing…

Machine Learning · Computer Science 2014-06-26 Ishanu Chattopadhyay

We implement the dynamical Ising model on the large scale architecture of white matter connections of healthy subjects in the age range 4-85 years, and analyze the dynamics in terms of the synergy, a quantity measuring the extent to which…

Neurons and Cognition · Quantitative Biology 2020-05-15 Davide Nuzzi , Mario Pellicoro , Leonardo Angelini , Daniele Marinazzo , Sebastiano Stramaglia

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Patterns of brain activity are associated with different brain processes and can be used to identify different brain states and make behavioral predictions. However, the relevant features are not readily apparent and accessible. To mine…

In this work, we propose a novel generative method to identify the causal impact and apply it to prediction tasks. We conduct causal impact analysis using interventional and counterfactual perspectives. First, applying interventions, we…

Machine Learning · Computer Science 2025-09-03 Soma Bandyopadhyay , Sudeshna Sarkar

This paper explores the potential of the transformer models for learning Granger causality in networks with complex nonlinear dynamics at every node, as in neurobiological and biophysical networks. Our study primarily focuses on a…

Machine Learning · Computer Science 2025-10-21 Ziyu Lu , Anika Tabassum , Shruti Kulkarni , Lu Mi , J. Nathan Kutz , Eric Shea-Brown , Seung-Hwan Lim

Characterising cause-effect relationships in complex systems is fundamental to understanding their underlying mechanisms. Granger causality (GC) remains a widely used computational tool for identifying causal relationships in time series…

Machine Learning · Statistics 2026-05-26 S. A. Adedayo

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Feature selection is a crucial preprocessing step in data analytics and machine learning. Classical feature selection algorithms select features based on the correlations between predictive features and the class variable and do not attempt…

Machine Learning · Computer Science 2019-11-19 Kui Yu , Xianjie Guo , Lin Liu , Jiuyong Li , Hao Wang , Zhaolong Ling , Xindong Wu

Recently, there have been several concerted international efforts - the BRAIN initiative, European Human Brain Project and the Human Connectome Project, to name a few - that hope to revolutionize our understanding of the connected brain.…

Neurons and Cognition · Quantitative Biology 2016-02-10 Adeel Razi , Karl Friston

Event Causality Extraction (ECE) aims at extracting causal event pairs from texts. Despite ChatGPT's recent success, fine-tuning small models remains the best approach for the ECE task. However, existing fine-tuning based ECE methods cannot…

Computation and Language · Computer Science 2024-08-07 Jinglong Gao , Chen Lu , Xiao Ding , Zhongyang Li , Ting Liu , Bing Qin

In clinical practice, the robustness of deep learning models for multimodal brain tumor segmentation is severely compromised by incomplete MRI data. This vulnerability stems primarily from modality bias, where models exploit spurious…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Bo Liu , Yulong Zou , Jin Hong

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

Federated causal discovery aims to uncover the causal relationships between entities while protecting data privacy, which has significant importance and numerous applications in real-world scenarios. Existing federated causal structure…

Machine Learning · Computer Science 2025-07-10 Wei Chen , Wanyang Gu , Linjun Peng , Ruichu Cai , Zhifeng Hao , Kun Zhang

Most neural models of causality assume static causal graphs, failing to capture the dynamic and sparse nature of physical interactions where causal relationships emerge and dissolve over time. We introduce the Causal Process Framework and…

Machine Learning · Computer Science 2026-04-07 Turan Orujlu , Christian Gumbsch , Martin V. Butz , Charley M Wu

Brain functional connectivity (FC), the temporal synchrony between brain networks, is essential to understand the functional organization of the brain and to identify changes due to neurological disorders, development, treatment, and other…

Applications · Statistics 2025-06-18 Amanda Mejia , David Bolin , Daniel Spencer , Ani Eloyan

Many large-scale applications can be elegantly represented using graph structures. Their scalability, however, is often limited by the domain knowledge required to apply them. To address this problem, we propose a novel Causal Temporal…

Machine Learning · Computer Science 2023-03-20 Abigail Langbridge , Fearghal O'Donncha , Amadou Ba , Fabio Lorenzi , Christopher Lohse , Joern Ploennigs

Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional…

Traditional machine learning and deep learning techniques rely on correlation-based learning, often failing to distinguish spurious associations from true causal relationships, which limits robustness, interpretability, and…

Machine Learning · Computer Science 2025-03-05 Emam Hossain , Muhammad Hasan Ferdous , Jianwu Wang , Aneesh Subramanian , Md Osman Gani

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu
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