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Graph Convolution Networks (GCNs) have significantly succeeded in learning user and item representations for recommendation systems. The core of their efficacy is the ability to explicitly exploit the collaborative signals from both the…

Information Retrieval · Computer Science 2024-11-11 Fan Liu , Shuai Zhao , Zhiyong Cheng , Liqiang Nie , Mohan Kankanhalli

Microbes are essentially yet convolutedly linked with human lives on the earth. They critically interfere in different physiological processes and thus influence overall health status. Studying microbial species is used to be constrained to…

Genomics · Quantitative Biology 2021-09-03 Chao Yang , Debajyoti Chowdhury , Zhenmiao Zhang , William K. Cheung , Aiping Lu , Zhao Xiang Bian , Lu Zhang

Continual learning aims to enable machine learning models to learn a general solution space for past and future tasks in a sequential manner. Conventional models tend to forget the knowledge of previous tasks while learning a new task, a…

Machine Learning · Computer Science 2019-04-25 Yu Chen , Tom Diethe , Neil Lawrence

Previous gait recognition methods primarily trained on labeled datasets, which require painful labeling effort. However, using a pre-trained model on a new dataset without fine-tuning can lead to significant performance degradation. So to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xuqian Ren , Shaopeng Yang , Saihui Hou , Chunshui Cao , Xu Liu , Yongzhen Huang

Mycotoxins, toxic secondary metabolites produced by certain fungi, pose significant threats to global food safety and public health. These compounds can contaminate a variety of crops, leading to economic losses and health risks to both…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan Inglis , Andrew Parnell , Natarajan Subramani , Fiona Doohan

Background: Significance analysis plays a major role in identifying and ranking genes, transcription factor binding sites, DNA methylation regions, and other high-throughput features for association with disease. We propose a new approach,…

Methodology · Statistics 2017-01-10 Andrew E. Jaffe , John D. Storey , Hongkai Ji , Jeffrey T. Leek

Deep learning is emerging as an effective tool in drug discovery, with potential applications in both predictive and generative models. Generative Flow Networks (GFlowNets/GFNs) are a recently introduced method recognized for the ability to…

Machine Learning · Computer Science 2023-11-08 Elaine Lau , Nikhil Vemgal , Doina Precup , Emmanuel Bengio

Reasoning about hypotheses and updating knowledge through empirical observations are central to scientific discovery. In this work, we applied logic-based machine learning methods to drive biological discovery by guiding experimentation.…

Molecular Networks · Quantitative Biology 2025-06-09 Lun Ai , Stephen H. Muggleton , Shi-Shun Liang , Geoff S. Baldwin

Traditionally, diagnosis and treatment of fungal infections in humans depend heavily on face-to-face consultations or examinations made by specialized laboratory scientists known as mycologists. In many cases, such as the recent…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Camilo Javier Pineda Sopo , Farshid Hajati , Soheila Gheisari

Feature selection aims to identify the most pattern-discriminative feature subset. In prior literature, filter (e.g., backward elimination) and embedded (e.g., Lasso) methods have hyperparameters (e.g., top-K, score thresholding) and tie to…

Machine Learning · Computer Science 2024-03-07 Wangyang Ying , Dongjie Wang , Haifeng Chen , Yanjie Fu

Feature selection is a core area of data mining with a recent innovation of graph-driven unsupervised feature selection for linked data. In this setting we have a dataset $\mathbf{Y}$ consisting of $n$ instances each with $m$ features and a…

Machine Learning · Computer Science 2020-07-07 Zilong Bai , Hoa Nguyen , Ian Davidson

Graph neural networks (GNNs) have achieved extraordinary enhancements in various areas including the fields medical imaging and network neuroscience where they displayed a high accuracy in diagnosing challenging neurological disorders such…

Machine Learning · Computer Science 2022-09-14 Mehmet Yigit Balik , Arwa Rekik , Islem Rekik

Biclustering is an unsupervised machine-learning approach aiming to cluster rows and columns simultaneously in a data matrix. Several biclustering algorithms have been proposed for handling numeric datasets. However, real-world data mining…

Machine Learning · Computer Science 2024-08-26 Adán José-García , Julie Jacques , Clément Chauvet , Vincent Sobanski , Clarisse Dhaenens

Training generative models like Generative Adversarial Network (GAN) is challenging for noisy data. A novel curriculum learning algorithm pertaining to clustering is proposed to address this issue in this paper. The curriculum construction…

Machine Learning · Computer Science 2019-09-27 Deli Zhao , Jiapeng Zhu , Zhenfang Guo , Bo Zhang

Bacterial cells are sensitive to a range of external signals used to learn the environment. These incoming external signals are then processed using a Gene Regulatory Network (GRN), exhibiting similarities to modern computing algorithms. An…

Molecular Networks · Quantitative Biology 2023-01-12 Samitha Somathilaka , Daniel P. Martins , Xu Li , Yusong Li , Sasitharan Balasubramaniam

Efficient and robust data clustering remains a challenging task in the field of data analysis. Recent efforts have explored the integration of granular-ball (GB) computing with clustering algorithms to address this challenge, yielding…

Machine Learning · Computer Science 2024-05-16 Zihang Jia , Zhen Zhang , Witold Pedrycz

When simulating metabolite productions with genome-scale constraint-based metabolic models, gene deletion strategies are necessary to achieve growth-coupled production, which means cell growth and target metabolite production occur…

Quantitative Methods · Quantitative Biology 2025-11-18 Ziwei Yang , Takeyuki Tamura

Learning ensembles by bagging can substantially improve the generalization performance of low-bias, high-variance estimators, including those evolved by Genetic Programming (GP). To be efficient, modern GP algorithms for evolving (bagging)…

Neural and Evolutionary Computing · Computer Science 2021-02-08 Marco Virgolin

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

In this paper, we consider a real-world scenario where a model that is trained on pre-defined classes continually encounters unlabeled data that contains both known and novel classes. The goal is to continually discover novel classes while…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yanan Wu , Zhixiang Chi , Yang Wang , Songhe Feng