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We introduce a new approach to functional causal modeling from observational data, called Causal Generative Neural Networks (CGNN). CGNN leverages the power of neural networks to learn a generative model of the joint distribution of the…

Synthetic microbiomes offer new possibilities for modulating microbiota, to address the barriers in multidtug resistance (MDR) research. We present a Bayesian optimization approach to enable efficient searching over the space of synthetic…

Quantitative Methods · Quantitative Biology 2024-05-02 Nisha Pillai , Bindu Nanduri , Michael J Rothrock , Zhiqian Chen , Mahalingam Ramkumar

Biclustering has gained interest in gene expression data analysis due to its ability to identify groups of samples that exhibit similar behaviour in specific subsets of genes (or vice versa), in contrast to traditional clustering methods…

Applications · Statistics 2024-12-12 Luis A. Vargas-Mieles , Paul D. W. Kirk , Chris Wallace

Self-supervised learning excels at learning representations from large amounts of data. At the same time, generative models offer the complementary property of learning information about the underlying data generation process. In this…

Machine Learning · Computer Science 2025-08-15 Emanuele Sansone , Robin Manhaeve

Machine learning (ML) classifiers always benefit from more informative input features. We seek to auto-generate stronger feature sets in order to address the difficulty that ML methods often experience given limited training data. A wide…

Emerging Technologies · Computer Science 2020-09-15 Charles B Delahunt , J Nathan Kutz

The performance of multi-task learning in Convolutional Neural Networks (CNNs) hinges on the design of feature sharing between tasks within the architecture. The number of possible sharing patterns are combinatorial in the depth of the…

Computer Vision and Pattern Recognition · Computer Science 2019-08-27 Felix J. S. Bragman , Ryutaro Tanno , Sebastien Ourselin , Daniel C. Alexander , M. Jorge Cardoso

This paper introduces aggregate Bayesian Causal Forests (aBCF), a new Bayesian model for causal inference using aggregated data. Aggregated data are common in policy evaluations where we observe individuals such as students, but…

Determining subgroups that respond especially well (or poorly) to specific interventions (medical or policy) requires new supervised learning methods tailored specifically for causal inference. Bayesian Causal Forest (BCF) is a recent…

Machine Learning · Statistics 2022-09-16 Nikolay Krantsevich , Jingyu He , P. Richard Hahn

Continual Generalized Category Discovery (C-GCD) faces a critical challenge: incrementally learning new classes from unlabeled data streams while preserving knowledge of old classes. Existing methods struggle with catastrophic forgetting,…

Machine Learning · Computer Science 2025-07-24 Hao Dai , Jagmohan Chauhan

Generative Flow Networks (GFlowNets), a new family of probabilistic samplers, have recently emerged as a promising framework for learning stochastic policies that generate high-quality and diverse objects proportionally to their rewards.…

Machine Learning · Computer Science 2024-06-05 Chunhui Li , Cheng-Hao Liu , Dianbo Liu , Qingpeng Cai , Ling Pan

Generalized category discovery (GCD) is a recently proposed open-world problem, which aims to automatically cluster partially labeled data. The main challenge is that the unlabeled data contain instances that are not only from known…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Nan Pu , Zhun Zhong , Nicu Sebe

Genetic variants (GVs) are defined as differences in the DNA sequences among individuals and play a crucial role in diagnosing and treating genetic diseases. The rapid decrease in next generation sequencing cost has led to an exponential…

Machine Learning · Computer Science 2024-12-06 Zehui Li , Vallijah Subasri , Guy-Bart Stan , Yiren Zhao , Bo Wang

Recent methods utilize graph contrastive Learning within graph-structured user-item interaction data for collaborative filtering and have demonstrated their efficacy in recommendation tasks. However, they ignore that the difference relation…

Information Retrieval · Computer Science 2024-03-25 Jiaheng Yu , Jing Li , Yue He , Kai Zhu , Shuyi Zhang , Wen Hu

Generative Bayesian Filtering (GBF) provides a powerful and flexible framework for performing posterior inference in complex nonlinear and non-Gaussian state-space models. Our approach extends Generative Bayesian Computation (GBC) to…

Methodology · Statistics 2025-11-07 Edoardo Marcelli , Sean O'Hagan , Veronika Rockova

Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

Unsupervised clustering has broad applications in data stratification, pattern investigation and new discovery beyond existing knowledge. In particular, clustering of bioactive molecules facilitates chemical space mapping,…

Recommender systems (RecSys) are essential for online platforms, providing personalized suggestions to users within a vast sea of information. Self-supervised graph learning seeks to harness high-order collaborative filtering signals…

Information Retrieval · Computer Science 2025-07-18 Weizhi Zhang , Liangwei Yang , Zihe Song , Henrry Peng Zou , Ke Xu , Yuanjie Zhu , Philip S. Yu

Session-based recommendation systems(SBRS) are more suitable for the current e-commerce and streaming media recommendation scenarios and thus have become a hot topic. The data encountered by SBRS is typically highly sparse, which also…

Information Retrieval · Computer Science 2023-08-31 Zihan Wang , Gang Wu , Haotong Wang

Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

Computational Engineering, Finance, and Science · Computer Science 2013-03-04 G. Prat , Ll. Belanche

By treating users' interactions as a user-item graph, graph learning models have been widely deployed in Collaborative Filtering(CF) based recommendation. Recently, researchers have introduced Graph Contrastive Learning(GCL) techniques into…

Information Retrieval · Computer Science 2023-07-12 Yonghui Yang , Zhengwei Wu , Le Wu , Kun Zhang , Richang Hong , Zhiqiang Zhang , Jun Zhou , Meng Wang
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