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Recent works have demonstrated the superiority of supervised Convolutional Neural Networks (CNNs) in learning hierarchical representations from time series data for successful classification. These methods require sufficiently large labeled…

Machine Learning · Computer Science 2023-09-12 Fanling Huang , Yangdong Deng

Retrosynthesis prediction is one of the fundamental challenges in organic chemistry and related fields. The goal is to find reactants molecules that can synthesize product molecules. To solve this task, we propose a new graph-to-graph…

Quantitative Methods · Quantitative Biology 2022-04-20 Zaiyun Lin , Shiqiu Yin , Lei Shi , Wenbiao Zhou , YingSheng Zhang

Graph collaborative filtering (GCF) has gained considerable attention in recommendation systems by leveraging graph learning techniques to enhance collaborative filtering (CF). One classical approach in GCF is to learn user and item…

Information Retrieval · Computer Science 2024-04-09 Xiangmeng Wang , Qian Li , Dianer Yu , Wei Huang , Guandong Xu

The discovery of functional molecules is an expensive and time-consuming process, exemplified by the rising costs of small molecule therapeutic discovery. One class of techniques of growing interest for early-stage drug discovery is de novo…

Quantitative Methods · Quantitative Biology 2020-02-18 Wenhao Gao , Connor W. Coley

Federated learning faces increasing threats from model poisoning attacks, which harms its application to improve privacy. Existing defense methods typically rely on fixed thresholds or perform clustering with a fixed number of clusters to…

Cryptography and Security · Computer Science 2026-05-22 Tianyun Zhang , Zhen Yang , Haozhao Wang , Ru Zhang , Yongfeng Huang

Supervised learning, characterized by both discriminative and generative learning, seeks to predict the values of single (or sometimes multiple) predefined target attributes based on a predefined set of predictor attributes. For…

Machine Learning · Computer Science 2020-11-13 Yuan Jin , Wray Buntine , Francois Petitjean , Geoffrey I. Webb

In biomedical Subgroup Discovery, practitioners are interested in discovering interpretable and homogeneous subgroups within a group of patients. In this paper, assuming that healthy subjects (i.e., controls) share common but irrelevant…

Machine Learning · Computer Science 2026-05-21 Robin Louiset , Edouard Duchesnay , Benoit Dufumier , Antoine Grigis , Pietro Gori

Molecular generation and molecular property prediction are both crucial for drug discovery, but they are often developed independently. Inspired by recent studies, which demonstrate that diffusion model, a prominent generative approach, can…

Machine Learning · Computer Science 2025-04-07 Shikun Feng , Yuyan Ni , Yan Lu , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

Gallbladder cancer (GBC) is the most frequent cause of disease among biliary tract neoplasms. Identifying the molecular mechanisms and biomarkers linked to GBC progression has been a significant challenge in scientific research. Few recent…

Globular clusters (GCs) have been at the heart of many longstanding questions in many sub-fields of astronomy and, as such, systematic identification of GCs in external galaxies has immense impacts. In this study, we take advantage of M87's…

How can we identify causal genetic mechanisms that govern bacterial traits? Initial efforts entrusting machine learning models to handle the task of predicting phenotype from genotype return high accuracy scores. However, attempts to…

Genomics · Quantitative Biology 2025-02-12 Tamsin James , Ben Williamson , Peter Tino , Nicole Wheeler

Wide-field, multi-band surveys now detect millions of unresolved sources in nearby galaxy clusters, yet separating globular clusters (GCs) from foreground stars and background galaxies remains challenging. Scalable, automated classification…

In the following paper, we present and discuss challenging applications for fine-grained visual classification (FGVC): biodiversity and species analysis. We not only give details about two challenging new datasets suitable for computer…

Computer Vision and Pattern Recognition · Computer Science 2015-07-06 Erik Rodner , Marcel Simon , Gunnar Brehm , Stephanie Pietsch , J. Wolfgang Wägele , Joachim Denzler

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

Recently, deep learning approaches have become the main research frontier for biological image reconstruction and enhancement problems thanks to their high performance, along with their ultra-fast inference times. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Mehmet Akçakaya , Burhaneddin Yaman , Hyungjin Chung , Jong Chul Ye

Generating molecules, both in a directed and undirected fashion, is a huge part of the drug discovery pipeline. Genetic algorithms (GAs) generate molecules by randomly modifying known molecules. In this paper we show that GAs are very…

Neural and Evolutionary Computing · Computer Science 2023-10-16 Austin Tripp , José Miguel Hernández-Lobato

Our main motivation is to propose an efficient approach to generate novel multi-element stable chemical compounds that can be used in real world applications. This task can be formulated as a combinatorial problem, and it takes many hours…

Machine Learning · Computer Science 2019-05-28 Asma Nouira , Nataliya Sokolovska , Jean-Claude Crivello

Fine-grained visual classification (FGVC) is much more challenging than traditional classification tasks due to the inherently subtle intra-class object variations. Recent works mainly tackle this problem by focusing on how to locate the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Ruoyi Du , Dongliang Chang , Ayan Kumar Bhunia , Jiyang Xie , Zhanyu Ma , Yi-Zhe Song , Jun Guo

Bacterial biofilm segmentation poses significant challenges due to lack of apparent structure, poor imaging resolution, limited contrast between conterminous cells and high density of cells that overlap. Although there exist bacterial…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jie Wang , Tamal Batabyal , Mingxing Zhang , Ji Zhang , Arslan Aziz , Andreas Gahlmann , Scott T. Acton

Constantly discovering novel concepts is crucial in evolving environments. This paper explores the underexplored task of Continual Generalized Category Discovery (C-GCD), which aims to incrementally discover new classes from unlabeled data…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Shijie Ma , Fei Zhu , Zhun Zhong , Wenzhuo Liu , Xu-Yao Zhang , Cheng-Lin Liu
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