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In this work, we present an approach for the efficient treatment of parametrized geometries in the context of POD-Galerkin reduced order methods based on Finite Volume full order approximations. On the contrary to what is normally done in…

Numerical Analysis · Mathematics 2020-02-07 Giovanni Stabile , Matteo Zancanaro , Gianluigi Rozza

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

This article presents a reduced-order modeling methodology via deep convolutional neural networks (CNNs) for shape optimization applications. The CNN provides a nonlinear mapping between the shapes and their associated attributes while…

Optimization and Control · Mathematics 2022-02-16 Wrik Mallik , Neil Farvolden , Jasmin Jelovica , Rajeev K. Jaiman

Nearly all model-reduction techniques project the governing equations onto a linear subspace of the original state space. Such subspaces are typically computed using methods such as balanced truncation, rational interpolation, the…

Numerical Analysis · Computer Science 2019-06-07 Kookjin Lee , Kevin Carlberg

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

Optimization and Control · Mathematics 2021-10-12 Matthias Ebenbeck , Patrik Knopf

A nonlinear-manifold reduced order model (NM-ROM) is a great way of incorporating underlying physics principles into a neural network-based data-driven approach. We combine NM-ROMs with domain decomposition (DD) for efficient computation.…

Numerical Analysis · Mathematics 2023-12-04 Alejandro N. Diaz , Youngsoo Choi , Matthias Heinkenschloss

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Establishing appropriate mathematical models for complex systems in natural phenomena not only helps deepen our understanding of nature but can also be used for state estimation and prediction. However, the extreme complexity of natural…

Machine Learning · Computer Science 2024-03-27 Cheng Fang , Jinqiao Duan

In this paper, we propose a network model, the multiclass classification-based reduced order model (MC-ROM), for solving time-dependent parametric partial differential equations (PPDEs). This work is inspired by the observation of applying…

Numerical Analysis · Mathematics 2022-10-11 Chen Cui , Kai Jiang , Shi Shu

We introduce a novel, computationally inexpensive approach for imaging with an active array of sensors, which probe an unknown medium with a pulse and measure the resulting waves. The imaging function uses a data driven estimate of the…

Numerical Analysis · Mathematics 2022-01-19 Liliana Borcea , Josselin Garnier , Alexander V. Mamonov , Jörn Zimmerling

Reduced-order models are indispensable for multi-query or real-time problems. However, there are still many challenges to constructing efficient ROMs for time-dependent parametrized problems. Using a linear reduced space is inefficient for…

Numerical Analysis · Mathematics 2023-11-17 Junming Duan , Jan S. Hesthaven

In this article, we introduce a modular hybrid analysis and modeling (HAM) approach to account for hidden physics in reduced order modeling (ROM) of parameterized systems relevant to fluid dynamics. The hybrid ROM framework is based on…

Computational Physics · Physics 2020-04-22 Suraj Pawar , Shady E. Ahmed , Omer San , Adil Rasheed

Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

Reliably predicting the future spread of brain tumors using imaging data and on a subject-specific basis requires quantifying uncertainties in data, biophysical models of tumor growth, and spatial heterogeneity of tumor and host tissue.…

Computational Engineering, Finance, and Science · Computer Science 2022-09-27 Baoshan Liang , Jingye Tan , Luke Lozenski , David A. Hormuth , Thomas E. Yankeelov , Umberto Villa , Danial Faghihi

We investigate the use of reduced-order modelling to run discrete element simulations at higher speeds. Taking a data-driven approach, we run many offline simulations in advance and train a model to predict the velocity field from the mass…

Computational Physics · Physics 2021-03-02 Erik Wallin , Martin Servin

High-fidelity simulations, such as computational fluid dynamics and finite element analysis, are essential for modeling complex engineering systems but are often prohibitively expensive for tasks including parametric studies, optimization,…

Machine Learning · Computer Science 2026-05-07 Melika Baghi , Xiao Liu , Kamran Paynabar

In this work, a numerical simulation of 1D Burgers' equation is developed using finite difference method and a reduced order model (ROM) of the simulation is developed using proper orthogonal decomposition (POD). The objective of this work…

Numerical Analysis · Mathematics 2023-03-14 Neelakantan Padmanabhan

We propose a Proper Orthogonal Decomposition (POD)-Galerkin based Reduced Order Model (ROM) for a Leray model. For the implementation of the model, we combine a two-step algorithm called Evolve-Filter (EF) with a computationally efficient…

Numerical Analysis · Mathematics 2021-04-14 Michele Girfoglio , Annalisa Quaini , Gianluigi Rozza

We investigate model order reduction (MOR) strategies for simulating unsteady hemodynamics within cerebrovascular systems, contrasting a physics-based intrusive approach with a data-driven non-intrusive framework. High-fidelity 3D…

Numerical Analysis · Mathematics 2026-03-20 Rahul Halder , Arash Hajisharifi , Kabir Bakhshaei , Gianluigi Rozza

This contribution focuses on the development of Model Order Reduction (MOR) for one-way coupled steady state linear thermomechanical problems in a finite element setting. We apply Proper Orthogonal Decomposition (POD) for the computation of…