Related papers: Learning patient-specific parameters for a diffuse…
In this paper, we propose an equation-based parametric Reduced Order Model (ROM), whose accuracy is improved with data-driven terms added into the reduced equations. These additions have the aim of reintroducing contributions that in…
In this paper, we tackle the problem of reconstructing earlier tumour configurations starting from a single spatial measurement at a later time. We describe the tumour evolution through a diffuse interface model coupling a…
We consider an optimal control problem for a diffuse interface model of tumor growth. The state equations couples a Cahn-Hilliard equation and a reaction-diffusion equation, which models the growth of a tumor in the presence of a nutrient…
This paper proposes a data-driven algorithm for model order reduction (MOR) of large-scale wind farms and studies the effects that the obtained reduced-order model (ROM) has when this is integrated into the power grid. With respect to…
This paper presents a projection-based reduced order modelling (ROM) framework for unsteady parametrized optimal control problems (OCP$_{(\mu)}$s) arising from cardiovascular (CV) applications. In real-life scenarios, accurately defining…
Gliomas are primary brain tumors with a high invasive potential and infiltrative spread. Among them, glioblastoma multiforme (GBM) exhibits microvascular hyperplasia and pronounced necrosis triggered by hypoxia. Histological samples showing…
We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…
This work investigates model order reduction for time-dependent parametrized variational inequalities, with a focus on discrete contact problems. As a prototypical example, we consider an agent-based crowd model [Maury et al., 2011] in…
While data-driven techniques are powerful tools for reduced-order modeling of systems with chaotic dynamics, great potential remains for leveraging known physics (i.e. a full-order model (FOM)) to improve predictive capability. We develop a…
We propose a unified data-driven reduced order model (ROM) that bridges the performance gap between linear and nonlinear manifold approaches. Deep learning ROM (DL-ROM) using deep-convolutional autoencoders (DC-AE) has been shown to capture…
Deep Learning-based Reduced Order Models (DL-ROMs) provide nowadays a well-established class of accurate surrogate models for complex physical systems described by parametrized PDEs, by nonlinearly compressing the solution manifold into a…
The goal of this paper is to assess the utility of Reduced-Order Models (ROMs) developed from 3D physics-based models for predicting transient thermal power output for an enhanced geothermal reservoir while explicitly accounting for…
We discuss solution algorithms for calibrating a tumor growth model using imaging data posed as a deterministic inverse problem. The forward model consists of a nonlinear and time-dependent reaction-diffusion partial differential equation…
Parametric reduced-order modelling often serves as a surrogate method for hemodynamics simulations to improve the computational efficiency in many-query scenarios or to perform real-time simulations. However, the snapshots of the method…
The vast majority of reduced-order models (ROMs) first obtain a low dimensional representation of the problem from high-dimensional model (HDM) training data which is afterwards used to obtain a system of reduced complexity. Unfortunately,…
We introduce here a new diffuse interface thermodynamically consistent non-isothermal model for tumor growth in presence of a nutrient in a domain $\Omega \subset \mathbb{R}^3$. In particular our system describes the growth of a tumor…
Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…
In this paper, a parametric model order reduction (pMOR) technique is proposed to find a simplified system representation of a large-scale and complex thermal system. The main principle behind this technique is that any change of the…
Diffusion models have advanced unsupervised anomaly detection by improving the transformation of pathological images into pseudo-healthy equivalents. Nonetheless, standard approaches may compromise critical information during pathology…
We apply the Proper Orthogonal Decomposition (POD) method for the efficient simulation of several scenarios undergone by Micro-Electro-Mechanical-Systems, involving nonlinearites of geometric and electrostatic nature. The former type of…