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In the context of digital twins, structural health monitoring (SHM) constitutes the backbone of condition-based maintenance, facilitating the interconnection between virtual and physical assets. Guided wave propagation (GWP) is commonly…

Machine Learning · Computer Science 2023-07-20 G. I. Drakoulas , T. V. Gortsas , D. Polyzos

Partial differential equations (PDEs) are widely used for modeling various physical phenomena. These equations often depend on certain parameters, necessitating either the identification of optimal parameters or the solution of the…

Numerical Analysis · Mathematics 2025-10-17 Martina Bukač , Iva Manojlović , Boris Muha , Domagoj Vlah

We propose a component-based (CB) parametric model order reduction (pMOR) formulation for parameterized {nonlinear} elliptic partial differential equations (PDEs). CB-pMOR is designed to deal with large-scale problems for which full-order…

Numerical Analysis · Mathematics 2022-02-22 Kathrin Smetana , Tommaso Taddei

Tumor burden assessment by magnetic resonance imaging (MRI) is central to the evaluation of treatment response for glioblastoma. This assessment is complex to perform and associated with high variability due to the high heterogeneity and…

Modeling tumor growth accurately is essential for understanding cancer progression and informing treatment strategies. To estimate the parameters in the tumor growth model described by a nonlinear PDE, we adopt Physics-Informed Neural…

Analysis of PDEs · Mathematics 2025-11-21 Liu Liu , Yifei Wang , Qinyu Xu , Xiaoqian Xu

Reduced order modeling (ROM) techniques are numerical methods that approximate the solution of parametric partial differential equation (PDE) by properly combining the high-fidelity solutions of the problem obtained for several…

Numerical Analysis · Mathematics 2023-08-08 M. Girfoglio , L. Scandurra , F. Ballarin , G. Infantino , F. Nicolò , A. Montalto , G. Rozza , R. Scrofani , M. Comisso , F. Musumeci

In Laser Powder Bed Fusion (LPBF), the applied laser energy produces high thermal gradients that lead to unacceptable final part distortion. Accurate distortion prediction is essential for optimizing the 3D printing process and…

Machine Learning · Computer Science 2024-12-09 Indu Kant Deo , Youngsoo Choi , Saad A. Khairallah , Alexandre Reikher , Maria Strantza

We present an efficient data-driven regression approach for constructing reduced-order models (ROMs) of reaction-diffusion systems exhibiting pattern formation. The ROMs are learned non-intrusively from available training data of physically…

Pattern Formation and Solitons · Physics 2025-08-12 Alessandro Alla , Rudy Geelen , Hannah Lu

This work proposes a new framework of model reduction for parametric complex systems. The framework employs a popular model reduction technique dynamic mode decomposition (DMD), which is capable of combining data-driven learning and physics…

Numerical Analysis · Mathematics 2022-04-21 Hannah Lu , Daniel M. Tartakovsky

We present a new structure-preserving model order reduction (MOR) framework for large-scale port-Hamiltonian descriptor systems (pH-DAEs). Our method exploits the structural properties of the Rosenbrock system matrix for this system class…

Systems and Control · Electrical Eng. & Systems 2022-10-31 Tim Moser , Boris Lohmann

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Traditional projection-based reduced-order modeling approximates the full-order model by projecting it onto a linear subspace. With a fast-decaying Kolmogorov $n$-width of the solution manifold, the resulting reduced-order model (ROM) can…

Numerical Analysis · Mathematics 2026-03-27 Lijie Ji , Sabrina Rashid , Yanlai Chen , Zhu Wang

POD--Galerkin reduced-order models (ROMs) for fluid-structure interaction problems (incompressible fluid and thin structure) are proposed in this paper. Both the high-fidelity and reduced-order methods are based on a Chorin-Temam…

Numerical Analysis · Mathematics 2017-11-30 Francesco Ballarin , Gianluigi Rozza , Yvon Maday

The paper introduces a reduced order model (ROM) for numerical integration of a dynamical system which depends on multiple parameters. The ROM is a projection of the dynamical system on a low dimensional space that is both problem-dependent…

Numerical Analysis · Mathematics 2022-06-08 Alexander V. Mamonov , Maxim A. Olshanskii

Feedback control synthesis for nonlinear, parameter-dependent fluid flow control problems is considered. The optimal feedback law requires the solution of the Hamilton-Jacobi-Bellman (HJB) PDE suffering the curse of dimensionality. This is…

Optimization and Control · Mathematics 2023-11-29 Sergey Dolgov , Dante Kalise , Luca Saluzzi

We present a fully non-intrusive parametric reduced-order modeling (PROM) framework for geometrically nonlinear structures subject to geometric variations. The method builds upon equation-driven Galerkin ROMs constructed from vibration…

Numerical Analysis · Mathematics 2025-12-09 Alexander Saccani , Paolo Tiso

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

This paper presents a nonlinear reduced-order modeling (ROM) framework that leverages deep learning and manifold learning to predict compressible flow fields with complex nonlinear features, including shock waves. The proposed DeepManifold…

Fluid Dynamics · Physics 2024-12-17 Bilal Mufti , Christian Perron , Dimitri N. Mavris

We consider the inverse problem of parameter estimation in a diffuse interface model for tumour growth. The model consists of a fourth-order Cahn-Hilliard system and contains three phenomenological parameters: the tumour proliferation rate,…

Numerical Analysis · Mathematics 2019-05-10 Christian Kahle , Kei Fong Lam , Jonas Latz , Elisabeth Ullmann

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

Machine Learning · Computer Science 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek
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