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One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

Spectral Computed Tomography (CT) is an emerging technology that enables to estimate the concentration of basis materials within a scanned object by exploiting different photon energy spectra. In this work, we aim at efficiently solving a…

Optimization and Control · Mathematics 2021-03-26 Alessandro Perelli , Martin S. Andersen

Material decomposition refers to using the energy dependence of material physical properties to differentiate materials in a sample, which is a very important application in computed tomography(CT). In propagation-based X-ray phase-contrast…

Medical Physics · Physics 2023-12-01 Suyu Liao , Huitao Zhang , Peng Zhang , Yining Zhu

Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…

Medical Physics · Physics 2022-08-09 Alma Eguizabal , Ozan Öktem , Mats U. Persson

Photon counting detection is a promising approach toward effectively reducing the radiation dose in x-ray computed tomography (CT). Full CT reconstruction from a fraction of the detected photons required by scintillation-based detectors has…

Medical Physics · Physics 2020-08-24 Zheyuan Zhu , Hsin-Hsiung Huang , Shuo Pang

Dual spectral computed tomography (DSCT) can achieve energy- and material-selective images, and has a superior distinguishability of some materials than conventional single spectral computed tomography (SSCT). However, the decomposition…

Optimization and Control · Mathematics 2017-11-22 Qian Wang

Spectral CT is an emerging modality that uses a data acquisition scheme with varied spectral responses to provide enhanced material discrimination in addition to the structural information of conventional CT. Existing clinical and…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Steven Tilley , Jeffrey H. Siewerdsen , J. Webster Stayman

Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…

Medical Physics · Physics 2022-03-01 Nathan Wang , Petteri Haverinen

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Spectral CT has shown promise for high-sensitivity quantitative imaging and material decomposition. This work presents a new device called a spatial-spectral filter (SSF) which consists of a tiled array of filter materials positioned near…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , J. Webster Stayman

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

In this work, we present a method for synthetic CT (sCT) generation from zero-echo-time (ZTE) MRI aimed at structural and quantitative accuracies of the image, with a particular focus on the accurate bone density value prediction. We…

X-ray computed tomography (CT) based on photon counting detectors (PCD) extends standard CT by counting detected photons in multiple energy bins. PCD data can be used to increase the contrast-to-noise ratio (CNR), increase spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Natalie M. Jadue , Madhuri Nagare , Jonathan S. Maltz , Gregery T. Buzzard , Charles A. Bouman

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Weiwen Wu , Haijun Yu , Peijun Chen , Fulin Luo , Fenglin Liu , Qian Wang , Yining Zhu , Yanbo Zhang , Jian Feng , Hengyong Yu

With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…

Medical Physics · Physics 2023-01-25 Yuanwei He , Li Zeng , Qiong Xu , Zhe Wang , Haijun Yu , Zhaoqiang Shen , Zhaojun Yang , Rifeng Zhou

Spectral computed tomography (CT) has a great potential in material identification and decomposition. To achieve high-quality material composition images and further suppress the x-ray beam hardening artifacts, we first propose a one-step…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Weiwen Wu , Qian Wang , Fenglin Liu , Yining Zhu , Hengyong Yu

Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…

Medical Physics · Physics 2023-10-18 Juan C. R. Luna , Mini Das

In spectral CT reconstruction, the basis materials decomposition involves solving a large-scale nonlinear system of integral equations, which is highly ill-posed mathematically. This paper proposes a model that parameterizes the attenuation…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Ligen Shi , Ping Yang , Chang Liu , Wei Zhang , Xing Zhao , Jun Qiu
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