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Loop extrusion is one of the main processes shaping chromosome organisation across the cell cycle, yet its role in regulating DNA entanglement and nucleoplasm viscoelasticity remains overlooked. We simulate entangled solutions of linear…

Soft Condensed Matter · Physics 2025-02-03 Filippo Conforto , Yair Augusto Gutierrez Fosado , Davide Michieletto

We study the nonlinear elastic response of a two-dimensional material to a localized boundary force, with the particular goal of understanding the differences observed between isotropic granular materials and those with hexagonal…

Soft Condensed Matter · Physics 2009-11-13 B. P. Tighe , J. E. S. Socolar

Flexible mechanical metamaterials possess repeating structural motifs that imbue them with novel, exciting properties including programmability, anomalous elastic moduli and nonlinear and robust response. We address such structures via…

Soft Condensed Matter · Physics 2020-03-11 Adrien Saremi , Zeb Rocklin

Confinement can significantly alter fluid properties, offering potential for specific technological applications. However, achieving precise control over the structural complexity of confined fluids and soft matter remains challenging, as…

Soft Condensed Matter · Physics 2024-11-20 Fabio Leoni , Erdal C. Oğuz , Giancarlo Franzese

The close packing density of log-normal and bimodal distributed, surface-adsorbed particles or discs in 2D is studied by numerical simulation. For small spread in particle size, the system orders in a polycrystalline structure of hexagonal…

Soft Condensed Matter · Physics 2012-01-27 Robert D. Groot , Simeon D. Stoyanov

We investigate the crumpling of a sheet as it is repeatedly crushed onto itself by rolling it into a cylinder and twisting it axially while allowing the end-to-end length to evolve freely. As deduced from its plastic deformations, the sheet…

Soft Condensed Matter · Physics 2025-01-22 Amit Dawadi , Arshad Kudrolli

Granular convergence is a property of a granular pack as it is repeatedly sheared in a cyclic, quasistatic fashion, as the packing configuration changes via discrete events. Under suitable conditions the set of microscopic configurations…

Soft Condensed Matter · Physics 2023-08-25 Anna Movsheva , Thomas A. Witten

Deployable structures, essential across various engineering applications ranging from umbrellas to satellites, are evolving to include soft, morphable designs where geometry drives transformation. However, a major challenge for soft…

With decreasing system sizes, the mechanical properties and dominant deformation mechanisms of metals change. For larger scales, bulk behavior is observed that is characterized by a preservation and significant increase of dislocation…

Materials Science · Physics 2021-12-21 Kolja Zoller , Szilvia Kalácska , Péter Dusán Ispánovity , Katrin Schulz

We develop a simple computational model for cell boundary evolution in plastic deformation. We study the cell boundary size distribution and cell boundary misorientation distribution that experimentally have been found to have scaling forms…

Materials Science · Physics 2013-05-29 James P. Sethna , Valerie R. Coffman , Eugene Demler

Many structures inside the cell such as nucleosomes and protein-mediated DNA loops contain sharply bent double-stranded (ds) DNA. Therefore, the energetics of strong dsDNA bending constitutes an essential part of cellular thermodynamics.…

Biological Physics · Physics 2014-11-05 Tung T. Le , Harold D. Kim

We have studied structure formation in a confined block copolymer melt by means of dynamic density functional theory (DDFT). The confinement is two-dimensional, and the confined geometry is that of a cylindrical nanopore. Although the…

Soft Condensed Matter · Physics 2009-11-13 G. J. A. Sevink , A. V. Zvelindovsky

Nanoscale and microscale confinement of biopolymers naturally occurs in cells and has been recently achieved in artificial structures designed for nanotechnological applications. Here, we present an extensive theoretical investigation of…

Soft Condensed Matter · Physics 2007-06-13 Frederik Wagner , Gianluca Lattanzi , Erwin Frey

The continuous packing of a flexible rod in two-dimensional cavities yields a countable set of interacting domains that resembles non-equilibrium cellular systems and belongs to a new class of light-weight material. However, the link…

Soft Condensed Matter · Physics 2017-03-13 T A Sobral , M A F Gomes

We present the experimental studies of highly strained soft bidisperse granular systems made of hyperelastic and plastic particles. We explore the behavior of granular matter deep in the jammed state from local field measurement from the…

Soft Condensed Matter · Physics 2019-10-30 Thi-Lo Vu , Jonathan Barés

This study focuses on comparing the individual polymer chain dynamics in an entangled polymeric liquid under different shear and extension rates. Polymer chains under various shear rates and extension rates were simulated using a…

Chemical Physics · Physics 2021-01-15 Behrouz Behdani , Tong Mou , Cody Spratt , Slava Butcovich , Ryan Gettler , Joontaek Park

The aim of the present paper is the study of the entropic elasticity of the dsDNA molecule, having a cristallographic length L of the order of 10 to 30 persistence lengths A, when it is subject to spatial obstructions. We have not tried to…

Soft Condensed Matter · Physics 2009-11-11 C. Bouchiat

Lattice-model simulations and experiments of some small proteins suggest that folding is essentially controlled by a few conserved contacts. Residues of these conserved contacts form the minimum set of native contacts needed to ensure…

Biomolecules · Quantitative Biology 2011-09-14 Wei-Mou Zheng , Hui Zeng , Dong-Bo Bu , Ming-Fu Shao , Ke-Song Liu , Chao Wang

Localized deformation patterns are a common motif in morphogenesis and are increasingly finding widespread applications in materials science, for instance as memory devices. Here we describe the emergence of spatially localized deformations…

Soft Condensed Matter · Physics 2019-06-12 Thomas C. T. Michaels , Remy Kusters , Alexander J. Dear , Cornelis Storm , James C. Weaver , L. Mahadevan

We model two-dimensional systems of granular aggregates confined between two planes and demonstrate that at a critical grain volume fraction an abrupt rigidity transition occurs. This transition is observed both in static and shear tests.…

Disordered Systems and Neural Networks · Physics 2007-05-23 Einat Aharonov , David Sparks