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Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

Biological tissues are complex structures composed of many elements which make light-based tissue diagnostics challenging. Over the past decades, Monte Carlo technique has been used as a fundamental and versatile approach toward modeling…

Optics · Physics 2024-05-17 Maryam Ghahremani

Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from…

Neural and Evolutionary Computing · Computer Science 2014-09-10 Andrea Soltoggio

The compact size, scalability, and strongly confined fields in integrated photonic devices enable new functionalities in photonic networking and information processing, both classical and quantum. Gallium phosphide (GaP) is a promising…

Feedback control schemes are a promising way to manipulate transport properties of driven colloidal suspensions. In the present article we suggest a feedback scheme to enhance the collective transport of colloidal particles with repulsive…

Soft Condensed Matter · Physics 2015-08-26 Robert Gernert , Sabine H. L. Klapp

Cell motion inside dense tissues governs many biological processes, including embryonic development and cancer metastasis, and recent experiments suggest that these tissues exhibit collective glassy behavior. To make quantitative…

Biological Physics · Physics 2016-04-27 Dapeng Bi , Xingbo Yang , M. Cristina Marchetti , M. Lisa Manning

An optical flow gradient algorithm was applied to spontaneously forming net- works of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling with single pixel resolution. Optical…

Computational Engineering, Finance, and Science · Computer Science 2010-01-22 Marius Buibas , Diana Yu , Krystal Nizar , Gabriel A. Silva

We present a model for the effect of stress on thin amorphous films that develop atop ion-irradiated silicon, based on the mechanism of ion-induced anisotropic plastic flow. Using only parameters directly measured or known to high accuracy,…

Mathematical Physics · Physics 2015-06-05 Scott A. Norris

The dynamics of higher-order topological signals are increasingly recognized as a key aspect of the activity of complex systems. A paradigmatic example are synaptic dynamics: synaptic efficacy changes over time driven by different…

Neurons and Cognition · Quantitative Biology 2025-07-11 Gustavo Menesse , Ana P. Millán , Joaquín J. Torres

Real-time tracking of high-speed objects in cognitive tasks is challenging in the present artificial intelligence techniques because the data processing and computation are time-consuming resulting in impeditive time delays. A…

Applied Physics · Physics 2020-11-05 Qi Zheng , Yuanyuan Mi , Xiaorui Zhu , Zhe Yuan , Ke Xia

We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

Microstructural changes in solids, driven by energy flows, do not develop in a static continuous space, such as the space considered in conventional plasticity models. The applied forces create an evolving internal energy landscape, which…

Materials Science · Physics 2024-12-19 Elijah Borodin , Afonso D. M. Barroso , Andrey P. Jivkov

The aim of this work is to prove that it is possible to realise an optical system which produces as output a light intensity that can be expressed in the same mathematical form of the spin glass Hamiltonian. The optical system under study…

Disordered Systems and Neural Networks · Physics 2020-10-27 Erik Hörmann

Cell-free translational strategies are needed to accelerate the repair of mineralised tissues, particularly large bone defects, using minimally invasive approaches. Regenerative bone scaffolds should ideally mimic aspects of the tissue's…

Tissues and Organs · Quantitative Biology 2021-01-06 Robabeh Gharaei , Giuseppe Tronci , Parikshit Goswami , Robert P. Wynn Davies , Jennifer Kirkham , Stephen J. Russell

Ultranarrow-linewidth atoms coupled to a lossy optical cavity mode synchronize, i.e. develop correlations, and exhibit steady-state superradiance when continuously repumped. This type of system displays rich collective physics and promises…

Quantum Physics · Physics 2017-03-29 Athreya Shankar , John Cooper , Justin G. Bohnet , John J. Bollinger , Murray Holland

Many processes in chemistry, physics, and biology involve rare events in which the system escapes from a metastable state by surmounting an activation barrier. Examples range from chemical reactions, protein folding, and nucleation events…

Chemical Physics · Physics 2020-10-07 Niels Zijlstra , Daniel Nettels , Rohit Satija , Dmitrii E. Makarov , Benjamin Schuler

We develop a coarse grained (CG) approach for efficiently simulating calcium dynamics in the endoplasmic reticulum membrane based on a fine stochastic lattice gas model. By grouping neighboring microscopic sites together into CG cells and…

Chemical Physics · Physics 2015-06-15 Chuansheng Shen , Hanshuang Chen

Quantification of neuronal correlations in neuron populations helps us to understand neural coding rules. Such quantification could also reveal how neurons encode information in normal and disease conditions like Alzheimer's and…

Neurons and Cognition · Quantitative Biology 2021-05-10 Sathish Ande , Srinivas Avasarala , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

The endeavor to understand the brain involves multiple collaborating research fields. Classically, synaptic plasticity rules derived by theoretical neuroscientists are evaluated in isolation on pattern classification tasks. This contrasts…

Triplet-based Spike Timing Dependent Plasticity (TSTDP) is a powerful synaptic plasticity rule that acts beyond conventional pair-based STDP (PSTDP). Here, the TSTDP is capable of reproducing the outcomes from a variety of biological…

Neural and Evolutionary Computing · Computer Science 2013-04-02 Mostafa Rahimi Azghadi , Said Al-Sarawi , Derek Abbott , Nicolangelo Iannella