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The ability of deep neural networks to learn complex data relations and representations is established nowadays, but it generally relies on large sets of training data. This work explores a "piece-specific" autoencoding scheme, in which a…

Sound · Computer Science 2022-03-09 Axel Marmoret , Jérémy E. Cohen , Frédéric Bimbot

Datasets from single-molecule experiments often reflect a large variety of molecular behaviour. The exploration of such datasets can be challenging, especially if knowledge about the data is limited and a priori assumptions about expected…

Data Analysis, Statistics and Probability · Physics 2020-04-06 Anton Vladyka , Tim Albrecht

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Despite their great success in practical applications, there is still a lack of theoretical and systematic methods to analyze deep neural networks. In this paper, we illustrate an advanced information theoretic methodology to understand the…

Machine Learning · Computer Science 2019-05-09 Shujian Yu , Jose C. Principe

How can agents learn internal models that veridically represent interactions with the real world is a largely open question. As machine learning is moving towards representations containing not just observational but also interventional…

Machine Learning · Computer Science 2024-07-03 Hamza Keurti , Hsiao-Ru Pan , Michel Besserve , Benjamin F. Grewe , Bernhard Schölkopf

Predicting future trajectories of traffic agents in highly interactive environments is an essential and challenging problem for the safe operation of autonomous driving systems. On the basis of the fact that self-driving vehicles are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Chiho Choi , Joon Hee Choi , Jiachen Li , Srikanth Malla

Predicting future trajectories of traffic agents in highly interactive environments is an essential and challenging problem for the safe operation of autonomous driving systems. On the basis of the fact that self-driving vehicles are…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Chiho Choi , Joon Hee Choi , Srikanth Malla , Jiachen Li

A rigorous understanding of how multicellular behaviors arise from the actions of single cells requires quantitative frameworks that bridge the gap between genetic circuits, the arrangement of cells in space, and population-level behaviors.…

Molecular Networks · Quantitative Biology 2016-02-18 Théo Maire , Hyun Youk

The task of inferring high-level causal variables from low-level observations, commonly referred to as causal representation learning, is fundamentally underconstrained. As such, recent works to address this problem focus on various…

Machine Learning · Statistics 2024-03-26 Simon Bing , Urmi Ninad , Jonas Wahl , Jakob Runge

We propose Masked Capsule Autoencoders (MCAE), the first Capsule Network that utilises pretraining in a modern self-supervised paradigm, specifically the masked image modelling framework. Capsule Networks have emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Miles Everett , Mingjun Zhong , Georgios Leontidis

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Xiang Li , Aoxiao Zhong , Ming Lin , Ning Guo , Mu Sun , Arkadiusz Sitek , Jieping Ye , James Thrall , Quanzheng Li

Recent advances in representation learning have demonstrated an ability to represent information from different modalities such as video, text, and audio in a single high-level embedding vector. In this work we present a self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2021-06-11 Alexander H. Liu , SouYoung Jin , Cheng-I Jeff Lai , Andrew Rouditchenko , Aude Oliva , James Glass

Neurons process information in ways that depend on their cell type, connectivity, and the brain region in which they are embedded. However, inferring these factors from neural activity remains a significant challenge. To build…

Machine Learning · Computer Science 2025-12-02 Vinam Arora , Divyansha Lachi , Ian J. Knight , Mehdi Azabou , Blake Richards , Cole L. Hurwitz , Josh Siegle , Eva L. Dyer

Single-cell technologies enable comprehensive profiling of diverse immune cell-types through the measurement of multiple genes or proteins per individual cell. In order to translate immune signatures assayed from blood or tissue into…

Machine Learning · Computer Science 2024-11-26 Chi-Jane Chen , Haidong Yi , Natalie Stanley

Autoencoders are powerful machine learning models used to compress information from multiple data sources. However, autoencoders, like all artificial neural networks, are often unidentifiable and uninterpretable. This research focuses on…

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Recent NLP studies reveal that substantial linguistic information can be attributed to single neurons, i.e., individual dimensions of the representation vectors. We hypothesize that modeling strong interactions among neurons helps to better…

Computation and Language · Computer Science 2019-11-25 Jian Li , Xing Wang , Baosong Yang , Shuming Shi , Michael R. Lyu , Zhaopeng Tu

Single-cell analysis is currently one of the most high-resolution techniques to study biology. The large complex datasets that have been generated have spurred numerous developments in computational biology, in particular the use of…

Genomics · Quantitative Biology 2023-04-27 Ionut Sebastian Mihai , Sarang Chafle , Johan Henriksson

Layered neural networks have greatly improved the performance of various applications including image processing, speech recognition, natural language processing, and bioinformatics. However, it is still difficult to discover or interpret…

Machine Learning · Statistics 2017-10-05 Chihiro Watanabe , Kaoru Hiramatsu , Kunio Kashino

The analysis of deforming 3D surface meshes is accelerated by autoencoders since the low-dimensional embeddings can be used to visualize underlying dynamics. But, state-of-the-art mesh convolutional autoencoders require a fixed connectivity…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Sara Hahner , Jochen Garcke