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In recent years, the focus of bioinformatics research has moved from individual sequences to collections of sequences. Given the fundamental role of the Burrows-Wheeler Transform (BWT) in string processing, a number of dedicated tools have…

Data Structures and Algorithms · Computer Science 2025-05-28 Davide Cenzato , Zsuzsanna Lipták

Motivation: Burrows-Wheeler Transform (BWT) is a common component in full-text indices. Initially developed for data compression, it is particularly powerful for encoding redundant sequences such as pangenome data. However, BWT construction…

Genomics · Quantitative Biology 2025-09-10 Heng Li

Compressed suffix arrays (CSAs) index large repetitive collections and are key in many text applications. The r-index and its derivatives combine the run-length Burrows-Wheeler Transform (BWT) with suffix array sampling to achieve space…

Data Structures and Algorithms · Computer Science 2026-02-20 Diego Díaz-Domínguez , Veli Mäkinen

The Positional Burrows--Wheeler Transform (PBWT) is a data structure designed for efficiently representing and querying large collections of sequences, such as haplotype panels in genomics. Forward and backward stepping operations --…

Data Structures and Algorithms · Computer Science 2026-02-17 Paola Bonizzoni , Davide Cozzi , Younan Gao

In this paper we study the number $r_{bwt}$ of equal-letter runs produced by the Burrows-Wheeler transform ($BWT$) when it is applied to purely morphic finite words, which are words generated by iterating prolongable morphisms. Such a…

Formal Languages and Automata Theory · Computer Science 2022-02-08 Andrea Frosini , Ilaria Mancini , Simone Rinaldi , Giuseppe Romana , Marinella Sciortino

The Burrows-Wheeler Transform (BWT) is an important technique both in data compression and in the design of compact indexing data structures. It has been generalized from single strings to collections of strings and some classes of labeled…

Data Structures and Algorithms · Computer Science 2019-05-30 Jarno Alanko , Travis Gagie , Gonzalo Navarro , Louisa Seelbach Benkner

We study how the application of injective morphisms affects the number $r$ of equal-letter runs in the Burrows-Wheeler Transform (BWT). This parameter has emerged as a key repetitiveness measure in compressed indexing. We focus on the…

Formal Languages and Automata Theory · Computer Science 2025-04-25 Gabriele Fici , Giuseppe Romana , Marinella Sciortino , Cristian Urbina

We show how to build several data structures of central importance to string processing, taking as input the Burrows-Wheeler transform (BWT) and using small extra working space. Let $n$ be the text length and $\sigma$ be the alphabet size.…

Data Structures and Algorithms · Computer Science 2019-08-14 Nicola Prezza , Giovanna Rosone

Indexing of very large collections of strings such as those produced by the widespread sequencing technologies, heavily relies on multi-string generalizations of the Burrows-Wheeler Transform (BWT), and for this problem various in-memory…

Data Structures and Algorithms · Computer Science 2016-07-29 Paola Bonizzoni , Gianluca Della Vedova , Serena Nicosia , Marco Previtali , Raffaella Rizzi

In this paper we propose a flexible and lightweight technique for merging compressed indices based on variants of Burrows-Wheeler transform (BWT), thus addressing the need for algorithms that compute compressed indices over large…

Data Structures and Algorithms · Computer Science 2019-03-06 Lavinia Egidi , Giovanni Manzini

We show that the Longest Common Prefix Array of a text collection of total size n on alphabet [1, {\sigma}] can be computed from the Burrows-Wheeler transformed collection in O(n log {\sigma}) time using o(n log {\sigma}) bits of working…

Data Structures and Algorithms · Computer Science 2019-01-23 Nicola Prezza , Giovanna Rosone

We show how to merge two run-length compressed Burrows-Wheeler Transforms (RLBWTs) into a run-length compressed extended Burrows-Wheeler Transform (eBWT) in $O (r)$ space and $O ((r + L) \log (m + n))$ time, where $m$ and $n$ are the…

Data Structures and Algorithms · Computer Science 2026-04-16 Travis Gagie

Popular sequence alignment tools such as BWA convert a reference genome to an indexing data structure based on the Burrows-Wheeler Transform (BWT), from which matches to individual query sequences can be rapidly determined. However the…

Genomics · Quantitative Biology 2013-04-23 Anthony J. Cox , Tobias Jakobi , Giovanna Rosone , Ole B. Schulz-Trieglaff

In this paper, we show that the LZ77 factorization of a text T {\in\Sigma^n} can be computed in O(R log n) bits of working space and O(n log R) time, R being the number of runs in the Burrows-Wheeler transform of T reversed. For extremely…

Data Structures and Algorithms · Computer Science 2015-10-22 Nicola Prezza , Alberto Policriti

In this article we extend the elegant in-place Burrows-Wheeler transform (BWT) algorithm proposed by Crochemore et al. (Crochemore et al., 2015). Our extension is twofold: we first show how to compute simultaneously the longest common…

Data Structures and Algorithms · Computer Science 2018-06-08 Felipe A. Louza , Travis Gagie , Guilherme P. Telles

We study the impact that string reversal can have on several repetitiveness measures. First, we exhibit an infinite family of strings where the number, $r$, of runs in the run-length encoding of the Burrows--Wheeler transform (BWT) can…

Data Structures and Algorithms · Computer Science 2026-02-17 Hideo Bannai , Yuto Fujie , Peaker Guo , Shunsuke Inenaga , Yuto Nakashima , Simon J. Puglisi , Cristian Urbina

The run-length compressed Burrows-Wheeler transform (RLBWT) used in conjunction with the backward search introduced in the FM index is the centerpiece of most compressed indexes working on highly-repetitive data sets like biological…

Data Structures and Algorithms · Computer Science 2021-10-05 Jin Jie Deng , Wing-Kai Hon , Dominik Köppl , Kunihiko Sadakane

Indexing highly repetitive texts --- such as genomic databases, software repositories and versioned text collections --- has become an important problem since the turn of the millennium. A relevant compressibility measure for repetitive…

Data Structures and Algorithms · Computer Science 2017-07-13 Travis Gagie , Gonzalo Navarro , Nicola Prezza

We prove that for every integer $n > 0$ and for every alphabet $\Sigma_k$ of size $k \geq 3$, there exists a necklace of length $n$ whose Burrows-Wheeler Transform (BWT) is completely unclustered, i.e., it consists of exactly $n$ runs with…

Discrete Mathematics · Computer Science 2025-08-29 Gabriele Fici , Estéban Gabory , Giuseppe Romana , Marinella Sciortino

A weight based dynamic compression method has recently been proposed, which is especially suitable for the encoding of files with locally skewed distributions. Its main idea is to assign larger weights to closer to be encoded symbols by…

Data Structures and Algorithms · Computer Science 2021-05-24 Aharon Fruchtman , Yoav Gross , Shmuel T. Klein , Dana Shapira