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Semantic segmentation networks (SSNs) are central to safety-critical applications such as medical imaging and autonomous driving, where robustness under uncertainty is essential. However, existing probabilistic verification methods often…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Navid Hashemi , Samuel Sasaki , Diego Manzanas Lopez , Lars Lindemann , Ipek Oguz , Meiyi Ma , Taylor T. Johnson

Background and objective: Prior probability shift between training and deployment datasets challenges deep learning-based medical image classification. Standard correction methods reweight posterior probabilities to adjust prior bias, yet…

Quantitative Methods · Quantitative Biology 2025-11-06 Takaaki Tachibana , Toru Nagasaka , Yukari Adachi , Hiroki Kagiyama , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…

Medical Physics · Physics 2024-03-28 Yu-Hua Huang , Xinzhi Teng , Jiang Zhang , Zhi Chen , Zongrui Ma , Ge Ren , Feng-Ming , Kong , Jing Cai

Automated segmentation of Lungs plays a crucial role in the computer-aided diagnosis of chest X-Ray (CXR) images. Developing an efficient Lung segmentation model is challenging because of difficulties such as the presence of several edges…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Jyoti Islam , Yanqing Zhang

We propose a statistical framework to integrate radiological magnetic resonance imaging (MRI) and genomic data to identify the underlying radiogenomic associations in lower grade gliomas (LGG). We devise a novel imaging phenotype by…

We address the selection and evaluation of uncertain segmentation methods in medical imaging and present two case studies: prostate segmentation, illustrating that for minimal annotator variation simple deterministic models can suffice, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Jes Frellsen , Aasa Feragen

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

Deep learning based image segmentation methods have achieved great success, even having human-level accuracy in some applications. However, due to the black box nature of deep learning, the best method may fail in some situations. Thus…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Leixin Zhou , Wenxiang Deng , Xiaodong Wu

The Random Walks (RW) algorithm is one of the most e - cient and easy-to-use probabilistic segmentation methods. By combining contrast terms with prior terms, it provides accurate segmentations of medical images in a fully automated manner.…

Computer Vision and Pattern Recognition · Computer Science 2013-09-02 Pierre-Yves Baudin , Danny Goodman , Puneet Kumar , Noura Azzabou , Pierre G. Carlier , Nikos Paragios , M. Pawan Kumar

Despite the popularity and empirical success of patch-based nearest-neighbor and weighted majority voting approaches to medical image segmentation, there has been no theoretical development on when, why, and how well these nonparametric…

Computer Vision and Pattern Recognition · Computer Science 2015-10-07 George Chen , Devavrat Shah , Polina Golland

For most if not all cancers, prognosis is of significant importance, and extensive modeling research has been conducted. With the genetic nature of cancer, in the past two decades, multiple types of molecular data (such as gene expressions…

Applications · Statistics 2020-06-09 Sanguo Zhang , Yu Fan , Tingyan Zhong , Shuangge Ma

While lung cancer is the second most diagnosed form of cancer in men and women, a sufficiently early diagnosis can be pivotal in patient survival rates. Imaging-based, or radiomics-driven, detection methods have been developed to aid…

Neural and Evolutionary Computing · Computer Science 2017-10-23 Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

In this work, we develop an attention convolutional neural network (CNN) to segment brain tumors from Magnetic Resonance Images (MRI). Further, we predict the survival rate using various machine learning methods. We adopt a 3D UNet…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , Vibashan VS , V Jeya Maria Jose , Navodini Wijethilake , Uppal Utkarsh , Hongliang Ren

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

We propose the Generalized Probabilistic U-Net, which extends the Probabilistic U-Net by allowing more general forms of the Gaussian distribution as the latent space distribution that can better approximate the uncertainty in the reference…

Computer Vision and Pattern Recognition · Computer Science 2023-07-03 Ishaan Bhat , Josien P. W. Pluim , Max A. Viergever , Hugo J. Kuijf

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Automatic segmentation of head and neck cancer (HNC) tumors and lymph nodes plays a crucial role in the optimization treatment strategy and prognosis analysis. This study aims to employ nnU-Net for automatic segmentation and radiomics for…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Hui Xu , Yihao Li , Wei Zhao , Gwenolé Quellec , Lijun Lu , Mathieu Hatt