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Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…
Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…
Automatic pathological pulmonary lobe segmentation(PPLS) enables regional analyses of lung disease, a clinically important capability. Due to often incomplete lobe boundaries, PPLS is difficult even for experts, and most prior art requires…
Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…
Objective: Radiomics, an emerging tool for medical image analysis, is potential towards precisely characterizing gastric cancer (GC). Whether using one-slice 2D annotation or whole-volume 3D annotation remains a long-time debate, especially…
Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…
Deep learning models are increasingly used for radiographic analysis, but their reliability is challenged by the stochastic noise inherent in clinical imaging. A systematic, cross-task understanding of how different noise types impact these…
Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…
When deploying segmentation models in practice, it is critical to evaluate their behaviors in varied and complex scenes. Different from the previous evaluation paradigms only in consideration of global attribute variations (e.g. adverse…
One of the fundamental problems in computer vision is image segmentation, the task of detecting distinct regions or objects in given images. Deep Neural Networks (DNN) have been shown to be very effective in segmenting challenging images,…
Medical image segmentation models are typically optimised with voxel-wise losses that constrain predictions only in the output space. This leaves latent feature representations largely unconstrained, potentially limiting generalisation. We…
Background and Objectives: Predicting patient response to treatment and survival in oncology is a prominent way towards precision medicine. To that end, radiomics was proposed as a field of study where images are used instead of invasive…
This work proposed kernel selection approaches for probabilistic classifiers based on features produced by the convolutional encoder of a variational autoencoder. Particularly, the developed methodologies allow the selection of the most…
Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…
The computer-aided diagnosis system we developed for the mass characterization is mainly based on a segmentation algorithm and on the neural classification of several features computed on the segmented mass. Mass segmentation plays a key…
Cancer patient diagnosis and prognosis is informed by assessment of morphological properties observed in patient tissue. Pathologists normally carry out this assessment, yet advances in computational image analysis provide opportunities for…
Motivated by the increasing popularity of transformers in computer vision, in recent times there has been a rapid development of novel architectures. While in-domain performance follows a constant, upward trend, properties like robustness…
Radiomics involves the study of tumor images to identify quantitative markers explaining cancer heterogeneity. The predominant approach is to extract hundreds to thousands of image features, including histogram features comprised of…
In the field of non-invasive medical imaging, radiomic features are utilized to measure tumor characteristics. However, these features can be affected by the techniques used to discretize the images, ultimately impacting the accuracy of…
An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…