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Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

In biomedical and neurodegenerative disorders, accurate and early disease identification remains challenging due to the scarcity of labeled data and the complexity of imaging patterns. To address these challenges, we introduce ARMA-C3, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 VSS Tejaswi Abburi , Saurabh J. Shigwan , Nitin Kumar

Binary determination of the presence of objects is one of the problems where humans perform extraordinarily better than computer vision systems, in terms of both speed and preciseness. One of the possible reasons is that humans can skip…

Machine Learning · Computer Science 2019-06-05 Baoxiang Wang

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

Applications · Statistics 2026-05-25 J. M. Gorriz , F. Segovia , C. Jimenez , J. E. Arco , F. J. Martinez , J Ramirez , S. Abulikemu , J. Suckling

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

Image and Video Processing · Electrical Eng. & Systems 2019-01-30 GuruRaj Awate

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

In visual object classification, humans often justify their choices by comparing objects to prototypical examples within that class. We may therefore increase the interpretability of deep learning models by imbuing them with a similar style…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Ayodeji Ijishakin , Ahmed Abdulaal , Adamos Hadjivasiliou , Sophie Martin , James Cole

Early diagnosis of Alzheimer's disease (AD) remains a major challenge due to the subtle and temporally irregular progression of structural brain changes in the prodromal stages. Existing deep learning approaches require large longitudinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Maxx Richard Rahman , Mostafa Hammouda , Wolfgang Maass

Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…

Computer Vision and Pattern Recognition · Computer Science 2019-10-15 Gururaj Awate , Sunil Bangare , G Pradeepini , S Patil

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

Deep learning models have shown strong performance in classifying Alzheimer's disease (AD) from R2* maps, but their decision-making remains opaque, raising concerns about interpretability. Previous studies suggest biases in model decisions,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Christian Tinauer , Maximilian Sackl , Stefan Ropele , Christian Langkammer

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

Machine Learning · Computer Science 2021-01-13 Alexander Lavin

We design an Enriched Deep Recurrent Visual Attention Model (EDRAM) - an improved attention-based architecture for multiple object recognition. The proposed model is a fully differentiable unit that can be optimized end-to-end by using…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Artsiom Ablavatski , Shijian Lu , Jianfei Cai

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…